Vertical transmission of HIV-1 in the western region of the State of São Paulo
INTRODUCTION: This study aimed to determine the prevalence of vertical HIV-1 transmission in the western region of the State of São Paulo, Brazil. METHODS: The study analyzed the medical records of HIV-1-infected mothers and infant pairs living in the municipalities of São Paulo Regional Health Depa...
Published in: | Revista da Sociedade Brasileira de Medicina Tropical |
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ftdoajarticles:oai:doaj.org/article:03689adc7ab041fb9113fbe6d497ea8c 2023-05-15T15:13:12+02:00 Vertical transmission of HIV-1 in the western region of the State of São Paulo Vera Lúcia Maria Alves Gonçalves Charlene Troiani Armênio Alcântara Ribeiro Patrícia Rodrigues Naufal Spir Elza Keiko Kimura Gushiken Renata Bonfim Vieira Luiz Euribel Prestes-Carneiro 2011-02-01T00:00:00Z https://doi.org/10.1590/S0037-86822011000100002 https://doaj.org/article/03689adc7ab041fb9113fbe6d497ea8c EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822011000100002&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/S0037-86822011000100002 https://doaj.org/article/03689adc7ab041fb9113fbe6d497ea8c Revista da Sociedade Brasileira de Medicina Tropical, Vol 44, Iss 1, Pp 4-7 (2011) HIV-1 Transmissão vertical Brasil Arctic medicine. Tropical medicine RC955-962 article 2011 ftdoajarticles https://doi.org/10.1590/S0037-86822011000100002 2022-12-30T23:10:48Z INTRODUCTION: This study aimed to determine the prevalence of vertical HIV-1 transmission in the western region of the State of São Paulo, Brazil. METHODS: The study analyzed the medical records of HIV-1-infected mothers and infant pairs living in the municipalities of São Paulo Regional Health Departments DRS II (Araçatuba) and DRS XI (Presidente Prudente). From March 2001 to March 2006, blood samples were collected and referred to the Molecular Biology Unit of the Adolfo Lutz Institute (ALI), Presidente Prudente. HIV-1-RNA viral load was determined by bDNA assay. RESULTS: The number of births (109/217, 50.2%) and vertical HIV-1 transmissions (6/109, 5.5%) that occurred in DRS II was similar to births (108/217, 49.8%) and vertical transmissions (7/108, 6.5%) in DRS XI (p > 0.05). Although 80% (4/5) of the infected children were male in DRS II, while in DRS XI, 75% (6/8) were female, no differences between sex regarding infected and noninfected children in the regions of Araçatuba and Presidente Prudente were verified. The overall vertical HIV-1 transmission rate was 6%. No consistent reduction in the prevalence of vertical HIV-1 transmission occurred over the years. About 20% of mothers did not know the HIV-1 status of their newborns eight months after delivery. CONCLUSIONS: In the present study, MTCT prevalence rates were about 70% higher than those previously determined in the State of São Paulo, with noreduction throughout the period.Furthermore, a significant number of mothers did not know the HIV-status of their newborns eight months after delivery. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 44 1 4 7 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
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HIV-1 Transmissão vertical Brasil Arctic medicine. Tropical medicine RC955-962 |
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HIV-1 Transmissão vertical Brasil Arctic medicine. Tropical medicine RC955-962 Vera Lúcia Maria Alves Gonçalves Charlene Troiani Armênio Alcântara Ribeiro Patrícia Rodrigues Naufal Spir Elza Keiko Kimura Gushiken Renata Bonfim Vieira Luiz Euribel Prestes-Carneiro Vertical transmission of HIV-1 in the western region of the State of São Paulo |
topic_facet |
HIV-1 Transmissão vertical Brasil Arctic medicine. Tropical medicine RC955-962 |
description |
INTRODUCTION: This study aimed to determine the prevalence of vertical HIV-1 transmission in the western region of the State of São Paulo, Brazil. METHODS: The study analyzed the medical records of HIV-1-infected mothers and infant pairs living in the municipalities of São Paulo Regional Health Departments DRS II (Araçatuba) and DRS XI (Presidente Prudente). From March 2001 to March 2006, blood samples were collected and referred to the Molecular Biology Unit of the Adolfo Lutz Institute (ALI), Presidente Prudente. HIV-1-RNA viral load was determined by bDNA assay. RESULTS: The number of births (109/217, 50.2%) and vertical HIV-1 transmissions (6/109, 5.5%) that occurred in DRS II was similar to births (108/217, 49.8%) and vertical transmissions (7/108, 6.5%) in DRS XI (p > 0.05). Although 80% (4/5) of the infected children were male in DRS II, while in DRS XI, 75% (6/8) were female, no differences between sex regarding infected and noninfected children in the regions of Araçatuba and Presidente Prudente were verified. The overall vertical HIV-1 transmission rate was 6%. No consistent reduction in the prevalence of vertical HIV-1 transmission occurred over the years. About 20% of mothers did not know the HIV-1 status of their newborns eight months after delivery. CONCLUSIONS: In the present study, MTCT prevalence rates were about 70% higher than those previously determined in the State of São Paulo, with noreduction throughout the period.Furthermore, a significant number of mothers did not know the HIV-status of their newborns eight months after delivery. |
format |
Article in Journal/Newspaper |
author |
Vera Lúcia Maria Alves Gonçalves Charlene Troiani Armênio Alcântara Ribeiro Patrícia Rodrigues Naufal Spir Elza Keiko Kimura Gushiken Renata Bonfim Vieira Luiz Euribel Prestes-Carneiro |
author_facet |
Vera Lúcia Maria Alves Gonçalves Charlene Troiani Armênio Alcântara Ribeiro Patrícia Rodrigues Naufal Spir Elza Keiko Kimura Gushiken Renata Bonfim Vieira Luiz Euribel Prestes-Carneiro |
author_sort |
Vera Lúcia Maria Alves Gonçalves |
title |
Vertical transmission of HIV-1 in the western region of the State of São Paulo |
title_short |
Vertical transmission of HIV-1 in the western region of the State of São Paulo |
title_full |
Vertical transmission of HIV-1 in the western region of the State of São Paulo |
title_fullStr |
Vertical transmission of HIV-1 in the western region of the State of São Paulo |
title_full_unstemmed |
Vertical transmission of HIV-1 in the western region of the State of São Paulo |
title_sort |
vertical transmission of hiv-1 in the western region of the state of são paulo |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2011 |
url |
https://doi.org/10.1590/S0037-86822011000100002 https://doaj.org/article/03689adc7ab041fb9113fbe6d497ea8c |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 44, Iss 1, Pp 4-7 (2011) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822011000100002&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/S0037-86822011000100002 https://doaj.org/article/03689adc7ab041fb9113fbe6d497ea8c |
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https://doi.org/10.1590/S0037-86822011000100002 |
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Revista da Sociedade Brasileira de Medicina Tropical |
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44 |
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7 |
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