Additional file 2: of Prevention of C5aR1 signaling delays microglial inflammatory polarization, favors clearance pathways and suppresses cognitive loss ...

• Main Authors: Hernandez, Michael, Jiang, Shan, Cole, Tracy, Chu, Shu-Hui, Fonseca, Maria, Fang, Melody, Hohsfield, Lindsay, Torres, Maria, Green, Kim, Wetsel, Rick, Mortazavi, Ali, Tenner, Andrea
• Format: Text
• Language: unknown
• Published: Figshare 2017
• Subjects: 29999 Physical Sciences not elsewhere classified; FOS Physical sciences; Medicine; Cell Biology; Neuroscience; Pharmacology; Immunology; FOS Clinical medicine; 69999 Biological Sciences not elsewhere classified; FOS Biological sciences; Arctic
• Online Access: https://dx.doi.org/10.6084/m9.figshare.c.3882769_d2.v1; https://springernature.figshare.com/articles/journal_contribution/Additional_file_2_of_Prevention_of_C5aR1_signaling_delays_microglial_inflammatory_polarization_favors_clearance_pathways_and_suppresses_cognitive_loss/5418118/1

Comparison of IBA1 microglia and Thioflavine S plaque size between Arctic and Arctic/C5aR1KO. (A-D) Representative images of the hippocampus stained for IBA1 and ThioS. (E) Quantification of the number of IBA1+ cells/field of view (FOV) using the spots modules in Bit-plane Imaris 7.5. (F) Quantification of the size of ThioS+ plaques/FOV using the surfaces module in Bit-plane Imaris. Error bars represent SEM, (n = 3–4/group). *p ...