Genome-wide association analysis of nutrient traits in the oyster Crassostrea gigas: genetic effect and interaction network ...
Abstract Background Oyster is rich in glycogen and free amino acids and is called â the milk of seaâ . To understand the main genetic effects of these traits and the genetic networks underlying their correlation, we have conducted the whole genome resequencing with 427 oysters collected from the wor...
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ftdatacite:10.6084/m9.figshare.c.4603073 2024-04-28T08:16:36+00:00 Genome-wide association analysis of nutrient traits in the oyster Crassostrea gigas: genetic effect and interaction network ... Meng, Jie Song, Kai Li, Chunyan Liu, Sheng Shi, Ruihui Li, Busu Wang, Ting Li, Ao Que, Huayong Li, Li Zhang, Guofan 2019 https://dx.doi.org/10.6084/m9.figshare.c.4603073 https://springernature.figshare.com/collections/Genome-wide_association_analysis_of_nutrient_traits_in_the_oyster_Crassostrea_gigas_genetic_effect_and_interaction_network/4603073 unknown figshare Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 Genetics FOS Biological sciences Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Virology Collection article 2019 ftdatacite https://doi.org/10.6084/m9.figshare.c.4603073 2024-04-02T11:58:15Z Abstract Background Oyster is rich in glycogen and free amino acids and is called â the milk of seaâ . To understand the main genetic effects of these traits and the genetic networks underlying their correlation, we have conducted the whole genome resequencing with 427 oysters collected from the world-wide scale. Results After association analysis, 168 clustered significant single nucleotide polymorphism (SNP) loci were identified for glycogen content and 17 SNPs were verified with 288 oyster individuals in another wide populations. These were the most important candidate loci for oyster breeding. Among 24 genes in the 100-kb regions of the leading SNP loci, cytochrome P450 17A1 (CYP17A1) contained a non-synonymous SNP and displayed higher expressions in high glycogen content individuals. This might enhance the gluconeogenesis process by the transcriptionally regulating the expression of phosphoenolpyruvate carboxykinase (PEPCK) and glucose 6-phosphatase (G6Pase). Also, for amino acids content, 417 clustered ... Article in Journal/Newspaper Crassostrea gigas DataCite Metadata Store (German National Library of Science and Technology) |
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DataCite Metadata Store (German National Library of Science and Technology) |
op_collection_id |
ftdatacite |
language |
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topic |
Genetics FOS Biological sciences Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Virology |
spellingShingle |
Genetics FOS Biological sciences Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Virology Meng, Jie Song, Kai Li, Chunyan Liu, Sheng Shi, Ruihui Li, Busu Wang, Ting Li, Ao Que, Huayong Li, Li Zhang, Guofan Genome-wide association analysis of nutrient traits in the oyster Crassostrea gigas: genetic effect and interaction network ... |
topic_facet |
Genetics FOS Biological sciences Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Virology |
description |
Abstract Background Oyster is rich in glycogen and free amino acids and is called â the milk of seaâ . To understand the main genetic effects of these traits and the genetic networks underlying their correlation, we have conducted the whole genome resequencing with 427 oysters collected from the world-wide scale. Results After association analysis, 168 clustered significant single nucleotide polymorphism (SNP) loci were identified for glycogen content and 17 SNPs were verified with 288 oyster individuals in another wide populations. These were the most important candidate loci for oyster breeding. Among 24 genes in the 100-kb regions of the leading SNP loci, cytochrome P450 17A1 (CYP17A1) contained a non-synonymous SNP and displayed higher expressions in high glycogen content individuals. This might enhance the gluconeogenesis process by the transcriptionally regulating the expression of phosphoenolpyruvate carboxykinase (PEPCK) and glucose 6-phosphatase (G6Pase). Also, for amino acids content, 417 clustered ... |
format |
Article in Journal/Newspaper |
author |
Meng, Jie Song, Kai Li, Chunyan Liu, Sheng Shi, Ruihui Li, Busu Wang, Ting Li, Ao Que, Huayong Li, Li Zhang, Guofan |
author_facet |
Meng, Jie Song, Kai Li, Chunyan Liu, Sheng Shi, Ruihui Li, Busu Wang, Ting Li, Ao Que, Huayong Li, Li Zhang, Guofan |
author_sort |
Meng, Jie |
title |
Genome-wide association analysis of nutrient traits in the oyster Crassostrea gigas: genetic effect and interaction network ... |
title_short |
Genome-wide association analysis of nutrient traits in the oyster Crassostrea gigas: genetic effect and interaction network ... |
title_full |
Genome-wide association analysis of nutrient traits in the oyster Crassostrea gigas: genetic effect and interaction network ... |
title_fullStr |
Genome-wide association analysis of nutrient traits in the oyster Crassostrea gigas: genetic effect and interaction network ... |
title_full_unstemmed |
Genome-wide association analysis of nutrient traits in the oyster Crassostrea gigas: genetic effect and interaction network ... |
title_sort |
genome-wide association analysis of nutrient traits in the oyster crassostrea gigas: genetic effect and interaction network ... |
publisher |
figshare |
publishDate |
2019 |
url |
https://dx.doi.org/10.6084/m9.figshare.c.4603073 https://springernature.figshare.com/collections/Genome-wide_association_analysis_of_nutrient_traits_in_the_oyster_Crassostrea_gigas_genetic_effect_and_interaction_network/4603073 |
genre |
Crassostrea gigas |
genre_facet |
Crassostrea gigas |
op_rights |
Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 |
op_doi |
https://doi.org/10.6084/m9.figshare.c.4603073 |
_version_ |
1797581666165719040 |