Developmental characteristics of pearl oyster Pinctada fucata martensii: insight into key molecular events related to shell formation, settlement and metamorphosis ...

• Main Authors: Zheng, Zhe, Hao, Ruijuan, Xiong, Xinwei, Jiao, Yu, Deng, Yuewen, Du, Xiaodong
• Format: Article in Journal/Newspaper
• Language: unknown
• Published: figshare 2019
• Subjects: Biochemistry; Cell Biology; Genetics; FOS Biological sciences; Molecular Biology; Environmental Sciences not elsewhere classified; Chemical Sciences not elsewhere classified; Sociology; FOS Sociology; Developmental Biology; Marine Biology; Cancer; Inorganic Chemistry; FOS Chemical sciences; Computational Biology; Crassostrea gigas; Pacific oyster
• Online Access: https://dx.doi.org/10.6084/m9.figshare.c.4395473; https://springernature.figshare.com/collections/Developmental_characteristics_of_pearl_oyster_Pinctada_fucata_martensii_insight_into_key_molecular_events_related_to_shell_formation_settlement_and_metamorphosis/4395473

Abstract Background Marine bivalves undergo complex development processes, such as shell morphology conversion and changes of anatomy and life habits. In this study, the transcriptomes of pearl oyster Pinctada fucata martensii and Pacific oyster Crassostrea gigas at different development stages were analyzed to determine the key molecular events related to shell formation, settlement and metamorphosis. Result According to the shell matrix proteome, biomineralization-related genes exhibited a consensus expression model with the critical stages of shell formation. Differential expression analysis of P. f. martensii, revealed the negative regulation and feedback of extracellular matrixs as well as growth factor pathways involved in shell formation of larvae, similar to that in C. gigas. Furthermore, neuroendocrine pathways in hormone receptors, neurotransmitters and neuropeptide receptors were involved in shell formation, settlement and metamorphosis. Conclusion Our research demonstrated the main clusters of ...