Dietary phytochemicals modulate skin gene expression profiles and result in reduced lice counts after experimental infection in Atlantic salmon
Abstract Background The use of phytochemicals is a promising solution in biological control against salmon louse (Lepeophtheirus salmonis). Glucosinolates belong to a diverse group of compounds used as protection against herbivores by plants in the family Brassicaceae, while in vertebrates, ingested...
| Main Authors: | , , , , , |
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| Format: | Article in Journal/Newspaper |
| Language: | unknown |
| Published: |
Figshare
2016
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| Subjects: | |
| Online Access: | https://dx.doi.org/10.6084/m9.figshare.c.3628829 https://figshare.com/collections/Dietary_phytochemicals_modulate_skin_gene_expression_profiles_and_result_in_reduced_lice_counts_after_experimental_infection_in_Atlantic_salmon/3628829 |
| Summary: | Abstract Background The use of phytochemicals is a promising solution in biological control against salmon louse (Lepeophtheirus salmonis). Glucosinolates belong to a diverse group of compounds used as protection against herbivores by plants in the family Brassicaceae, while in vertebrates, ingested glucosinolates exert health-promoting effects due to their antioxidant and detoxifying properties as well as effects on cell proliferation and growth. The aim of this study was to investigate if Atlantic salmon fed two different doses of glucosinolate-enriched feeds would be protected against lice infection. The effects of feeding high dose of glucosinolates before the infection, and of high and low doses five weeks into the infection were studied. Methods Skin was screened by 15 k oligonucleotide microarray and qPCR. Results A 25 % reduction (P |
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