Paracoccidioidomycosis in a western Brazilian Amazon State: Clinical-epidemiologic profile and spatial distribution of the disease
Introduction: Paracoccidioidomycosis (PCM) is a systemic infection caused by the fungus Paracoccidioides brasiliensis. PCM is considered one of the most important systemic mycoses in Latin America. Methods: This is a clinical, epidemiological, retrospective, quantitative study of PCM cases in patien...
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Online Access: | https://doi.org/10.1590/0037-8682-0225-2013 https://doaj.org/article/00b28505e6e24777a107a2df9a2dade9 |
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ftdoajarticles:oai:doaj.org/article:00b28505e6e24777a107a2df9a2dade9 2023-05-15T15:10:59+02:00 Paracoccidioidomycosis in a western Brazilian Amazon State: Clinical-epidemiologic profile and spatial distribution of the disease Gabriel de Deus Vieira Thaianne da Cunha Alves Sônia Maria Dias de Lima Luís Marcelo Aranha Camargo Camila Maciel de Sousa 2014-01-01T00:00:00Z https://doi.org/10.1590/0037-8682-0225-2013 https://doaj.org/article/00b28505e6e24777a107a2df9a2dade9 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000100063&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0225-2013 https://doaj.org/article/00b28505e6e24777a107a2df9a2dade9 Revista da Sociedade Brasileira de Medicina Tropical, Vol 47, Iss 1, Pp 63-68 (2014) Paracoccidioidomycosis Fungal infection Epidemiology Arctic medicine. Tropical medicine RC955-962 article 2014 ftdoajarticles https://doi.org/10.1590/0037-8682-0225-2013 2022-12-31T02:46:32Z Introduction: Paracoccidioidomycosis (PCM) is a systemic infection caused by the fungus Paracoccidioides brasiliensis. PCM is considered one of the most important systemic mycoses in Latin America. Methods: This is a clinical, epidemiological, retrospective, quantitative study of PCM cases in patients attending the National Health Service in the State of Rondônia in 1997-2012. The examined variables included sex, age group, year of diagnosis, education level, profession, place of residence, diagnostic test, prior treatment, medication used, comorbidities and case progress. Results: During the study period, 2,163 PCM cases were registered in Rondônia, and the mean annual incidence was 9.4/100,000 people. The municipalities with the highest rates were located in the southeastern region of Rondônia, and the towns of Pimenteiras do Oeste and Espigão do Oeste had the highest rates in the state, which were 39.1/100,000 and 37.4/100,000 people, respectively. Among all cases, 90.2% and 9.8% were observed in men and women, respectively, and most cases (58.2%) were observed in patients aged between 40 and 59 years. Itraconazole was used to treat 91.6% (1,771) of cases, followed by sulfamethoxazole in combination with trimethoprim (4.4% [85] of cases). One hundred thirty-one (6%) patients died. Conclusions: The State of Rondônia has a high incidence of PCM, and the municipalities in the southeastern region of the state were found to have the highest incidence rates of this disease. Our findings suggest that Rondônia is the state in the northern region with the highest mortality rate for PCM. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 47 1 63 68 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Paracoccidioidomycosis Fungal infection Epidemiology Arctic medicine. Tropical medicine RC955-962 |
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Paracoccidioidomycosis Fungal infection Epidemiology Arctic medicine. Tropical medicine RC955-962 Gabriel de Deus Vieira Thaianne da Cunha Alves Sônia Maria Dias de Lima Luís Marcelo Aranha Camargo Camila Maciel de Sousa Paracoccidioidomycosis in a western Brazilian Amazon State: Clinical-epidemiologic profile and spatial distribution of the disease |
topic_facet |
Paracoccidioidomycosis Fungal infection Epidemiology Arctic medicine. Tropical medicine RC955-962 |
description |
Introduction: Paracoccidioidomycosis (PCM) is a systemic infection caused by the fungus Paracoccidioides brasiliensis. PCM is considered one of the most important systemic mycoses in Latin America. Methods: This is a clinical, epidemiological, retrospective, quantitative study of PCM cases in patients attending the National Health Service in the State of Rondônia in 1997-2012. The examined variables included sex, age group, year of diagnosis, education level, profession, place of residence, diagnostic test, prior treatment, medication used, comorbidities and case progress. Results: During the study period, 2,163 PCM cases were registered in Rondônia, and the mean annual incidence was 9.4/100,000 people. The municipalities with the highest rates were located in the southeastern region of Rondônia, and the towns of Pimenteiras do Oeste and Espigão do Oeste had the highest rates in the state, which were 39.1/100,000 and 37.4/100,000 people, respectively. Among all cases, 90.2% and 9.8% were observed in men and women, respectively, and most cases (58.2%) were observed in patients aged between 40 and 59 years. Itraconazole was used to treat 91.6% (1,771) of cases, followed by sulfamethoxazole in combination with trimethoprim (4.4% [85] of cases). One hundred thirty-one (6%) patients died. Conclusions: The State of Rondônia has a high incidence of PCM, and the municipalities in the southeastern region of the state were found to have the highest incidence rates of this disease. Our findings suggest that Rondônia is the state in the northern region with the highest mortality rate for PCM. |
format |
Article in Journal/Newspaper |
author |
Gabriel de Deus Vieira Thaianne da Cunha Alves Sônia Maria Dias de Lima Luís Marcelo Aranha Camargo Camila Maciel de Sousa |
author_facet |
Gabriel de Deus Vieira Thaianne da Cunha Alves Sônia Maria Dias de Lima Luís Marcelo Aranha Camargo Camila Maciel de Sousa |
author_sort |
Gabriel de Deus Vieira |
title |
Paracoccidioidomycosis in a western Brazilian Amazon State: Clinical-epidemiologic profile and spatial distribution of the disease |
title_short |
Paracoccidioidomycosis in a western Brazilian Amazon State: Clinical-epidemiologic profile and spatial distribution of the disease |
title_full |
Paracoccidioidomycosis in a western Brazilian Amazon State: Clinical-epidemiologic profile and spatial distribution of the disease |
title_fullStr |
Paracoccidioidomycosis in a western Brazilian Amazon State: Clinical-epidemiologic profile and spatial distribution of the disease |
title_full_unstemmed |
Paracoccidioidomycosis in a western Brazilian Amazon State: Clinical-epidemiologic profile and spatial distribution of the disease |
title_sort |
paracoccidioidomycosis in a western brazilian amazon state: clinical-epidemiologic profile and spatial distribution of the disease |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2014 |
url |
https://doi.org/10.1590/0037-8682-0225-2013 https://doaj.org/article/00b28505e6e24777a107a2df9a2dade9 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 47, Iss 1, Pp 63-68 (2014) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000100063&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0225-2013 https://doaj.org/article/00b28505e6e24777a107a2df9a2dade9 |
op_doi |
https://doi.org/10.1590/0037-8682-0225-2013 |
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Revista da Sociedade Brasileira de Medicina Tropical |
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47 |
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63 |
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68 |
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