Diagnosing and staging of cystic echinococcosis: how do CT and MRI perform in comparison to ultrasound?
BACKGROUND: Imaging plays the key role in diagnosing and staging of CE. The description of CE-specific imaging features and the WHO CE cyst classification is based on ultrasound. The reproducibility of the ultrasound-defined features of CE cysts is variable in MR- and CT-imaging. This is of particul...
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ftdoajarticles:oai:doaj.org/article:005a3eb392b94496902c94777cf3d67e 2023-05-15T15:12:52+02:00 Diagnosing and staging of cystic echinococcosis: how do CT and MRI perform in comparison to ultrasound? Marija Stojkovic Kerstin Rosenberger Hans-Ullrich Kauczor Thomas Junghanss Waldemar Hosch 2012-01-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0001880 https://doaj.org/article/005a3eb392b94496902c94777cf3d67e EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC3493391?pdf=render https://doaj.org/toc/1935-2735 1935-2735 doi:10.1371/journal.pntd.0001880 https://doaj.org/article/005a3eb392b94496902c94777cf3d67e PLoS Neglected Tropical Diseases, Vol 6, Iss 10, p e1880 (2012) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2012 ftdoajarticles https://doi.org/10.1371/journal.pntd.0001880 2022-12-31T13:20:58Z BACKGROUND: Imaging plays the key role in diagnosing and staging of CE. The description of CE-specific imaging features and the WHO CE cyst classification is based on ultrasound. The reproducibility of the ultrasound-defined features of CE cysts is variable in MR- and CT-imaging. This is of particular importance for cysts that are not accessible by US and because of the increasing availability and overuse of CT and MR imaging. METHODOLOGY/PRINCIPAL FINDINGS: Retrospective analysis of patients with abdominal CE cysts of an interdisciplinary CE clinic who had CT and/or MRI scans performed additionally to US imaging. All images were read and interpreted by the same senior radiologist experienced in the diagnosis of CE. US, CT and MR images were staged according to the WHO classification criteria. The agreement beyond chance was quantified by kappa coefficients (κ). 107 patients with 187 CE cysts met the inclusion criteria. All cysts were assessed by US, 138 by CT, and 125 by MRI. The level of agreement beyond chance of the individual CE stages 1-4 was clearly lower for CT, with κ ranging from 0.62 to 0.72, compared to MRI with values of κ between 0.83 and 1.0. For CE5 cysts CT (κ = 0.95) performed better than MRI (κ = 0.65). CONCLUSIONS: Ultrasound remains the corner stone of diagnosis, staging and follow up of CE cysts. MRI reproduces the ultrasound-defined features of CE better than CT. If US cannot be performed due to cyst location or patient-specific reasons MRI with heavily T2-weighted series is preferable to CT. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLoS Neglected Tropical Diseases 6 10 e1880 |
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Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Marija Stojkovic Kerstin Rosenberger Hans-Ullrich Kauczor Thomas Junghanss Waldemar Hosch Diagnosing and staging of cystic echinococcosis: how do CT and MRI perform in comparison to ultrasound? |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
BACKGROUND: Imaging plays the key role in diagnosing and staging of CE. The description of CE-specific imaging features and the WHO CE cyst classification is based on ultrasound. The reproducibility of the ultrasound-defined features of CE cysts is variable in MR- and CT-imaging. This is of particular importance for cysts that are not accessible by US and because of the increasing availability and overuse of CT and MR imaging. METHODOLOGY/PRINCIPAL FINDINGS: Retrospective analysis of patients with abdominal CE cysts of an interdisciplinary CE clinic who had CT and/or MRI scans performed additionally to US imaging. All images were read and interpreted by the same senior radiologist experienced in the diagnosis of CE. US, CT and MR images were staged according to the WHO classification criteria. The agreement beyond chance was quantified by kappa coefficients (κ). 107 patients with 187 CE cysts met the inclusion criteria. All cysts were assessed by US, 138 by CT, and 125 by MRI. The level of agreement beyond chance of the individual CE stages 1-4 was clearly lower for CT, with κ ranging from 0.62 to 0.72, compared to MRI with values of κ between 0.83 and 1.0. For CE5 cysts CT (κ = 0.95) performed better than MRI (κ = 0.65). CONCLUSIONS: Ultrasound remains the corner stone of diagnosis, staging and follow up of CE cysts. MRI reproduces the ultrasound-defined features of CE better than CT. If US cannot be performed due to cyst location or patient-specific reasons MRI with heavily T2-weighted series is preferable to CT. |
format |
Article in Journal/Newspaper |
author |
Marija Stojkovic Kerstin Rosenberger Hans-Ullrich Kauczor Thomas Junghanss Waldemar Hosch |
author_facet |
Marija Stojkovic Kerstin Rosenberger Hans-Ullrich Kauczor Thomas Junghanss Waldemar Hosch |
author_sort |
Marija Stojkovic |
title |
Diagnosing and staging of cystic echinococcosis: how do CT and MRI perform in comparison to ultrasound? |
title_short |
Diagnosing and staging of cystic echinococcosis: how do CT and MRI perform in comparison to ultrasound? |
title_full |
Diagnosing and staging of cystic echinococcosis: how do CT and MRI perform in comparison to ultrasound? |
title_fullStr |
Diagnosing and staging of cystic echinococcosis: how do CT and MRI perform in comparison to ultrasound? |
title_full_unstemmed |
Diagnosing and staging of cystic echinococcosis: how do CT and MRI perform in comparison to ultrasound? |
title_sort |
diagnosing and staging of cystic echinococcosis: how do ct and mri perform in comparison to ultrasound? |
publisher |
Public Library of Science (PLoS) |
publishDate |
2012 |
url |
https://doi.org/10.1371/journal.pntd.0001880 https://doaj.org/article/005a3eb392b94496902c94777cf3d67e |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 6, Iss 10, p e1880 (2012) |
op_relation |
http://europepmc.org/articles/PMC3493391?pdf=render https://doaj.org/toc/1935-2735 1935-2735 doi:10.1371/journal.pntd.0001880 https://doaj.org/article/005a3eb392b94496902c94777cf3d67e |
op_doi |
https://doi.org/10.1371/journal.pntd.0001880 |
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PLoS Neglected Tropical Diseases |
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6 |
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10 |
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e1880 |
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