Consequences of high temperatures and premature mortality on the transcriptome and blood physiology of wild adult sockeye salmon (Oncorhynchus nerka)
Elevated river water temperature in the Fraser River, British Columbia, Canada, has been associated with enhanced mortality of adult sockeye salmon (Oncorhynchus nerka) during their upriver migration to spawning grounds. We undertook a study to assess the effects of elevated water temperatures on th...
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Online Access: | http://hdl.handle.net/10536/DRO/DU:30105098 https://figshare.com/articles/journal_contribution/Consequences_of_high_temperatures_and_premature_mortality_on_the_transcriptome_and_blood_physiology_of_wild_adult_sockeye_salmon_Oncorhynchus_nerka_/20823949 |
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ftdeakinunifig:oai:figshare.com:article/20823949 2023-05-15T15:32:55+02:00 Consequences of high temperatures and premature mortality on the transcriptome and blood physiology of wild adult sockeye salmon (Oncorhynchus nerka) K M Jeffries S G Hinch T Sierocinski Timothy Clark E J Eliason M R Donaldson S Li P Pavlidis K M Miller 2012-07-01T00:00:00Z http://hdl.handle.net/10536/DRO/DU:30105098 https://figshare.com/articles/journal_contribution/Consequences_of_high_temperatures_and_premature_mortality_on_the_transcriptome_and_blood_physiology_of_wild_adult_sockeye_salmon_Oncorhynchus_nerka_/20823949 unknown http://hdl.handle.net/10536/DRO/DU:30105098 https://figshare.com/articles/journal_contribution/Consequences_of_high_temperatures_and_premature_mortality_on_the_transcriptome_and_blood_physiology_of_wild_adult_sockeye_salmon_Oncorhynchus_nerka_/20823949 All Rights Reserved Evolutionary Biology Ecology Ecological genomics Pacific salmon premature mortality spawning migration stress temperature Science & Technology Life Sciences & Biomedicine Environmental Sciences & Ecology HEAT-SHOCK RESPONSE GENE-EXPRESSION FRASER-RIVER SIGNAL-TRANSDUCTION BRITISH-COLUMBIA FINAL MATURATION ATLANTIC SALMON OSMOTIC-STRESS RAINBOW-TROUT Text Journal contribution 2012 ftdeakinunifig 2022-11-17T20:15:34Z Elevated river water temperature in the Fraser River, British Columbia, Canada, has been associated with enhanced mortality of adult sockeye salmon (Oncorhynchus nerka) during their upriver migration to spawning grounds. We undertook a study to assess the effects of elevated water temperatures on the gill transcriptome and blood plasma variables in wild-caught sockeye salmon. Naturally migrating sockeye salmon returning to the Fraser River were collected and held at ecologically relevant temperatures of 14°C and 19°C for seven days, a period representing a significant portion of their upstream migration. After seven days, sockeye salmon held at 19°C stimulated heat shock response genes as well as many genes associated with an immune response when compared with fish held at 14°C. Additionally, fish at 19°C had elevated plasma chloride and lactate, suggestive of a disturbance in osmoregulatory homeostasis and a stress response detectable in the blood plasma. Fish that died prematurely over the course of the holding study were compared with time-matched surviving fish; the former fish were characterized by an upregulation of several transcription factors associated with apoptosis and downregulation of genes involved in immune function and antioxidant activity. Ornithine decarboxylase (ODC1) was the most significantly upregulated gene in dying salmon, which suggests an association with cellular apoptosis. We hypothesize that the observed decrease in plasma ions and increases in plasma cortisol that occur in dying fish may be linked to the increase in ODC1. By highlighting these underlying physiological mechanisms, this study enhances our understanding of the processes involved in premature mortality and temperature stress in Pacific salmon during migration to spawning grounds. Other Non-Article Part of Journal/Newspaper Atlantic salmon DRO - Deakin Research Online Canada Pacific British Columbia ENVELOPE(-125.003,-125.003,54.000,54.000) Sockeye ENVELOPE(-130.143,-130.143,54.160,54.160) Fraser River ENVELOPE(-62.243,-62.243,56.619,56.619) |
institution |
Open Polar |
collection |
DRO - Deakin Research Online |
op_collection_id |
ftdeakinunifig |
language |
unknown |
topic |
Evolutionary Biology Ecology Ecological genomics Pacific salmon premature mortality spawning migration stress temperature Science & Technology Life Sciences & Biomedicine Environmental Sciences & Ecology HEAT-SHOCK RESPONSE GENE-EXPRESSION FRASER-RIVER SIGNAL-TRANSDUCTION BRITISH-COLUMBIA FINAL MATURATION ATLANTIC SALMON OSMOTIC-STRESS RAINBOW-TROUT |
spellingShingle |
