Human leishmaniasis vaccines: Use cases, target population and potential global demand.

• Published in: PLOS Neglected Tropical Diseases
• Main Authors: Stefano Malvolti, Melissa Malhame, Carsten F Mantel, Epke A Le Rutte, Paul M Kaye
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2021
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; Azar
• Online Access: https://doi.org/10.1371/journal.pntd.0009742; https://doaj.org/article/0464839d58004701bab69217b060d1b0

The development of vaccines against one or all forms of human leishmaniasis remains hampered by a paucity of investment, at least in part resulting from the lack of well-evidenced and agreed estimates of vaccine demand. Starting from the definition of 4 main use cases (prevention of visceral leishma...