Early life swimming pool exposure and asthma onset in children – a case-control study
Abstract Background Trichloramine exposure in indoor swimming pools has been suggested to cause asthma in children. We aimed to investigate the risk of asthma onset among children in relation to individual trichloramine exposure. Methods A longitudinal nested case-control study of 337 children with...
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ftdatacite:10.6084/m9.figshare.c.4067153.v1 2023-05-15T17:44:53+02:00 Early life swimming pool exposure and asthma onset in children – a case-control study Andersson, Martin Backman, Helena Nordberg, Gunnar Hagenbjörk, Annika Hedman, Linnea Eriksson, Kåre Forsberg, Bertil Rönmark, Eva 2018 https://dx.doi.org/10.6084/m9.figshare.c.4067153.v1 https://figshare.com/collections/Early_life_swimming_pool_exposure_and_asthma_onset_in_children_a_case-control_study/4067153/1 unknown Figshare https://dx.doi.org/10.1186/s12940-018-0383-0 https://dx.doi.org/10.6084/m9.figshare.c.4067153 CC BY 4.0 https://creativecommons.org/licenses/by/4.0 CC-BY Medicine Genetics FOS Biological sciences 59999 Environmental Sciences not elsewhere classified FOS Earth and related environmental sciences Immunology FOS Clinical medicine 69999 Biological Sciences not elsewhere classified Science Policy 110309 Infectious Diseases FOS Health sciences Collection article 2018 ftdatacite https://doi.org/10.6084/m9.figshare.c.4067153.v1 https://doi.org/10.1186/s12940-018-0383-0 https://doi.org/10.6084/m9.figshare.c.4067153 2021-11-05T12:55:41Z Abstract Background Trichloramine exposure in indoor swimming pools has been suggested to cause asthma in children. We aimed to investigate the risk of asthma onset among children in relation to individual trichloramine exposure. Methods A longitudinal nested case-control study of 337 children with asthma (cases) and 633 controls aged 16–17 years was performed within a population-based cohort from The Obstructive Lung Disease in Northern Sweden studies (OLIN). Year of asthma onset and exposure time at different ages were obtained in telephone interviews. Trichloramine concentrations in the pool buildings were measured. Skin prick test results for inhalant allergens were available from previous examinations of the cohort. The risk for asthma was analyzed in relation to the cumulative trichloramine exposure before onset of asthma. Results The participation rate was high in the original cohort (88 to 96%), and in the case-control study (80%). Trichloramine concentrations ranged from 0.020 to 0.55 mg/m3 (mean 0.15 mg/m3). Swimming pool exposure in early life was associated with a significantly higher risk of pre-school asthma onset. A dose-response relationship between swimming pool exposure and asthma was indicated in children with asthma onset at 1 year of age. Children who were both sensitized and exposed had a particularly high risk. Conclusions Early life exposure to chlorinated swimming pool environments was associated with pre-school asthma onset. Article in Journal/Newspaper Northern Sweden DataCite Metadata Store (German National Library of Science and Technology) |
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collection |
DataCite Metadata Store (German National Library of Science and Technology) |
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language |
unknown |
topic |
Medicine Genetics FOS Biological sciences 59999 Environmental Sciences not elsewhere classified FOS Earth and related environmental sciences Immunology FOS Clinical medicine 69999 Biological Sciences not elsewhere classified Science Policy 110309 Infectious Diseases FOS Health sciences |
spellingShingle |
Medicine Genetics FOS Biological sciences 59999 Environmental Sciences not elsewhere classified FOS Earth and related environmental sciences Immunology FOS Clinical medicine 69999 Biological Sciences not elsewhere classified Science Policy 110309 Infectious Diseases FOS Health sciences Andersson, Martin Backman, Helena Nordberg, Gunnar Hagenbjörk, Annika Hedman, Linnea Eriksson, Kåre Forsberg, Bertil Rönmark, Eva Early life swimming pool exposure and asthma onset in children – a case-control study |
topic_facet |
Medicine Genetics FOS Biological sciences 59999 Environmental Sciences not elsewhere classified FOS Earth and related environmental sciences Immunology FOS Clinical medicine 69999 Biological Sciences not elsewhere classified Science Policy 110309 Infectious Diseases FOS Health sciences |
description |
Abstract Background Trichloramine exposure in indoor swimming pools has been suggested to cause asthma in children. We aimed to investigate the risk of asthma onset among children in relation to individual trichloramine exposure. Methods A longitudinal nested case-control study of 337 children with asthma (cases) and 633 controls aged 16–17 years was performed within a population-based cohort from The Obstructive Lung Disease in Northern Sweden studies (OLIN). Year of asthma onset and exposure time at different ages were obtained in telephone interviews. Trichloramine concentrations in the pool buildings were measured. Skin prick test results for inhalant allergens were available from previous examinations of the cohort. The risk for asthma was analyzed in relation to the cumulative trichloramine exposure before onset of asthma. Results The participation rate was high in the original cohort (88 to 96%), and in the case-control study (80%). Trichloramine concentrations ranged from 0.020 to 0.55 mg/m3 (mean 0.15 mg/m3). Swimming pool exposure in early life was associated with a significantly higher risk of pre-school asthma onset. A dose-response relationship between swimming pool exposure and asthma was indicated in children with asthma onset at 1 year of age. Children who were both sensitized and exposed had a particularly high risk. Conclusions Early life exposure to chlorinated swimming pool environments was associated with pre-school asthma onset. |
format |
Article in Journal/Newspaper |
author |
Andersson, Martin Backman, Helena Nordberg, Gunnar Hagenbjörk, Annika Hedman, Linnea Eriksson, Kåre Forsberg, Bertil Rönmark, Eva |
author_facet |
Andersson, Martin Backman, Helena Nordberg, Gunnar Hagenbjörk, Annika Hedman, Linnea Eriksson, Kåre Forsberg, Bertil Rönmark, Eva |
author_sort |
Andersson, Martin |
title |
Early life swimming pool exposure and asthma onset in children – a case-control study |
title_short |
Early life swimming pool exposure and asthma onset in children – a case-control study |
title_full |
Early life swimming pool exposure and asthma onset in children – a case-control study |
title_fullStr |
Early life swimming pool exposure and asthma onset in children – a case-control study |
title_full_unstemmed |
Early life swimming pool exposure and asthma onset in children – a case-control study |
title_sort |
early life swimming pool exposure and asthma onset in children – a case-control study |
publisher |
Figshare |
publishDate |
2018 |
url |
https://dx.doi.org/10.6084/m9.figshare.c.4067153.v1 https://figshare.com/collections/Early_life_swimming_pool_exposure_and_asthma_onset_in_children_a_case-control_study/4067153/1 |
genre |
Northern Sweden |
genre_facet |
Northern Sweden |
op_relation |
https://dx.doi.org/10.1186/s12940-018-0383-0 https://dx.doi.org/10.6084/m9.figshare.c.4067153 |
op_rights |
CC BY 4.0 https://creativecommons.org/licenses/by/4.0 |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.6084/m9.figshare.c.4067153.v1 https://doi.org/10.1186/s12940-018-0383-0 https://doi.org/10.6084/m9.figshare.c.4067153 |
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