Integrated application of transcriptomics and metabolomics provides insights into glycogen content regulation in the Pacific oyster Crassostrea gigas ...
Abstract Background The Pacific oyster Crassostrea gigas is an important marine fishery resource, which contains high levels of glycogen that contributes to the flavor and the quality of the oyster. However, little is known about the molecular and chemical mechanisms underlying glycogen content diff...
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ftdatacite:10.6084/m9.figshare.c.3877033 2024-04-28T08:16:26+00:00 Integrated application of transcriptomics and metabolomics provides insights into glycogen content regulation in the Pacific oyster Crassostrea gigas ... Li, Busu Song, Kai Meng, Jie Li, Li Zhang, Guofan 2017 https://dx.doi.org/10.6084/m9.figshare.c.3877033 https://springernature.figshare.com/collections/Integrated_application_of_transcriptomics_and_metabolomics_provides_insights_into_glycogen_content_regulation_in_the_Pacific_oyster_Crassostrea_gigas/3877033 unknown figshare Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 Biochemistry Genetics FOS Biological sciences Molecular Biology Ecology Biological Sciences not elsewhere classified Inorganic Chemistry FOS Chemical sciences Computational Biology Collection article 2017 ftdatacite https://doi.org/10.6084/m9.figshare.c.3877033 2024-04-02T11:54:48Z Abstract Background The Pacific oyster Crassostrea gigas is an important marine fishery resource, which contains high levels of glycogen that contributes to the flavor and the quality of the oyster. However, little is known about the molecular and chemical mechanisms underlying glycogen content differences in Pacific oysters. Using a homogeneous cultured Pacific oyster family, we explored these regulatory networks at the level of the metabolome and the transcriptome. Results Oysters with the highest and lowest natural glycogen content were selected for differential transcriptome and metabolome analysis. We identified 1888 differentially-expressed genes, seventy-five differentially-abundant metabolites, which are part of twenty-seven signaling pathways that were enriched using an integrated analysis of the interaction between the differentially-expressed genes and the differentially-abundant metabolites. Based on these results, we found that a high expression of carnitine O-palmitoyltransferase 2 (CPT2), ... Article in Journal/Newspaper Crassostrea gigas Pacific oyster DataCite Metadata Store (German National Library of Science and Technology) |
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collection |
DataCite Metadata Store (German National Library of Science and Technology) |
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topic |
Biochemistry Genetics FOS Biological sciences Molecular Biology Ecology Biological Sciences not elsewhere classified Inorganic Chemistry FOS Chemical sciences Computational Biology |
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Biochemistry Genetics FOS Biological sciences Molecular Biology Ecology Biological Sciences not elsewhere classified Inorganic Chemistry FOS Chemical sciences Computational Biology Li, Busu Song, Kai Meng, Jie Li, Li Zhang, Guofan Integrated application of transcriptomics and metabolomics provides insights into glycogen content regulation in the Pacific oyster Crassostrea gigas ... |
topic_facet |
Biochemistry Genetics FOS Biological sciences Molecular Biology Ecology Biological Sciences not elsewhere classified Inorganic Chemistry FOS Chemical sciences Computational Biology |
description |
Abstract Background The Pacific oyster Crassostrea gigas is an important marine fishery resource, which contains high levels of glycogen that contributes to the flavor and the quality of the oyster. However, little is known about the molecular and chemical mechanisms underlying glycogen content differences in Pacific oysters. Using a homogeneous cultured Pacific oyster family, we explored these regulatory networks at the level of the metabolome and the transcriptome. Results Oysters with the highest and lowest natural glycogen content were selected for differential transcriptome and metabolome analysis. We identified 1888 differentially-expressed genes, seventy-five differentially-abundant metabolites, which are part of twenty-seven signaling pathways that were enriched using an integrated analysis of the interaction between the differentially-expressed genes and the differentially-abundant metabolites. Based on these results, we found that a high expression of carnitine O-palmitoyltransferase 2 (CPT2), ... |
format |
Article in Journal/Newspaper |
author |
Li, Busu Song, Kai Meng, Jie Li, Li Zhang, Guofan |
author_facet |
Li, Busu Song, Kai Meng, Jie Li, Li Zhang, Guofan |
author_sort |
Li, Busu |
title |
Integrated application of transcriptomics and metabolomics provides insights into glycogen content regulation in the Pacific oyster Crassostrea gigas ... |
title_short |
Integrated application of transcriptomics and metabolomics provides insights into glycogen content regulation in the Pacific oyster Crassostrea gigas ... |
title_full |
Integrated application of transcriptomics and metabolomics provides insights into glycogen content regulation in the Pacific oyster Crassostrea gigas ... |
title_fullStr |
Integrated application of transcriptomics and metabolomics provides insights into glycogen content regulation in the Pacific oyster Crassostrea gigas ... |
title_full_unstemmed |
Integrated application of transcriptomics and metabolomics provides insights into glycogen content regulation in the Pacific oyster Crassostrea gigas ... |
title_sort |
integrated application of transcriptomics and metabolomics provides insights into glycogen content regulation in the pacific oyster crassostrea gigas ... |
publisher |
figshare |
publishDate |
2017 |
url |
https://dx.doi.org/10.6084/m9.figshare.c.3877033 https://springernature.figshare.com/collections/Integrated_application_of_transcriptomics_and_metabolomics_provides_insights_into_glycogen_content_regulation_in_the_Pacific_oyster_Crassostrea_gigas/3877033 |
genre |
Crassostrea gigas Pacific oyster |
genre_facet |
Crassostrea gigas Pacific oyster |
op_rights |
Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 |
op_doi |
https://doi.org/10.6084/m9.figshare.c.3877033 |
_version_ |
1797581563357036544 |