Hypothesis and data-driven dietary patterns and colorectal Cancer survival: findings from Newfoundland and Labrador colorectal Cancer cohort ...

• Main Authors: Sharma, Ishor, Roebothan, Barbara, Zhu, Yun, Woodrow, Jennifer, Parfrey, Patrick, Mclaughlin, John, Wang, Peter
• Format: Article in Journal/Newspaper
• Language: unknown
• Published: figshare 2018
• Subjects: Medicine; Biotechnology; Environmental Sciences not elsewhere classified; Biological Sciences not elsewhere classified; Mathematical Sciences not elsewhere classified; Cancer; Science Policy; Newfoundland
• Online Access: https://dx.doi.org/10.6084/m9.figshare.c.4112618.v1; https://springernature.figshare.com/collections/Hypothesis_and_data-driven_dietary_patterns_and_colorectal_Cancer_survival_findings_from_Newfoundland_and_Labrador_colorectal_Cancer_cohort/4112618/1

Abstract Background Dietary patterns are commonly used in epidemiological research, yet there have been few studies assessing if and how research results may vary across dietary patterns. This study aimed to estimate the risk of mortality/recurrence/metastasis using different dietary patterns and comparison amongst the patterns. Methods Dietary patterns were identified by Cluster Analysis (CA), Principal Component Analysis (PCA), Alternate Mediterranean Diet score (altMED), Recommended Food Score (RFS) and Dietary Inflammatory Index (DII) scores using a 169-item food frequency questionnaire. Five hundred thirty-two colorectal cancer patients diagnosed between 1999 and 2003 in Newfoundland were followed-up until 2010. Overall Mortality (OM) and combined Mortality, Recurrence or Metastasis (cMRM) were identified. Comparisons were made with adjusted Cox proportional Hazards Ratios (HRs), correlation coefficients and the distributions of individuals in defined clusters by quartiles of factor and index scores. ...