Efecto hepatoprotector de vaccinium floribundum hbk “pushgay” (ericaceae) frente al estrés oxidativo inducido con tetracloruro de carbono
The hydroalcoholic extract of the fruit of Vaccinium floribundum HBK "pushgay" was tested in Rattus rattus variety albinus to determine its hepatoprotective effect against oxidative stress induced by carbon tetrachloride. We worked with 20 rats divided into four groups: negative control, w...
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Format: | Article in Journal/Newspaper |
Language: | Spanish |
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2015
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Online Access: | https://dialnet.unirioja.es/servlet/oaiart?codigo=9397856 |
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ftdialnet:oai:dialnet.unirioja.es:ART0001663412 |
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institution |
Open Polar |
collection |
Dialnet - Portada de revistas (Universidad de La Rioja) |
op_collection_id |
ftdialnet |
language |
Spanish |
topic |
Vaccinium floribundum hepatoprotector tetracloruro de carbono estrés oxidativo hepatoprotective carbon tetrachloride oxidative stress |
spellingShingle |
Vaccinium floribundum hepatoprotector tetracloruro de carbono estrés oxidativo hepatoprotective carbon tetrachloride oxidative stress Medina R., Carmen Pretel, Orlando Urquiaga, Tito Torres, Patricia Villanueva, Carmen Efecto hepatoprotector de vaccinium floribundum hbk “pushgay” (ericaceae) frente al estrés oxidativo inducido con tetracloruro de carbono |
topic_facet |
Vaccinium floribundum hepatoprotector tetracloruro de carbono estrés oxidativo hepatoprotective carbon tetrachloride oxidative stress |
description |
The hydroalcoholic extract of the fruit of Vaccinium floribundum HBK "pushgay" was tested in Rattus rattus variety albinus to determine its hepatoprotective effect against oxidative stress induced by carbon tetrachloride. We worked with 20 rats divided into four groups: negative control, which was inoculated for seven days via orogastric tube, sterile physiological saline (SSFE); positive control, which was inoculated two days via orogastric tube, carbon tetrachloride 1 mL·Kg-1 body weight and then by five consecutive days SSFE and experimental, consisting of two groups, which were inoculated, via orogastric tube, carbon tetrachloride 1mL·Kg-1 body weight for two days and then for five consecutive days, the hydroalcoholic extract of Vaccinium floribundum at concentrations of 300 mg·Kg-1 body weight and 600 mg·Kg-1 body weight each group respectively. The concentration of free radicals in liver was determined in all groups by the method of thiobarbituric acid reactive substances; also, histological sections were performed to evaluate the hepatoprotective effect of the hydroalcoholic extract. The average concentrations of free radicals determined in the negative control groups, positivecontrol, and experimental with 300 mg of the hydroalcoholic extract·Kg-1 body weight and 600mg of the hydroalcoholic extract·Kg-1 body weight were, respectively: 6.149; 14.466; 11.794 and 8.786 μg of malondialdehyde.g-1of liver, showing statistically significant differences between the groups (P<0.05). It was determined that the group treated with carbon tetrachloride over thehydroalcoholic extract 600 mg·kg-1 body weight, decreased significantly the amount of free radicals and favored the rapid liver regeneration. El extracto hidroalcohólico del fruto de Vaccinium floribundum HBK “pushgay” fue ensayado en Rattus rattus variedad albinus para determinar su efecto hepatoprotector frente al estrés oxidativo inducido con tetracloruro de carbono. Se trabajó con 20 ratas distribuidas en cuatro grupos: control negativo, al cual se le ... |
format |
Article in Journal/Newspaper |
author |
Medina R., Carmen Pretel, Orlando Urquiaga, Tito Torres, Patricia Villanueva, Carmen |
author_facet |
Medina R., Carmen Pretel, Orlando Urquiaga, Tito Torres, Patricia Villanueva, Carmen |
author_sort |
Medina R., Carmen |
title |
Efecto hepatoprotector de vaccinium floribundum hbk “pushgay” (ericaceae) frente al estrés oxidativo inducido con tetracloruro de carbono |
title_short |
Efecto hepatoprotector de vaccinium floribundum hbk “pushgay” (ericaceae) frente al estrés oxidativo inducido con tetracloruro de carbono |
title_full |
Efecto hepatoprotector de vaccinium floribundum hbk “pushgay” (ericaceae) frente al estrés oxidativo inducido con tetracloruro de carbono |
title_fullStr |
Efecto hepatoprotector de vaccinium floribundum hbk “pushgay” (ericaceae) frente al estrés oxidativo inducido con tetracloruro de carbono |
title_full_unstemmed |
Efecto hepatoprotector de vaccinium floribundum hbk “pushgay” (ericaceae) frente al estrés oxidativo inducido con tetracloruro de carbono |
