Sex separation strategies: past experience and new approaches
Abstract The success of the sterile insect technique (SIT) and other genetic strategies designed to eliminate large populations of insects relies on the efficient inundative releases of competitive, sterile males into the natural habitat of the target species. As released sterile females do not cont...
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ftdoajarticles:oai:doaj.org/article:0367c79247cd422990da5e64edf040b4 2023-05-15T15:08:12+02:00 Sex separation strategies: past experience and new approaches Malcolm Colin A Catteruccia Flaminia Benedict Mark Q Bossin Hervé C Papathanos Philippos A Alphey Luke Crisanti Andrea 2009-11-01T00:00:00Z https://doi.org/10.1186/1475-2875-8-S2-S5 https://doaj.org/article/0367c79247cd422990da5e64edf040b4 EN eng BMC http://www.malariajournal.com/content/8/S2/S5 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-8-S2-S5 1475-2875 https://doaj.org/article/0367c79247cd422990da5e64edf040b4 Malaria Journal, Vol 8, Iss Suppl 2, p S5 (2009) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2009 ftdoajarticles https://doi.org/10.1186/1475-2875-8-S2-S5 2022-12-31T08:48:12Z Abstract The success of the sterile insect technique (SIT) and other genetic strategies designed to eliminate large populations of insects relies on the efficient inundative releases of competitive, sterile males into the natural habitat of the target species. As released sterile females do not contribute to the sterility in the field population, systems for the efficient mass production and separation of males from females are needed. For vector species like mosquitoes, in which only females bite and transmit diseases, the thorough removal of females before release while leaving males competent to mate is a stringent prerequisite. Biological, genetic and transgenic approaches have been developed that permit efficient male-female separation for some species considered for SIT. However, most sex separation methods have drawbacks and many of these methods are not directly transferable to mosquitoes. Unlike genetic and transgenic systems, biological methods that rely on sexually dimorphic characters, such as size or development rate, are subject to natural variation, requiring regular adjustment and re-calibration of the sorting systems used. The yield can be improved with the optimization of rearing, but the scale of mass production places practical limits on what is achievable, resulting in a poor rearing to output ratio. High throughput separation is best achieved with scalable genetic or transgenic approaches. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 8 Suppl 2 S5 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Malcolm Colin A Catteruccia Flaminia Benedict Mark Q Bossin Hervé C Papathanos Philippos A Alphey Luke Crisanti Andrea Sex separation strategies: past experience and new approaches |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract The success of the sterile insect technique (SIT) and other genetic strategies designed to eliminate large populations of insects relies on the efficient inundative releases of competitive, sterile males into the natural habitat of the target species. As released sterile females do not contribute to the sterility in the field population, systems for the efficient mass production and separation of males from females are needed. For vector species like mosquitoes, in which only females bite and transmit diseases, the thorough removal of females before release while leaving males competent to mate is a stringent prerequisite. Biological, genetic and transgenic approaches have been developed that permit efficient male-female separation for some species considered for SIT. However, most sex separation methods have drawbacks and many of these methods are not directly transferable to mosquitoes. Unlike genetic and transgenic systems, biological methods that rely on sexually dimorphic characters, such as size or development rate, are subject to natural variation, requiring regular adjustment and re-calibration of the sorting systems used. The yield can be improved with the optimization of rearing, but the scale of mass production places practical limits on what is achievable, resulting in a poor rearing to output ratio. High throughput separation is best achieved with scalable genetic or transgenic approaches. |
format |
Article in Journal/Newspaper |
author |
Malcolm Colin A Catteruccia Flaminia Benedict Mark Q Bossin Hervé C Papathanos Philippos A Alphey Luke Crisanti Andrea |
author_facet |
Malcolm Colin A Catteruccia Flaminia Benedict Mark Q Bossin Hervé C Papathanos Philippos A Alphey Luke Crisanti Andrea |
author_sort |
Malcolm Colin A |
title |
Sex separation strategies: past experience and new approaches |
title_short |
Sex separation strategies: past experience and new approaches |
title_full |
Sex separation strategies: past experience and new approaches |
title_fullStr |
Sex separation strategies: past experience and new approaches |
title_full_unstemmed |
Sex separation strategies: past experience and new approaches |
title_sort |
sex separation strategies: past experience and new approaches |
publisher |
BMC |
publishDate |
2009 |
url |
https://doi.org/10.1186/1475-2875-8-S2-S5 https://doaj.org/article/0367c79247cd422990da5e64edf040b4 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 8, Iss Suppl 2, p S5 (2009) |
op_relation |
http://www.malariajournal.com/content/8/S2/S5 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-8-S2-S5 1475-2875 https://doaj.org/article/0367c79247cd422990da5e64edf040b4 |
op_doi |
https://doi.org/10.1186/1475-2875-8-S2-S5 |
container_title |
Malaria Journal |
container_volume |
8 |
container_issue |
Suppl 2 |
container_start_page |
S5 |
_version_ |
1766339603563806720 |