Fonsecaea pedrosoi cerebral phaeohyphomycosis ("chromoblastomycosis"): first human culture-proven case reported in Brazil
Cerebral phaeohyphomycosis ("chromoblastomycosis") is a rare intracranial lesion. We report the first human culture-proven case of brain abscesses due to Fonsecaea pedrosoi in Brazil. The patient, a 28 year-old immunocompetent white male, had ocular manifestations and a hypertensive intrac...
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ftdoajarticles:oai:doaj.org/article:00f5fe0ae3684c489c5813ca91f2403b 2024-09-09T19:26:32+00:00 Fonsecaea pedrosoi cerebral phaeohyphomycosis ("chromoblastomycosis"): first human culture-proven case reported in Brazil José Paulo S. Nóbrega Sergio Rosemberg Ana Maria Adami Elizabeth Maria Heins-Vaccari Carlos da Silva Lacaz Thales de Brito 2003-08-01T00:00:00Z https://doaj.org/article/00f5fe0ae3684c489c5813ca91f2403b EN eng Universidade de São Paulo (USP) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652003000400008&tlng=en https://doaj.org/toc/1678-9946 1678-9946 https://doaj.org/article/00f5fe0ae3684c489c5813ca91f2403b Revista do Instituto de Medicina Tropical de São Paulo, Vol 45, Iss 4, Pp 217-220 (2003) Phaeohyphomycosis Cerebral "chromoblastomycosis" Fonsecae pedrosoi Brazil Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2003 ftdoajarticles 2024-08-05T17:49:30Z Cerebral phaeohyphomycosis ("chromoblastomycosis") is a rare intracranial lesion. We report the first human culture-proven case of brain abscesses due to Fonsecaea pedrosoi in Brazil. The patient, a 28 year-old immunocompetent white male, had ocular manifestations and a hypertensive intracranial syndrome. Magnetic resonance imaging (MRI) of the brain revealed a main tumoral mass involving the right temporo-occipital area and another smaller apparently healed lesion at the left occipital lobe. A cerebral biopsy was performed and the pathological report was cerebral chromoblastomycosis. The main lesion was enucleated surgically and culture of the necrotic and suppurative mass grew a fungus identified as Fonsecaea pedrosoi. The patient had received a knife wound sixteen years prior to his hospitalization and, more recently, manifested a pulmonary granulomatous lesion in the right lung with a single non-pigmented form of a fungus present. It was speculated that the fungus might have gained entrance to the host through the skin lesion, although a primary respiratory lesion was not excluded. The patient was discharged from the hospital still with ocular manifestations and on antimycotic therapy and was followed for eight months without disease recurrence. Few months after he had complications of the previous neuro-surgery and died. A complete autopsy was performed and no residual fungal disease was found. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
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Phaeohyphomycosis Cerebral "chromoblastomycosis" Fonsecae pedrosoi Brazil Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Phaeohyphomycosis Cerebral "chromoblastomycosis" Fonsecae pedrosoi Brazil Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 José Paulo S. Nóbrega Sergio Rosemberg Ana Maria Adami Elizabeth Maria Heins-Vaccari Carlos da Silva Lacaz Thales de Brito Fonsecaea pedrosoi cerebral phaeohyphomycosis ("chromoblastomycosis"): first human culture-proven case reported in Brazil |
topic_facet |
Phaeohyphomycosis Cerebral "chromoblastomycosis" Fonsecae pedrosoi Brazil Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Cerebral phaeohyphomycosis ("chromoblastomycosis") is a rare intracranial lesion. We report the first human culture-proven case of brain abscesses due to Fonsecaea pedrosoi in Brazil. The patient, a 28 year-old immunocompetent white male, had ocular manifestations and a hypertensive intracranial syndrome. Magnetic resonance imaging (MRI) of the brain revealed a main tumoral mass involving the right temporo-occipital area and another smaller apparently healed lesion at the left occipital lobe. A cerebral biopsy was performed and the pathological report was cerebral chromoblastomycosis. The main lesion was enucleated surgically and culture of the necrotic and suppurative mass grew a fungus identified as Fonsecaea pedrosoi. The patient had received a knife wound sixteen years prior to his hospitalization and, more recently, manifested a pulmonary granulomatous lesion in the right lung with a single non-pigmented form of a fungus present. It was speculated that the fungus might have gained entrance to the host through the skin lesion, although a primary respiratory lesion was not excluded. The patient was discharged from the hospital still with ocular manifestations and on antimycotic therapy and was followed for eight months without disease recurrence. Few months after he had complications of the previous neuro-surgery and died. A complete autopsy was performed and no residual fungal disease was found. |
format |
Article in Journal/Newspaper |
author |
José Paulo S. Nóbrega Sergio Rosemberg Ana Maria Adami Elizabeth Maria Heins-Vaccari Carlos da Silva Lacaz Thales de Brito |
author_facet |
José Paulo S. Nóbrega Sergio Rosemberg Ana Maria Adami Elizabeth Maria Heins-Vaccari Carlos da Silva Lacaz Thales de Brito |
author_sort |
José Paulo S. Nóbrega |
title |
Fonsecaea pedrosoi cerebral phaeohyphomycosis ("chromoblastomycosis"): first human culture-proven case reported in Brazil |
title_short |
Fonsecaea pedrosoi cerebral phaeohyphomycosis ("chromoblastomycosis"): first human culture-proven case reported in Brazil |
title_full |
Fonsecaea pedrosoi cerebral phaeohyphomycosis ("chromoblastomycosis"): first human culture-proven case reported in Brazil |
title_fullStr |
Fonsecaea pedrosoi cerebral phaeohyphomycosis ("chromoblastomycosis"): first human culture-proven case reported in Brazil |
title_full_unstemmed |
Fonsecaea pedrosoi cerebral phaeohyphomycosis ("chromoblastomycosis"): first human culture-proven case reported in Brazil |
title_sort |
fonsecaea pedrosoi cerebral phaeohyphomycosis ("chromoblastomycosis"): first human culture-proven case reported in brazil |
publisher |
Universidade de São Paulo (USP) |
publishDate |
2003 |
url |
https://doaj.org/article/00f5fe0ae3684c489c5813ca91f2403b |
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Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista do Instituto de Medicina Tropical de São Paulo, Vol 45, Iss 4, Pp 217-220 (2003) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652003000400008&tlng=en https://doaj.org/toc/1678-9946 1678-9946 https://doaj.org/article/00f5fe0ae3684c489c5813ca91f2403b |
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1809896133180260352 |