Patterns of homozygosity in insular and continental goat breeds

Abstract Background Genetic isolation of breeds may result in a significant loss of diversity and have consequences on health and performance. In this study, we examined the effect of geographic isolation on caprine genetic diversity patterns by genotyping 480 individuals from 25 European and Africa...

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Bibliographic Details
Main Authors: Cardoso, Taina, Amills, Marcel, Bertolini, Francesca, Rothschild, Max, Marras, Gabriele, Boink, Geert, Jordana, Jordi, Capote, Juan, Carolan, Sean, JĂłn Hallsson, Kantanen, Juha, Agueda Pons, Lenstra, Johannes
Format: Article in Journal/Newspaper
Language:unknown
Published: Figshare 2018
Subjects:
Genetics
FOS Biological sciences
Biotechnology
Evolutionary Biology
Ecology
69999 Biological Sciences not elsewhere classified
Science Policy
Iceland
Online Access:https://dx.doi.org/10.6084/m9.figshare.c.4305845
https://figshare.com/collections/Patterns_of_homozygosity_in_insular_and_continental_goat_breeds/4305845
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Summary:Abstract Background Genetic isolation of breeds may result in a significant loss of diversity and have consequences on health and performance. In this study, we examined the effect of geographic isolation on caprine genetic diversity patterns by genotyping 480 individuals from 25 European and African breeds with the Goat SNP50 BeadChip and comparing patterns of homozygosity of insular and nearby continental breeds. Results Among the breeds analysed, number and total length of ROH varied considerably and depending on breeds, ROH could cover a substantial fraction of the genome (up to 1.6Â Gb in Icelandic goats). When compared with their continental counterparts, goats from Iceland, Madagascar, La Palma and Ireland (Bilberry and Arran) displayed a significant increase in ROH coverage, ROH number and FROH values (P value

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