Genomic regions and signaling pathways associated with indicator traits for feed efficiency in juvenile Atlantic salmon (Salmo salar) ...

• Main Authors: Dvergedal, Hanne, Harvey, Thomas Nelson, Jin, Yang, Ødegård, Jørgen, Grønvold, Lars, Sandve, Simen Rød, Våge, Dag Inge, Moen, Thomas, Klemetsdal, Gunnar
• Format: Article in Journal/Newspaper
• Language: unknown
• Published: figshare 2020
• Subjects: Genetics; FOS Biological sciences; Atlantic salmon; Salmo salar
• Online Access: https://dx.doi.org/10.6084/m9.figshare.c.5199817; https://springernature.figshare.com/collections/Genomic_regions_and_signaling_pathways_associated_with_indicator_traits_for_feed_efficiency_in_juvenile_Atlantic_salmon_Salmo_salar_/5199817

Abstract Background One objective of this study was to identify putative quantitative trait loci (QTL) that affect indicator phenotypes for growth, nitrogen, and carbon metabolism in muscle, liver, and adipose tissue, and for feed efficiency. Another objective was to perform an RNAseq analysis (184 fish from all families), to identify genes that are associated with carbon and nitrogen metabolism in the liver. The material consisted of a family experiment that was performed in freshwater and included 2281 individuals from 23 full-sib families. During the 12-day feed conversion test, families were randomly allocated to family tanks (50 fish per tank and 2 tanks per family) and fed a fishmeal-based diet labeled with the stable isotopes 15N and 13C at inclusion levels of 2 and 1%, respectively. Results Using a linear mixed-model algorithm, a QTL for pre-smolt growth was identified on chromosome 9 and a QTL for carbon metabolism in the liver was identified on chromosome 12 that was closely related to feed ...