Gemfibrozilo versus aceite de Sacha Inchi en la reducción de niveles de triglicéridos séricos en Rattus rattus var albinus
Objective: To compare the triglyceride lowering effect of gemfibrozil against that of Sacha Inchi oil in Rattus rattus var albinus. Materials and Methods: Thirty-six animals were used. They were divided in two experimental groups (GE1 and GE2) and a control group (CG). The animals underwent a condit...
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Format: | Article in Journal/Newspaper |
Language: | Spanish |
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Colegio Médico del Perú
2012
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Online Access: | http://dialnet.unirioja.es/servlet/oaiart?codigo=4002826 |
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ftdialnet:oai:dialnet.unirioja.es:ART0000497605 |
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institution |
Open Polar |
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Dialnet - Portada de revistas (Universidad de La Rioja) |
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language |
Spanish |
topic |
Ácidos grasos ácidos grasos Omega-3 gemfibrozilo triglicéridos ratas (DeCS MeSH) Fatty acids fatty acids Omega-3 gemfibrozil triglycerides rats (DeSC |
spellingShingle |
Ácidos grasos ácidos grasos Omega-3 gemfibrozilo triglicéridos ratas (DeCS MeSH) Fatty acids fatty acids Omega-3 gemfibrozil triglycerides rats (DeSC Vicuña Ríos, Augusto Izquierdo Henríquez, Elva Julieta Huamán Saavedra, Juan Jorge Gemfibrozilo versus aceite de Sacha Inchi en la reducción de niveles de triglicéridos séricos en Rattus rattus var albinus |
topic_facet |
Ácidos grasos ácidos grasos Omega-3 gemfibrozilo triglicéridos ratas (DeCS MeSH) Fatty acids fatty acids Omega-3 gemfibrozil triglycerides rats (DeSC |
description |
Objective: To compare the triglyceride lowering effect of gemfibrozil against that of Sacha Inchi oil in Rattus rattus var albinus. Materials and Methods: Thirty-six animals were used. They were divided in two experimental groups (GE1 and GE2) and a control group (CG). The animals underwent a conditioning stage for two weeks, afterwards they were fed with fat-rich meals; and later, the animals from the two experimental groups received Sacha Inchi oil and gemfibrozil, respectively. Serum triglyceride levels were measured at the beginning of the trial, after receiving the fat-rich food and after one and two weeks receiving the test drugs. Results: Serum triglyceride levels had 45,57%, 44,83%, and 27,24% reductions in GE1, GE2 and CG groups, respectively, after two weeks receiving the test drugs. The mean difference of triglyceride values in GE1 and GE2 groups after one and two weeks receiving the test drugs was highly significant compared with values measured after receiving the fat-rich meals; and the difference between the experimental groups and the control group after two weeks using the test drugs was also significant, and the results obtained in the GE1 and GE2 groups were homogeneous (p= 0,600). Conclusion: Sacha Inchi oil showed a triglyceride lowering effect which was similar inefficacy to that of gemfibrozil in Rattus rattus var albinus, after one and two weeks using the test products. Objetivo: Comparar efectos hipotrigliceridemiantes entre gemfibrozilo y aceite de Sacha Inchi en Rattus rattus var albinus. Materiales y Método: Se utilizaron 36 especímenes, los cuales fueron divididos al azar en 2 grupos experimentales (GE1 y GE2) y un grupo control (GC). Fueron sometidos a etapa de acondicionamiento por 2 semanas, luego alimentación rica en grasa por 2 semanas; posteriormente se administró aceite de Sacha Inchi y gemfibrozilo a GE1 y GE2, respectivamente. Se midieron los niveles de triglicéridos séricos en etapa basal, post-alimentación rica en grasa y tratamiento a una y dos semanas. Resultados: ... |
format |
Article in Journal/Newspaper |
author |
Vicuña Ríos, Augusto Izquierdo Henríquez, Elva Julieta Huamán Saavedra, Juan Jorge |
author_facet |
Vicuña Ríos, Augusto Izquierdo Henríquez, Elva Julieta Huamán Saavedra, Juan Jorge |
author_sort |
Vicuña Ríos, Augusto |
title |
Gemfibrozilo versus aceite de Sacha Inchi en la reducción de niveles de triglicéridos séricos en Rattus rattus var albinus |
title_short |
Gemfibrozilo versus aceite de Sacha Inchi en la reducción de niveles de triglicéridos séricos en Rattus rattus var albinus |
title_full |
Gemfibrozilo versus aceite de Sacha Inchi en la reducción de niveles de triglicéridos séricos en Rattus rattus var albinus |
title_fullStr |
Gemfibrozilo versus aceite de Sacha Inchi en la reducción de niveles de triglicéridos séricos en Rattus rattus var albinus |
title_full_unstemmed |
Gemfibrozilo versus aceite de Sacha Inchi en la reducción de niveles de triglicéridos séricos en Rattus rattus var albinus |