Evolutionary Biology Ecology Ecological genomics Pacific salmon premature mortality spawning migration stress temperature Science & Technology Life Sciences & Biomedicine Environmental Sciences & Ecology HEAT-SHOCK RESPONSE GENE-EXPRESSION FRASER-RIVER SIGNAL-TRANSDUCTION BRITISH-COLUMBIA FINAL MATURATION ATLANTIC SALMON OSMOTIC-STRESS RAINBOW-TROUT K M Jeffries S G Hinch T Sierocinski Timothy Clark E J Eliason M R Donaldson S Li P Pavlidis K M Miller Consequences of high temperatures and premature mortality on the transcriptome and blood physiology of wild adult sockeye salmon (Oncorhynchus nerka) |
topic_facet |
Evolutionary Biology Ecology Ecological genomics Pacific salmon premature mortality spawning migration stress temperature Science & Technology Life Sciences & Biomedicine Environmental Sciences & Ecology HEAT-SHOCK RESPONSE GENE-EXPRESSION FRASER-RIVER SIGNAL-TRANSDUCTION BRITISH-COLUMBIA FINAL MATURATION ATLANTIC SALMON OSMOTIC-STRESS RAINBOW-TROUT |
description |
Elevated river water temperature in the Fraser River, British Columbia, Canada, has been associated with enhanced mortality of adult sockeye salmon (Oncorhynchus nerka) during their upriver migration to spawning grounds. We undertook a study to assess the effects of elevated water temperatures on the gill transcriptome and blood plasma variables in wild-caught sockeye salmon. Naturally migrating sockeye salmon returning to the Fraser River were collected and held at ecologically relevant temperatures of 14°C and 19°C for seven days, a period representing a significant portion of their upstream migration. After seven days, sockeye salmon held at 19°C stimulated heat shock response genes as well as many genes associated with an immune response when compared with fish held at 14°C. Additionally, fish at 19°C had elevated plasma chloride and lactate, suggestive of a disturbance in osmoregulatory homeostasis and a stress response detectable in the blood plasma. Fish that died prematurely over the course of the holding study were compared with time-matched surviving fish; the former fish were characterized by an upregulation of several transcription factors associated with apoptosis and downregulation of genes involved in immune function and antioxidant activity. Ornithine decarboxylase (ODC1) was the most significantly upregulated gene in dying salmon, which suggests an association with cellular apoptosis. We hypothesize that the observed decrease in plasma ions and increases in plasma cortisol that occur in dying fish may be linked to the increase in ODC1. By highlighting these underlying physiological mechanisms, this study enhances our understanding of the processes involved in premature mortality and temperature stress in Pacific salmon during migration to spawning grounds. |
format |
Other Non-Article Part of Journal/Newspaper |
author |
K M Jeffries S G Hinch T Sierocinski Timothy Clark E J Eliason M R Donaldson S Li P Pavlidis K M Miller |
author_facet |
K M Jeffries S G Hinch T Sierocinski Timothy Clark E J Eliason M R Donaldson S Li P Pavlidis K M Miller |
author_sort |
K M Jeffries |
title |
Consequences of high temperatures and premature mortality on the transcriptome and blood physiology of wild adult sockeye salmon (Oncorhynchus nerka) |
title_short |
Consequences of high temperatures and premature mortality on the transcriptome and blood physiology of wild adult sockeye salmon (Oncorhynchus nerka) |
title_full |
Consequences of high temperatures and premature mortality on the transcriptome and blood physiology of wild adult sockeye salmon (Oncorhynchus nerka) |
title_fullStr |
Consequences of high temperatures and premature mortality on the transcriptome and blood physiology of wild adult sockeye salmon (Oncorhynchus nerka) |
title_full_unstemmed |
Consequences of high temperatures and premature mortality on the transcriptome and blood physiology of wild adult sockeye salmon (Oncorhynchus nerka) |
title_sort |
consequences of high temperatures and premature mortality on the transcriptome and blood physiology of wild adult sockeye salmon (oncorhynchus nerka) |
publishDate |
2012 |
url |
http://hdl.handle.net/10536/DRO/DU:30105098 https://figshare.com/articles/journal_contribution/Consequences_of_high_temperatures_and_premature_mortality_on_the_transcriptome_and_blood_physiology_of_wild_adult_sockeye_salmon_Oncorhynchus_nerka_/20823949 |
long_lat |
ENVELOPE(-125.003,-125.003,54.000,54.000) ENVELOPE(-130.143,-130.143,54.160,54.160) ENVELOPE(-62.243,-62.243,56.619,56.619) |
geographic |
Canada Pacific British Columbia Sockeye Fraser River |
geographic_facet |
Canada Pacific British Columbia Sockeye Fraser River |
genre |
Atlantic salmon |
genre_facet |
Atlantic salmon |
op_relation |
http://hdl.handle.net/10536/DRO/DU:30105098 https://figshare.com/articles/journal_contribution/Consequences_of_high_temperatures_and_premature_mortality_on_the_transcriptome_and_blood_physiology_of_wild_adult_sockeye_salmon_Oncorhynchus_nerka_/20823949 |
op_rights |
All Rights Reserved |
_version_ |
1766363390465277952 |