Evolution in chronic cold: varied loss of cellular response to heat in Antarctic notothenioid fish
Abstract Background Confined within the freezing Southern Ocean, the Antarctic notothenioids have evolved to become both cold adapted and cold specialized. A marked signature of cold specialization is an apparent loss of the cellular heat shock response (HSR). As the HSR has been examined in very fe...
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ftdatacite:10.6084/m9.figshare.c.4238360.v1 2023-05-15T13:48:16+02:00 Evolution in chronic cold: varied loss of cellular response to heat in Antarctic notothenioid fish Bilyk, Kevin Vargas-Chacoff, Luis C.-H.Christina Cheng 2018 https://dx.doi.org/10.6084/m9.figshare.c.4238360.v1 https://figshare.com/collections/Evolution_in_chronic_cold_varied_loss_of_cellular_response_to_heat_in_Antarctic_notothenioid_fish/4238360/1 unknown Figshare https://dx.doi.org/10.1186/s12862-018-1254-6 https://dx.doi.org/10.6084/m9.figshare.c.4238360 CC BY 4.0 https://creativecommons.org/licenses/by/4.0 CC-BY Cell Biology Genetics FOS Biological sciences Molecular Biology Physiology Biotechnology Evolutionary Biology 59999 Environmental Sciences not elsewhere classified FOS Earth and related environmental sciences Ecology Marine Biology Inorganic Chemistry FOS Chemical sciences 111714 Mental Health FOS Health sciences 110309 Infectious Diseases Plant Biology Computational Biology Collection article 2018 ftdatacite https://doi.org/10.6084/m9.figshare.c.4238360.v1 https://doi.org/10.1186/s12862-018-1254-6 https://doi.org/10.6084/m9.figshare.c.4238360 2021-11-05T12:55:41Z Abstract Background Confined within the freezing Southern Ocean, the Antarctic notothenioids have evolved to become both cold adapted and cold specialized. A marked signature of cold specialization is an apparent loss of the cellular heat shock response (HSR). As the HSR has been examined in very few notothenioid species to-date, it remains unknown whether HSR loss pervades the Antarctic radiation, or whether the broader cellular responses to heat stress has sustained similar loss. Understanding the evolutionary status of these responses in this stenothermal taxon is crucial for evaluating its adaptive potential to ocean warming under climate change. Results In this study, we used an acute heat stress protocol followed by RNA-Seq analyses to study the evolution of cellular-wide transcriptional responses to heat stress across three select notothenioid lineages - the basal temperate and nearest non-Antarctic sister species Eleginops maclovinus serving as ancestral proxy, the cryopelagic Pagothenia borchgrevinki and the icefish Chionodraco rastrospinosus representing cold-adapted red-blooded and hemoglobinless Antarctic notothenioids respectively. E. maclovinus displayed robust cellular stress responses including the ER Unfolded Protein Response and the cytosolic HSR, cementing the HSR as a plesiomorphy that preceded Antarctic notothenioid radiation. While the transcriptional response to heat stress was minimal in P. borchgrevinki, C. rastrospinosus exhibited robust responses in the broader cellular networks especially in inflammatory responses despite lacking the classic HSR and UPR. Conclusion The disparate patterns observed in these two archetypal Antarctic species indicate the evolutionary status in cellular ability to mitigate acute heat stress varies even among Antarctic lineages, which may affect their adaptive potential in coping with a warming world. Article in Journal/Newspaper Antarc* Antarctic Icefish Southern Ocean DataCite Metadata Store (German National Library of Science and Technology) Antarctic Southern Ocean The Antarctic |
institution |
Open Polar |
collection |
DataCite Metadata Store (German National Library of Science and Technology) |
op_collection_id |
ftdatacite |
language |
unknown |
topic |
Cell Biology Genetics FOS Biological sciences Molecular Biology Physiology Biotechnology Evolutionary Biology 59999 Environmental Sciences not elsewhere classified FOS Earth and related environmental sciences Ecology Marine Biology Inorganic Chemistry FOS Chemical sciences 111714 Mental Health FOS Health sciences 110309 Infectious Diseases Plant Biology Computational Biology |
spellingShingle |
