Citrus peel extract and powder attenuate hypercholesterolemia and hyperglycemia using rodent experimental modeling
Objective: To investigate hypocholesterolemic and hypoglycemic potential of citrus peel extract and powder using rodent experimental modeling. Methods: Considering the fact, rat feeding trial was carried out for a period of 56 d to access the prophylaxis of citrus peel flavonoids by employing normal...
Published in: | Asian Pacific Journal of Tropical Biomedicine |
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Wolters Kluwer Medknow Publications
2017
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ftdoajarticles:oai:doaj.org/article:0119de96a8414753845d637601de1d51 2023-05-15T15:06:33+02:00 Citrus peel extract and powder attenuate hypercholesterolemia and hyperglycemia using rodent experimental modeling Humaira Ashraf Masood Sadiq Butt Muhammad Jawad Iqbal Hafiz Ansar Rasul Suleria 2017-10-01T00:00:00Z https://doi.org/10.1016/j.apjtb.2017.09.012 https://doaj.org/article/0119de96a8414753845d637601de1d51 EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169117309784 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2017.09.012 https://doaj.org/article/0119de96a8414753845d637601de1d51 Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 10, Pp 870-880 (2017) Functional foods Nutraceutical Citrus powder Hypercholesterolemia Hyperglycemia Efficacy study Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2017 ftdoajarticles https://doi.org/10.1016/j.apjtb.2017.09.012 2022-12-30T22:01:50Z Objective: To investigate hypocholesterolemic and hypoglycemic potential of citrus peel extract and powder using rodent experimental modeling. Methods: Considering the fact, rat feeding trial was carried out for a period of 56 d to access the prophylaxis of citrus peel flavonoids by employing normal (study I), hyperglycemic (study II) and hypercholesterolemic (study III) rats. Each study was further divided into three groups to ensure the provision of selected diets, i.e., control, functional and nutraceutical diets. Each study was further divided into three groups to ensure the provision of selected diets, i.e., control, functional and nutraceutical diets. Results: Declining trend for total cholesterol was observed in all studies with maximum reduction (8.55%) in rat group fed on nutraceutical diet in study III. Likewise, levels of low density lipoproteins and triglycerides reduced 11.39% and 7.89% respectively in hypercholesterolemic rats. Moreover, nutraceutical diet alleviated the sera glucose level by 8.96% in study II. Conclusions: Conclusively, inclusion of citrus peel bioflavonoids in dietary therapies is a promising strategy to modulate lipidemic and glycemic attributes without imparting any deleterious effect on hematological parameters. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Biomedicine 7 10 870 880 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Functional foods Nutraceutical Citrus powder Hypercholesterolemia Hyperglycemia Efficacy study Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
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Functional foods Nutraceutical Citrus powder Hypercholesterolemia Hyperglycemia Efficacy study Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Humaira Ashraf Masood Sadiq Butt Muhammad Jawad Iqbal Hafiz Ansar Rasul Suleria Citrus peel extract and powder attenuate hypercholesterolemia and hyperglycemia using rodent experimental modeling |
topic_facet |
Functional foods Nutraceutical Citrus powder Hypercholesterolemia Hyperglycemia Efficacy study Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Objective: To investigate hypocholesterolemic and hypoglycemic potential of citrus peel extract and powder using rodent experimental modeling. Methods: Considering the fact, rat feeding trial was carried out for a period of 56 d to access the prophylaxis of citrus peel flavonoids by employing normal (study I), hyperglycemic (study II) and hypercholesterolemic (study III) rats. Each study was further divided into three groups to ensure the provision of selected diets, i.e., control, functional and nutraceutical diets. Each study was further divided into three groups to ensure the provision of selected diets, i.e., control, functional and nutraceutical diets. Results: Declining trend for total cholesterol was observed in all studies with maximum reduction (8.55%) in rat group fed on nutraceutical diet in study III. Likewise, levels of low density lipoproteins and triglycerides reduced 11.39% and 7.89% respectively in hypercholesterolemic rats. Moreover, nutraceutical diet alleviated the sera glucose level by 8.96% in study II. Conclusions: Conclusively, inclusion of citrus peel bioflavonoids in dietary therapies is a promising strategy to modulate lipidemic and glycemic attributes without imparting any deleterious effect on hematological parameters. |
format |
Article in Journal/Newspaper |
author |
Humaira Ashraf Masood Sadiq Butt Muhammad Jawad Iqbal Hafiz Ansar Rasul Suleria |
author_facet |
Humaira Ashraf Masood Sadiq Butt Muhammad Jawad Iqbal Hafiz Ansar Rasul Suleria |
author_sort |
Humaira Ashraf |
title |
Citrus peel extract and powder attenuate hypercholesterolemia and hyperglycemia using rodent experimental modeling |
title_short |
Citrus peel extract and powder attenuate hypercholesterolemia and hyperglycemia using rodent experimental modeling |
title_full |
Citrus peel extract and powder attenuate hypercholesterolemia and hyperglycemia using rodent experimental modeling |
title_fullStr |
Citrus peel extract and powder attenuate hypercholesterolemia and hyperglycemia using rodent experimental modeling |
title_full_unstemmed |
Citrus peel extract and powder attenuate hypercholesterolemia and hyperglycemia using rodent experimental modeling |
title_sort |
citrus peel extract and powder attenuate hypercholesterolemia and hyperglycemia using rodent experimental modeling |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2017 |
url |
https://doi.org/10.1016/j.apjtb.2017.09.012 https://doaj.org/article/0119de96a8414753845d637601de1d51 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 10, Pp 870-880 (2017) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169117309784 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2017.09.012 https://doaj.org/article/0119de96a8414753845d637601de1d51 |
op_doi |
https://doi.org/10.1016/j.apjtb.2017.09.012 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
7 |
container_issue |
10 |
container_start_page |
870 |
op_container_end_page |
880 |
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1766338129497686016 |