Epidemiology of Group A rotavirus in rodents and shrews in Bangladesh

AbstractRodents and shrews live in close proximity to humans and have been identified as important hosts of zoonotic pathogens. This study aimed to detect Group A rotavirus (RVA) and its potential risk factors in rodents and shrews in Bangladesh. We captured 417 small mammals from 10 districts with...

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Bibliographic Details
Main Authors: A Islam, ME Hossain, S Islam, MK Rahman, R Hasan, M Miah, MZ Rahman
Format: Article in Journal/Newspaper
Language:unknown
Published: 2022
Subjects:
Veterinary sciences not elsewhere classified
Science & Technology
Life Sciences & Biomedicine
Veterinary Sciences
Prevalence
Bandicota
Mus musculus
Rattus rattus
Suncus murinus
Rotavirus
MICE MUS-DOMESTICUS
MYCOPLASMA-PULMONIS
SUNCUS-MURINUS
KUALA-LUMPUR
WILD RATS
IDENTIFICATION
INFECTION
HELMINTHS
VIRUSES
3009 Veterinary sciences
Online Access:http://hdl.handle.net/10536/DRO/DU:30166676
https://figshare.com/articles/journal_contribution/Epidemiology_of_Group_A_rotavirus_in_rodents_and_shrews_in_Bangladesh/20608065
Description
Summary:AbstractRodents and shrews live in close proximity to humans and have been identified as important hosts of zoonotic pathogens. This study aimed to detect Group A rotavirus (RVA) and its potential risk factors in rodents and shrews in Bangladesh. We captured 417 small mammals from 10 districts with a high degree of contact between people and domestic animals and collected rectal swab samples between June 2011 and October 2013. We tested the swab samples for RVA RNA, targeting the NSP3 gene segment using real-time reverse transcription-polymerase chain reaction (rRT-PCR). Overall, RVA prevalence was the same (6.7%) in both rodents and shrews. We detected RVA RNA in 5.3% of Bandicota bengalensis (4/76; 95% CI: 1.4–12.9), 5.1% of B. indica (4/79; 95% CI: 1.4–12.4), 18.2% of Mus musculus (4/22; 95% CI: 5.2–40.3), 6.7% of Rattus rattus (6/90; 95% CI: 2.5–13.9), and 6.7% of Suncus murinus (10/150; 95% CI: 3.2–11.9). We found significantly more RVA in males (10.4%; OR: 3.4; P = 0.007), animals with a poor body condition score (13.9%; OR: 2.7; P = 0.05), during wet season (8.3%; OR: 4.1; P = 0.032), and in urban land gradients (10.04%; OR: 2.9; P = 0.056). These findings form a basis for understanding the prevalence of rotaviruses circulating among rodents and shrews in this region. We recommend additional molecular studies to ascertain the genotype and zoonotic potential of RVA circulating in rodents and shrews in Bangladesh.

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