Cell Biology Genetics FOS Biological sciences Molecular Biology Physiology Biotechnology Evolutionary Biology 59999 Environmental Sciences not elsewhere classified FOS Earth and related environmental sciences Ecology Marine Biology Inorganic Chemistry FOS Chemical sciences 111714 Mental Health FOS Health sciences 110309 Infectious Diseases Plant Biology Computational Biology Bilyk, Kevin Vargas-Chacoff, Luis C.-H.Christina Cheng Evolution in chronic cold: varied loss of cellular response to heat in Antarctic notothenioid fish |
topic_facet |
Cell Biology Genetics FOS Biological sciences Molecular Biology Physiology Biotechnology Evolutionary Biology 59999 Environmental Sciences not elsewhere classified FOS Earth and related environmental sciences Ecology Marine Biology Inorganic Chemistry FOS Chemical sciences 111714 Mental Health FOS Health sciences 110309 Infectious Diseases Plant Biology Computational Biology |
description |
Abstract Background Confined within the freezing Southern Ocean, the Antarctic notothenioids have evolved to become both cold adapted and cold specialized. A marked signature of cold specialization is an apparent loss of the cellular heat shock response (HSR). As the HSR has been examined in very few notothenioid species to-date, it remains unknown whether HSR loss pervades the Antarctic radiation, or whether the broader cellular responses to heat stress has sustained similar loss. Understanding the evolutionary status of these responses in this stenothermal taxon is crucial for evaluating its adaptive potential to ocean warming under climate change. Results In this study, we used an acute heat stress protocol followed by RNA-Seq analyses to study the evolution of cellular-wide transcriptional responses to heat stress across three select notothenioid lineages - the basal temperate and nearest non-Antarctic sister species Eleginops maclovinus serving as ancestral proxy, the cryopelagic Pagothenia borchgrevinki and the icefish Chionodraco rastrospinosus representing cold-adapted red-blooded and hemoglobinless Antarctic notothenioids respectively. E. maclovinus displayed robust cellular stress responses including the ER Unfolded Protein Response and the cytosolic HSR, cementing the HSR as a plesiomorphy that preceded Antarctic notothenioid radiation. While the transcriptional response to heat stress was minimal in P. borchgrevinki, C. rastrospinosus exhibited robust responses in the broader cellular networks especially in inflammatory responses despite lacking the classic HSR and UPR. Conclusion The disparate patterns observed in these two archetypal Antarctic species indicate the evolutionary status in cellular ability to mitigate acute heat stress varies even among Antarctic lineages, which may affect their adaptive potential in coping with a warming world. |
format |
Article in Journal/Newspaper |
author |
Bilyk, Kevin Vargas-Chacoff, Luis C.-H.Christina Cheng |
author_facet |
Bilyk, Kevin Vargas-Chacoff, Luis C.-H.Christina Cheng |
author_sort |
Bilyk, Kevin |
title |
Evolution in chronic cold: varied loss of cellular response to heat in Antarctic notothenioid fish |
title_short |
Evolution in chronic cold: varied loss of cellular response to heat in Antarctic notothenioid fish |
title_full |
Evolution in chronic cold: varied loss of cellular response to heat in Antarctic notothenioid fish |
title_fullStr |
Evolution in chronic cold: varied loss of cellular response to heat in Antarctic notothenioid fish |
title_full_unstemmed |
Evolution in chronic cold: varied loss of cellular response to heat in Antarctic notothenioid fish |
title_sort |
evolution in chronic cold: varied loss of cellular response to heat in antarctic notothenioid fish |
publisher |
Figshare |
publishDate |
2018 |
url |
https://dx.doi.org/10.6084/m9.figshare.c.4238360.v1 https://figshare.com/collections/Evolution_in_chronic_cold_varied_loss_of_cellular_response_to_heat_in_Antarctic_notothenioid_fish/4238360/1 |
geographic |
Antarctic Southern Ocean The Antarctic |
geographic_facet |
Antarctic Southern Ocean The Antarctic |
genre |
Antarc* Antarctic Icefish Southern Ocean |
genre_facet |
Antarc* Antarctic Icefish Southern Ocean |
op_relation |
https://dx.doi.org/10.1186/s12862-018-1254-6 https://dx.doi.org/10.6084/m9.figshare.c.4238360 |
op_rights |
CC BY 4.0 https://creativecommons.org/licenses/by/4.0 |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.6084/m9.figshare.c.4238360.v1 https://doi.org/10.1186/s12862-018-1254-6 https://doi.org/10.6084/m9.figshare.c.4238360 |
_version_ |
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