title_sort |
efecto hepatoprotector de vaccinium floribundum hbk “pushgay” (ericaceae) frente al estrés oxidativo inducido con tetracloruro de carbono |
publishDate |
2015 |
url |
https://dialnet.unirioja.es/servlet/oaiart?codigo=9397856 |
genre |
Rattus rattus |
genre_facet |
Rattus rattus |
op_source |
The Biologist, ISSN 1816-0719, Vol. 13, Nº. 2, 2015 (Ejemplar dedicado a: The Biologist), pags. 235-247 |
op_relation |
https://dialnet.unirioja.es/servlet/oaiart?codigo=9397856 (Revista) ISSN 1994-9073 (Revista) ISSN 1816-0719 |
op_rights |
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ftdialnet:oai:dialnet.unirioja.es:ART0001663412 2024-04-28T08:36:58+00:00 Efecto hepatoprotector de vaccinium floribundum hbk “pushgay” (ericaceae) frente al estrés oxidativo inducido con tetracloruro de carbono Medina R., Carmen Pretel, Orlando Urquiaga, Tito Torres, Patricia Villanueva, Carmen 2015 application/pdf https://dialnet.unirioja.es/servlet/oaiart?codigo=9397856 spa spa https://dialnet.unirioja.es/servlet/oaiart?codigo=9397856 (Revista) ISSN 1994-9073 (Revista) ISSN 1816-0719 LICENCIA DE USO: Los documentos a texto completo incluidos en Dialnet son de acceso libre y propiedad de sus autores y/o editores. Por tanto, cualquier acto de reproducción, distribución, comunicación pública y/o transformación total o parcial requiere el consentimiento expreso y escrito de aquéllos. Cualquier enlace al texto completo de estos documentos deberá hacerse a través de la URL oficial de éstos en Dialnet. Más información: https://dialnet.unirioja.es/info/derechosOAI | INTELLECTUAL PROPERTY RIGHTS STATEMENT: Full text documents hosted by Dialnet are protected by copyright and/or related rights. This digital object is accessible without charge, but its use is subject to the licensing conditions set by its authors or editors. Unless expressly stated otherwise in the licensing conditions, you are free to linking, browsing, printing and making a copy for your own personal purposes. All other acts of reproduction and communication to the public are subject to the licensing conditions expressed by editors and authors and require consent from them. Any link to this document should be made using its official URL in Dialnet. More info: https://dialnet.unirioja.es/info/derechosOAI The Biologist, ISSN 1816-0719, Vol. 13, Nº. 2, 2015 (Ejemplar dedicado a: The Biologist), pags. 235-247 Vaccinium floribundum hepatoprotector tetracloruro de carbono estrés oxidativo hepatoprotective carbon tetrachloride oxidative stress text (article) 2015 ftdialnet 2024-04-03T14:44:14Z The hydroalcoholic extract of the fruit of Vaccinium floribundum HBK "pushgay" was tested in Rattus rattus variety albinus to determine its hepatoprotective effect against oxidative stress induced by carbon tetrachloride. We worked with 20 rats divided into four groups: negative control, which was inoculated for seven days via orogastric tube, sterile physiological saline (SSFE); positive control, which was inoculated two days via orogastric tube, carbon tetrachloride 1 mL·Kg-1 body weight and then by five consecutive days SSFE and experimental, consisting of two groups, which were inoculated, via orogastric tube, carbon tetrachloride 1mL·Kg-1 body weight for two days and then for five consecutive days, the hydroalcoholic extract of Vaccinium floribundum at concentrations of 300 mg·Kg-1 body weight and 600 mg·Kg-1 body weight each group respectively. The concentration of free radicals in liver was determined in all groups by the method of thiobarbituric acid reactive substances; also, histological sections were performed to evaluate the hepatoprotective effect of the hydroalcoholic extract. The average concentrations of free radicals determined in the negative control groups, positivecontrol, and experimental with 300 mg of the hydroalcoholic extract·Kg-1 body weight and 600mg of the hydroalcoholic extract·Kg-1 body weight were, respectively: 6.149; 14.466; 11.794 and 8.786 μg of malondialdehyde.g-1of liver, showing statistically significant differences between the groups (P<0.05). It was determined that the group treated with carbon tetrachloride over thehydroalcoholic extract 600 mg·kg-1 body weight, decreased significantly the amount of free radicals and favored the rapid liver regeneration. El extracto hidroalcohólico del fruto de Vaccinium floribundum HBK “pushgay” fue ensayado en Rattus rattus variedad albinus para determinar su efecto hepatoprotector frente al estrés oxidativo inducido con tetracloruro de carbono. Se trabajó con 20 ratas distribuidas en cuatro grupos: control negativo, al cual se le ... Article in Journal/Newspaper Rattus rattus Dialnet - Portada de revistas (Universidad de La Rioja) |