Dataset for: Human physiological and metabolic responses to an attempted winter crossing of Antarctica: the effects of prolonged hypobaric hypoxia. ...
An insufficient supply of oxygen to the tissues (hypoxia), as is experienced upon high altitude exposure, elicits physiological acclimatisation mechanisms alongside metabolic remodelling. Details of the integrative adaptive processes in response to chronic hypobaric hypoxic exposure remain to be suf...
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Online Access: | https://dx.doi.org/10.6084/m9.figshare.c.3986340 https://wiley.figshare.com/collections/Dataset_for_Human_physiological_and_metabolic_responses_to_an_attempted_winter_crossing_of_Antarctica_the_effects_of_prolonged_hypobaric_hypoxia_/3986340 |
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ftdatacite:10.6084/m9.figshare.c.3986340 2024-10-13T14:01:31+00:00 Dataset for: Human physiological and metabolic responses to an attempted winter crossing of Antarctica: the effects of prolonged hypobaric hypoxia. ... O'Brien, Katie A Pollock, Ross D Stroud, Mike A Lambert, Rob J Kumar, Alex Atkinson, Robert A Green, David A Anton-Solanas, Ana Edwards, Lindsay M Harridge, Steve D.R. Admin, Wiley 2018 https://dx.doi.org/10.6084/m9.figshare.c.3986340 https://wiley.figshare.com/collections/Dataset_for_Human_physiological_and_metabolic_responses_to_an_attempted_winter_crossing_of_Antarctica_the_effects_of_prolonged_hypobaric_hypoxia_/3986340 unknown Wiley Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 Animal physiology - biophysics Animal physiology - cell Animal physiology - systems Systems biology Collection article 2018 ftdatacite https://doi.org/10.6084/m9.figshare.c.3986340 2024-10-01T12:16:53Z An insufficient supply of oxygen to the tissues (hypoxia), as is experienced upon high altitude exposure, elicits physiological acclimatisation mechanisms alongside metabolic remodelling. Details of the integrative adaptive processes in response to chronic hypobaric hypoxic exposure remain to be sufficiently investigated. In this small applied field study, subjects (n=5, male, age 28-54 yrs) undertook a 40 week Antarctica expedition in the winter months, which included 24 weeks residing above 2500m. Measurements taken pre and post expedition revealed alterations to glucose and fatty acid resonances within the serum metabolic profile, a 7.8 (+ 3.6) % increase in respiratory exchange ratio measured during incremental exercise (area under curve, p>0.01, mean ±SD) and a 2.1(+ 0.8) % decrease in fat tissue (p<0.05) post expedition. This was accompanied by an 11.6 (+1.9) % increase (p>0.001) in VO2 max corrected to % lean mass post expedition. In addition, spine bone mineral density and lung function ... Article in Journal/Newspaper Antarc* Antarctica DataCite |
institution |
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collection |
DataCite |
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ftdatacite |
language |
unknown |
topic |
Animal physiology - biophysics Animal physiology - cell Animal physiology - systems Systems biology |
spellingShingle |
Animal physiology - biophysics Animal physiology - cell Animal physiology - systems Systems biology O'Brien, Katie A Pollock, Ross D Stroud, Mike A Lambert, Rob J Kumar, Alex Atkinson, Robert A Green, David A Anton-Solanas, Ana Edwards, Lindsay M Harridge, Steve D.R. Admin, Wiley Dataset for: Human physiological and metabolic responses to an attempted winter crossing of Antarctica: the effects of prolonged hypobaric hypoxia. ... |
topic_facet |
Animal physiology - biophysics Animal physiology - cell Animal physiology - systems Systems biology |
description |
An insufficient supply of oxygen to the tissues (hypoxia), as is experienced upon high altitude exposure, elicits physiological acclimatisation mechanisms alongside metabolic remodelling. Details of the integrative adaptive processes in response to chronic hypobaric hypoxic exposure remain to be sufficiently investigated. In this small applied field study, subjects (n=5, male, age 28-54 yrs) undertook a 40 week Antarctica expedition in the winter months, which included 24 weeks residing above 2500m. Measurements taken pre and post expedition revealed alterations to glucose and fatty acid resonances within the serum metabolic profile, a 7.8 (+ 3.6) % increase in respiratory exchange ratio measured during incremental exercise (area under curve, p>0.01, mean ±SD) and a 2.1(+ 0.8) % decrease in fat tissue (p<0.05) post expedition. This was accompanied by an 11.6 (+1.9) % increase (p>0.001) in VO2 max corrected to % lean mass post expedition. In addition, spine bone mineral density and lung function ... |
format |
Article in Journal/Newspaper |
author |
O'Brien, Katie A Pollock, Ross D Stroud, Mike A Lambert, Rob J Kumar, Alex Atkinson, Robert A Green, David A Anton-Solanas, Ana Edwards, Lindsay M Harridge, Steve D.R. Admin, Wiley |
author_facet |
O'Brien, Katie A Pollock, Ross D Stroud, Mike A Lambert, Rob J Kumar, Alex Atkinson, Robert A Green, David A Anton-Solanas, Ana Edwards, Lindsay M Harridge, Steve D.R. Admin, Wiley |
author_sort |
O'Brien, Katie A |
title |
Dataset for: Human physiological and metabolic responses to an attempted winter crossing of Antarctica: the effects of prolonged hypobaric hypoxia. ... |
title_short |
Dataset for: Human physiological and metabolic responses to an attempted winter crossing of Antarctica: the effects of prolonged hypobaric hypoxia. ... |
title_full |
Dataset for: Human physiological and metabolic responses to an attempted winter crossing of Antarctica: the effects of prolonged hypobaric hypoxia. ... |
title_fullStr |
Dataset for: Human physiological and metabolic responses to an attempted winter crossing of Antarctica: the effects of prolonged hypobaric hypoxia. ... |
title_full_unstemmed |
Dataset for: Human physiological and metabolic responses to an attempted winter crossing of Antarctica: the effects of prolonged hypobaric hypoxia. ... |
title_sort |
dataset for: human physiological and metabolic responses to an attempted winter crossing of antarctica: the effects of prolonged hypobaric hypoxia. ... |
publisher |
Wiley |
publishDate |
2018 |
url |
https://dx.doi.org/10.6084/m9.figshare.c.3986340 https://wiley.figshare.com/collections/Dataset_for_Human_physiological_and_metabolic_responses_to_an_attempted_winter_crossing_of_Antarctica_the_effects_of_prolonged_hypobaric_hypoxia_/3986340 |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_rights |
Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 |
op_doi |
https://doi.org/10.6084/m9.figshare.c.3986340 |
_version_ |
1812811360657997824 |