Systemic protothecosis in an immunocompetent patient
Abstract Background Although uncommon, there is increasing interest and public health concerns of the pathogen Prototheca spp, a ubiquitous achlorophilic microalgae that can affect both humans and animals. High mortality rates have been reported in immunocompromised patients with disseminated infect...
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Online Access: | https://doi.org/10.1186/s40794-022-00180-8 https://doaj.org/article/03e7ce5d3ef94943bc1f2126fea02556 |
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ftdoajarticles:oai:doaj.org/article:03e7ce5d3ef94943bc1f2126fea02556 2023-05-15T15:05:13+02:00 Systemic protothecosis in an immunocompetent patient Alvano Trespalacios Sierra Bárbara Arroyo-Salgado Jesús Rodriguez-Blanco Ingrid Tibocha Gordon María Cristina Martínez-Ávila 2022-10-01T00:00:00Z https://doi.org/10.1186/s40794-022-00180-8 https://doaj.org/article/03e7ce5d3ef94943bc1f2126fea02556 EN eng BMC https://doi.org/10.1186/s40794-022-00180-8 https://doaj.org/toc/2055-0936 doi:10.1186/s40794-022-00180-8 2055-0936 https://doaj.org/article/03e7ce5d3ef94943bc1f2126fea02556 Tropical Diseases, Travel Medicine and Vaccines, Vol 8, Iss 1, Pp 1-5 (2022) Emerging diseases protothecosis Prototheca wickerhamii algaemia treatment Arctic medicine. Tropical medicine RC955-962 article 2022 ftdoajarticles https://doi.org/10.1186/s40794-022-00180-8 2022-12-30T23:28:16Z Abstract Background Although uncommon, there is increasing interest and public health concerns of the pathogen Prototheca spp, a ubiquitous achlorophilic microalgae that can affect both humans and animals. High mortality rates have been reported in immunocompromised patients with disseminated infection, but no data is available in the immunocompetent population. Case Presentation We present the case of a 59-year-old man from rural area of Colombia who was admitted to the intensive care unit due to decompensated heart failure that was difficult to medically manage, with development of septic shock and isolation of Prototheca wickerhamii from blood culture. Fluconazole and Amphotericin B were given with successful outcome. Conclusions To date, protothecosis and its virulence factors and pathogenesis remain to be fully understood, in our case the isolation of this microalga and its implication of exacerbating chronic conditions such as heart failure is unclear. The medical-scientific community is invited to study this microorganism to determine effective management strategies, as well as its timely identification, treatment, and control, to avoid fatal outcomes. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Tropical Diseases, Travel Medicine and Vaccines 8 1 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Emerging diseases protothecosis Prototheca wickerhamii algaemia treatment Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Emerging diseases protothecosis Prototheca wickerhamii algaemia treatment Arctic medicine. Tropical medicine RC955-962 Alvano Trespalacios Sierra Bárbara Arroyo-Salgado Jesús Rodriguez-Blanco Ingrid Tibocha Gordon María Cristina Martínez-Ávila Systemic protothecosis in an immunocompetent patient |
topic_facet |
Emerging diseases protothecosis Prototheca wickerhamii algaemia treatment Arctic medicine. Tropical medicine RC955-962 |
description |
Abstract Background Although uncommon, there is increasing interest and public health concerns of the pathogen Prototheca spp, a ubiquitous achlorophilic microalgae that can affect both humans and animals. High mortality rates have been reported in immunocompromised patients with disseminated infection, but no data is available in the immunocompetent population. Case Presentation We present the case of a 59-year-old man from rural area of Colombia who was admitted to the intensive care unit due to decompensated heart failure that was difficult to medically manage, with development of septic shock and isolation of Prototheca wickerhamii from blood culture. Fluconazole and Amphotericin B were given with successful outcome. Conclusions To date, protothecosis and its virulence factors and pathogenesis remain to be fully understood, in our case the isolation of this microalga and its implication of exacerbating chronic conditions such as heart failure is unclear. The medical-scientific community is invited to study this microorganism to determine effective management strategies, as well as its timely identification, treatment, and control, to avoid fatal outcomes. |
format |
Article in Journal/Newspaper |
author |
Alvano Trespalacios Sierra Bárbara Arroyo-Salgado Jesús Rodriguez-Blanco Ingrid Tibocha Gordon María Cristina Martínez-Ávila |
author_facet |
Alvano Trespalacios Sierra Bárbara Arroyo-Salgado Jesús Rodriguez-Blanco Ingrid Tibocha Gordon María Cristina Martínez-Ávila |
author_sort |
Alvano Trespalacios Sierra |
title |
Systemic protothecosis in an immunocompetent patient |
title_short |
Systemic protothecosis in an immunocompetent patient |
title_full |
Systemic protothecosis in an immunocompetent patient |
title_fullStr |
Systemic protothecosis in an immunocompetent patient |
title_full_unstemmed |
Systemic protothecosis in an immunocompetent patient |
title_sort |
systemic protothecosis in an immunocompetent patient |
publisher |
BMC |
publishDate |
2022 |
url |
https://doi.org/10.1186/s40794-022-00180-8 https://doaj.org/article/03e7ce5d3ef94943bc1f2126fea02556 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Tropical Diseases, Travel Medicine and Vaccines, Vol 8, Iss 1, Pp 1-5 (2022) |
op_relation |
https://doi.org/10.1186/s40794-022-00180-8 https://doaj.org/toc/2055-0936 doi:10.1186/s40794-022-00180-8 2055-0936 https://doaj.org/article/03e7ce5d3ef94943bc1f2126fea02556 |
op_doi |
https://doi.org/10.1186/s40794-022-00180-8 |
container_title |
Tropical Diseases, Travel Medicine and Vaccines |
container_volume |
8 |
container_issue |
1 |
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1766336952832884736 |