Experimental Induction of Tenacibaculosis in Atlantic Salmon ( Salmo salar L.) Using Tenacibaculum maritimum , T. dicentrarchi , and T. finnmarkense
There is a limited understanding of the pathogenesis of tenacibaculosis in Atlantic salmon ( Salmo salar L.) and there are few reproducible exposure models for comparison. Atlantic salmon were exposed via bath to Tenacibaculum maritimum , T. dicentrarchi , or T. finnmarkense, and were then grouped w...
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2021
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ftdoajarticles:oai:doaj.org/article:03668a47f58d48098f1cc5bd8c56dbd5 2023-05-15T15:30:28+02:00 Experimental Induction of Tenacibaculosis in Atlantic Salmon ( Salmo salar L.) Using Tenacibaculum maritimum , T. dicentrarchi , and T. finnmarkense Joseph P. Nowlan Scott R. Britney John S. Lumsden Spencer Russell 2021-11-01T00:00:00Z https://doi.org/10.3390/pathogens10111439 https://doaj.org/article/03668a47f58d48098f1cc5bd8c56dbd5 EN eng MDPI AG https://www.mdpi.com/2076-0817/10/11/1439 https://doaj.org/toc/2076-0817 doi:10.3390/pathogens10111439 2076-0817 https://doaj.org/article/03668a47f58d48098f1cc5bd8c56dbd5 Pathogens, Vol 10, Iss 1439, p 1439 (2021) aquaculture tenacibaculosis mouthrot bath-exposure dysbiosis histopathology Medicine R article 2021 ftdoajarticles https://doi.org/10.3390/pathogens10111439 2022-12-30T20:08:12Z There is a limited understanding of the pathogenesis of tenacibaculosis in Atlantic salmon ( Salmo salar L.) and there are few reproducible exposure models for comparison. Atlantic salmon were exposed via bath to Tenacibaculum maritimum , T. dicentrarchi , or T. finnmarkense, and were then grouped with naïve cohabitants. Mortalities had exaggerated clinical signs of mouthrot, a presentation of tenacibaculosis characterized by epidermal ulceration and yellow plaques, on the mouth and less frequently on other tissues. Histopathology showed tissue spongiosis, erosion, ulceration, and necrosis ranging from mild to marked, locally to regionally extensive with mats of intralesional bacteria on the rostrum, vomer, gill rakers, gill filaments, and body surface. Exposure to T. maritimum resulted in less than a 0.4 probability of survival for both exposed and cohabitants until Day 21. Exposures to T. dicentrarchi resulted in 0 and 0.55 (exposed), and 0.8 and 0.9 (cohabitant) probability of survival to Day 12 post-exposure, while T. finnmarkense had a 0.9 probability of survival to Day 12 for all groups. This experimental infection model will be useful to further investigate the pathogenesis of tenacibaculosis, its treatment, and immunity to Tenacibaculum species. Article in Journal/Newspaper Atlantic salmon Salmo salar Directory of Open Access Journals: DOAJ Articles Pathogens 10 11 1439 |
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Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
aquaculture tenacibaculosis mouthrot bath-exposure dysbiosis histopathology Medicine R |
spellingShingle |
aquaculture tenacibaculosis mouthrot bath-exposure dysbiosis histopathology Medicine R Joseph P. Nowlan Scott R. Britney John S. Lumsden Spencer Russell Experimental Induction of Tenacibaculosis in Atlantic Salmon ( Salmo salar L.) Using Tenacibaculum maritimum , T. dicentrarchi , and T. finnmarkense |
topic_facet |
aquaculture tenacibaculosis mouthrot bath-exposure dysbiosis histopathology Medicine R |
description |
There is a limited understanding of the pathogenesis of tenacibaculosis in Atlantic salmon ( Salmo salar L.) and there are few reproducible exposure models for comparison. Atlantic salmon were exposed via bath to Tenacibaculum maritimum , T. dicentrarchi , or T. finnmarkense, and were then grouped with naïve cohabitants. Mortalities had exaggerated clinical signs of mouthrot, a presentation of tenacibaculosis characterized by epidermal ulceration and yellow plaques, on the mouth and less frequently on other tissues. Histopathology showed tissue spongiosis, erosion, ulceration, and necrosis ranging from mild to marked, locally to regionally extensive with mats of intralesional bacteria on the rostrum, vomer, gill rakers, gill filaments, and body surface. Exposure to T. maritimum resulted in less than a 0.4 probability of survival for both exposed and cohabitants until Day 21. Exposures to T. dicentrarchi resulted in 0 and 0.55 (exposed), and 0.8 and 0.9 (cohabitant) probability of survival to Day 12 post-exposure, while T. finnmarkense had a 0.9 probability of survival to Day 12 for all groups. This experimental infection model will be useful to further investigate the pathogenesis of tenacibaculosis, its treatment, and immunity to Tenacibaculum species. |
format |
Article in Journal/Newspaper |
author |
Joseph P. Nowlan Scott R. Britney John S. Lumsden Spencer Russell |
author_facet |
Joseph P. Nowlan Scott R. Britney John S. Lumsden Spencer Russell |
author_sort |
Joseph P. Nowlan |
title |
Experimental Induction of Tenacibaculosis in Atlantic Salmon ( Salmo salar L.) Using Tenacibaculum maritimum , T. dicentrarchi , and T. finnmarkense |
title_short |
Experimental Induction of Tenacibaculosis in Atlantic Salmon ( Salmo salar L.) Using Tenacibaculum maritimum , T. dicentrarchi , and T. finnmarkense |
title_full |
Experimental Induction of Tenacibaculosis in Atlantic Salmon ( Salmo salar L.) Using Tenacibaculum maritimum , T. dicentrarchi , and T. finnmarkense |
title_fullStr |
Experimental Induction of Tenacibaculosis in Atlantic Salmon ( Salmo salar L.) Using Tenacibaculum maritimum , T. dicentrarchi , and T. finnmarkense |
title_full_unstemmed |
Experimental Induction of Tenacibaculosis in Atlantic Salmon ( Salmo salar L.) Using Tenacibaculum maritimum , T. dicentrarchi , and T. finnmarkense |
title_sort |
experimental induction of tenacibaculosis in atlantic salmon ( salmo salar l.) using tenacibaculum maritimum , t. dicentrarchi , and t. finnmarkense |
publisher |
MDPI AG |
publishDate |
2021 |
url |
https://doi.org/10.3390/pathogens10111439 https://doaj.org/article/03668a47f58d48098f1cc5bd8c56dbd5 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
Pathogens, Vol 10, Iss 1439, p 1439 (2021) |
op_relation |
https://www.mdpi.com/2076-0817/10/11/1439 https://doaj.org/toc/2076-0817 doi:10.3390/pathogens10111439 2076-0817 https://doaj.org/article/03668a47f58d48098f1cc5bd8c56dbd5 |
op_doi |
https://doi.org/10.3390/pathogens10111439 |
container_title |
Pathogens |
container_volume |
10 |
container_issue |
11 |
container_start_page |
1439 |
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1766360919255810048 |