title_sort |
gemfibrozilo versus aceite de sacha inchi en la reducción de niveles de triglicéridos séricos en rattus rattus var albinus |
publisher |
Colegio Médico del Perú |
publishDate |
2012 |
url |
http://dialnet.unirioja.es/servlet/oaiart?codigo=4002826 |
long_lat |
ENVELOPE(-63.733,-63.733,-64.983,-64.983) |
geographic |
Azar |
geographic_facet |
Azar |
genre |
Rattus rattus |
genre_facet |
Rattus rattus |
op_source |
Acta Médica Peruana, ISSN 1018-8800, Vol. 29, Nº. 2, 2012, pags. 85-88 |
op_relation |
http://dialnet.unirioja.es/servlet/oaiart?codigo=4002826 (Revista) ISSN 1018-8800 |
op_rights |
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ftdialnet:oai:dialnet.unirioja.es:ART0000497605 2023-05-15T18:04:53+02:00 Gemfibrozilo versus aceite de Sacha Inchi en la reducción de niveles de triglicéridos séricos en Rattus rattus var albinus Vicuña Ríos, Augusto Izquierdo Henríquez, Elva Julieta Huamán Saavedra, Juan Jorge 2012 application/pdf http://dialnet.unirioja.es/servlet/oaiart?codigo=4002826 spa spa Colegio Médico del Perú http://dialnet.unirioja.es/servlet/oaiart?codigo=4002826 (Revista) ISSN 1018-8800 LICENCIA DE USO: Los documentos a texto completo incluidos en Dialnet son de acceso libre y propiedad de sus autores y/o editores. Por tanto, cualquier acto de reproducción, distribución, comunicación pública y/o transformación total o parcial requiere el consentimiento expreso y escrito de aquéllos. Cualquier enlace al texto completo de estos documentos deberá hacerse a través de la URL oficial de éstos en Dialnet. Más información: http://dialnet.unirioja.es/info/derechosOAI | INTELLECTUAL PROPERTY RIGHTS STATEMENT: Full text documents hosted by Dialnet are protected by copyright and/or related rights. This digital object is accessible without charge, but its use is subject to the licensing conditions set by its authors or editors. Unless expressly stated otherwise in the licensing conditions, you are free to linking, browsing, printing and making a copy for your own personal purposes. All other acts of reproduction and communication to the public are subject to the licensing conditions expressed by editors and authors and require consent from them. Any link to this document should be made using its official URL in Dialnet. More info: http://dialnet.unirioja.es/info/derechosOAI Acta Médica Peruana, ISSN 1018-8800, Vol. 29, Nº. 2, 2012, pags. 85-88 Ácidos grasos ácidos grasos Omega-3 gemfibrozilo triglicéridos ratas (DeCS MeSH) Fatty acids fatty acids Omega-3 gemfibrozil triglycerides rats (DeSC text (article) 2012 ftdialnet 2019-08-29T08:07:45Z Objective: To compare the triglyceride lowering effect of gemfibrozil against that of Sacha Inchi oil in Rattus rattus var albinus. Materials and Methods: Thirty-six animals were used. They were divided in two experimental groups (GE1 and GE2) and a control group (CG). The animals underwent a conditioning stage for two weeks, afterwards they were fed with fat-rich meals; and later, the animals from the two experimental groups received Sacha Inchi oil and gemfibrozil, respectively. Serum triglyceride levels were measured at the beginning of the trial, after receiving the fat-rich food and after one and two weeks receiving the test drugs. Results: Serum triglyceride levels had 45,57%, 44,83%, and 27,24% reductions in GE1, GE2 and CG groups, respectively, after two weeks receiving the test drugs. The mean difference of triglyceride values in GE1 and GE2 groups after one and two weeks receiving the test drugs was highly significant compared with values measured after receiving the fat-rich meals; and the difference between the experimental groups and the control group after two weeks using the test drugs was also significant, and the results obtained in the GE1 and GE2 groups were homogeneous (p= 0,600). Conclusion: Sacha Inchi oil showed a triglyceride lowering effect which was similar inefficacy to that of gemfibrozil in Rattus rattus var albinus, after one and two weeks using the test products. Objetivo: Comparar efectos hipotrigliceridemiantes entre gemfibrozilo y aceite de Sacha Inchi en Rattus rattus var albinus. Materiales y Método: Se utilizaron 36 especímenes, los cuales fueron divididos al azar en 2 grupos experimentales (GE1 y GE2) y un grupo control (GC). Fueron sometidos a etapa de acondicionamiento por 2 semanas, luego alimentación rica en grasa por 2 semanas; posteriormente se administró aceite de Sacha Inchi y gemfibrozilo a GE1 y GE2, respectivamente. Se midieron los niveles de triglicéridos séricos en etapa basal, post-alimentación rica en grasa y tratamiento a una y dos semanas. Resultados: ... Article in Journal/Newspaper Rattus rattus Dialnet - Portada de revistas (Universidad de La Rioja) Azar ENVELOPE(-63.733,-63.733,-64.983,-64.983) |