Transcriptional development of phospholipid and lipoprotein metabolism in different intestinal regions of Atlantic salmon (Salmo salar) fry ...

Abstract Background It has been suggested that the high phospholipid (PL) requirement in Atlantic salmon (Salmo salar) fry is due to insufficient intestinal de-novo synthesis causing low lipoprotein (LP) production and reduced transport capacity of dietary lipids. However, in-depth ontogenetic analy...

Full description

Bibliographic Details
Main Authors: Jin, Yang, Olsen, Rolf, Østensen, Mari-Ann, Gillard, Gareth, Korsvoll, Sven, Santi, Nina, Gjuvsland, Arne, Vik, Jon, Torgersen, Jacob, Sandve, Simen, Olsen, Yngvar
Format: Article in Journal/Newspaper
Language:unknown
Published: figshare 2018
Subjects:
Biophysics
Medicine
Cell Biology
Genetics
FOS Biological sciences
Molecular Biology
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Developmental Biology
Marine Biology
Inorganic Chemistry
FOS Chemical sciences
Infectious Diseases
FOS Health sciences
Computational Biology
Atlantic salmon
Salmo salar
Online Access:https://dx.doi.org/10.6084/m9.figshare.c.4071434.v1
https://springernature.figshare.com/collections/Transcriptional_development_of_phospholipid_and_lipoprotein_metabolism_in_different_intestinal_regions_of_Atlantic_salmon_Salmo_salar_fry/4071434/1
Description
Summary:Abstract Background It has been suggested that the high phospholipid (PL) requirement in Atlantic salmon (Salmo salar) fry is due to insufficient intestinal de-novo synthesis causing low lipoprotein (LP) production and reduced transport capacity of dietary lipids. However, in-depth ontogenetic analysis of intestinal PL and LP synthesis with the development of salmon has yet to be performed. Therefore, in this paper we used RNA-Seq technology to investigate the expression of genes involved in PL synthesis and LP formation throughout early developmental stages and associate insufficient expression of synthesis pathways in salmon fry with its higher dietary PL requirement. There was a special focus on the understanding homologous genes, especially those from salmonid-specific fourth vertebrate whole-genome duplication (Ss4R), and their contribution to salmonid specific features of regulation of PL metabolic pathways. Salmon fry were sampled at 0.16 g (1 day before first-feeding), 2.5 and 10 g stages of ...

Similar Items