Translation from Microgravity Research to Earth Application

• Published in: International Journal of Molecular Sciences
• Main Authors: Grimm, Daniela, Hemmersbach, Ruth
• Format: Other Non-Article Part of Journal/Newspaper
• Language: English
• Published: Multidisciplinary Digital Publishing Institute (MDPI) 2022
• Subjects: Gravitationsbiologie; Antarc*; Antarctica
• Online Access: https://elib.dlr.de/189011/; https://elib.dlr.de/189011/1/ijms-23-10995.pdf; https://www.mdpi.com/1422-0067/23/19/10995

The topic Translation from Microgravity Research to Earth Application comprises publications focusing on space life sciences, gravitational biology and space medicine. It covers publications reporting the impact of altered environmental conditions, such as microgravity (µg), cosmic radiation and isolation on organisms down to the level of cells. In addition, the topic collects studies validating causal diagrams of human health risks for spaceflight, hypergravity studies and investigations about the impact of extreme isolation in the Antarctica on the human body. µg provides a unique research environment and an opportunity to identify the mechanism of gravity-sensing and related signaling pathways, regulation and adaptation responses at the cellular, tissue and organism level, covering animals, plants and humans. µg-research is supported and validated by ground-based studies in µg-analogues and simulations, as well as under increased gravitational (hypergravity) conditions, providing comprehensive and new knowledge on the regulation of cellular and subcellular functioning.