Comparing associations of handgrip strength and chair stand performance with all-cause mortality—implications for defining probable sarcopenia: the Tromsø Study 2015–2020 ...

• Main Authors: Johansson, Jonas, Grimsgaard, Sameline, Strand, Bjørn Heine, Sayer, Avan A., Cooper, Rachel
• Format: Article in Journal/Newspaper
• Language: unknown
• Published: figshare 2023
• Subjects: Medicine; Genetics; FOS Biological sciences; Sociology; FOS Sociology; Biological Sciences not elsewhere classified; Science Policy; Tromsø
• Online Access: https://dx.doi.org/10.6084/m9.figshare.c.6938633.v1; https://springernature.figshare.com/collections/Comparing_associations_of_handgrip_strength_and_chair_stand_performance_with_all-cause_mortality_implications_for_defining_probable_sarcopenia_the_Troms_Study_2015_2020/6938633/1

Abstract Background Widely adopted criteria suggest using either low handgrip strength or poor chair stand performance to identify probable sarcopenia. However, there are limited direct comparisons of these measures in relation to important clinical endpoints. We aimed to compare associations between these two measures of probable sarcopenia and all-cause mortality. Methods Analyses included 7838 community-dwelling participants (55% women) aged 40–84 years from the seventh survey of the Tromsø Study (2015–2016), with handgrip strength assessed using a Jamar + Digital Dynamometer and a five-repetition chair stand test (5-CST) also undertaken. We generated sex-specific T-scores and categorised these as “not low”, “low”, and “very low” handgrip strength or 5-CST performance. Cox Proportional Hazard regression models were used to investigate associations between these two categorised performance scores and time to death (up to November 2020 ascertained from the Norwegian Cause of Death registry), adjusted for ...