Wild eel microbiome reveals that skin mucus of fish could be a natural niche for aquatic mucosal pathogen evolution ...

• Main Authors: Carda-DiĂŠguez, Miguel, Ghai, Rohit, RodrĂ­guez-Valera, Francisco, Amaro, Carmen
• Format: Article in Journal/Newspaper
• Language: unknown
• Published: figshare 2017
• Subjects: Space Science; Microbiology; FOS: Biological sciences; Biotechnology; Evolutionary Biology; Environmental Sciences not elsewhere classified; Chemical Sciences not elsewhere classified; Ecology; Cancer; Inorganic Chemistry; FOS: Chemical sciences; Infectious Diseases; FOS: Health sciences; Anguilla anguilla
• Online Access: https://dx.doi.org/10.6084/m9.figshare.c.3979527.v1; https://springernature.figshare.com/collections/Wild_eel_microbiome_reveals_that_skin_mucus_of_fish_could_be_a_natural_niche_for_aquatic_mucosal_pathogen_evolution/3979527/1

Abstract Background Fish skin mucosal surfaces (SMS) are quite similar in composition and function to some mammalian MS and, in consequence, could constitute an adequate niche for the evolution of mucosal aquatic pathogens in natural environments. We aimed to test this hypothesis by searching for metagenomic and genomic evidences in the SMS-microbiome of a model fish species (Anguilla Anguilla or eel), from different ecosystems (four natural environments of different water salinity and one eel farm) as well as the water microbiome (W-microbiome) surrounding the host. Results Remarkably, potentially pathogenic Vibrio monopolized wild eel SMS-microbiome from natural ecosystems, Vibrio anguillarum/Vibrio vulnificus and Vibrio cholerae/Vibrio metoecus being the most abundant ones in SMS from estuary and lake, respectively. Functions encoded in the SMS-microbiome differed significantly from those in the W-microbiome and allowed us to predict that successful mucus colonizers should have specific genes for (i) ...