Signatures of natural selection between life cycle stages separated by metamorphosis in European eel
Abstract Background Species showing complex life cycles provide excellent opportunities to study the genetic associations between life cycle stages, as selective pressures may differ before and after metamorphosis. The European eel presents a complex life cycle with two metamorphoses, a first metamo...
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ftdatacite:10.6084/m9.figshare.c.3619766 2023-05-15T16:08:39+02:00 Signatures of natural selection between life cycle stages separated by metamorphosis in European eel J. Pujolar M. Jacobsen D. Bekkevold J. Lobón-Cervià B. Jónsson L. Bernatchez M. Hansen 2015 https://dx.doi.org/10.6084/m9.figshare.c.3619766 https://figshare.com/collections/Signatures_of_natural_selection_between_life_cycle_stages_separated_by_metamorphosis_in_European_eel/3619766 unknown Figshare https://dx.doi.org/10.1186/s12864-015-1754-3 CC BY 4.0 https://creativecommons.org/licenses/by/4.0 CC-BY Genetics FOS Biological sciences Molecular Biology Evolutionary Biology 69999 Biological Sciences not elsewhere classified Developmental Biology Inorganic Chemistry FOS Chemical sciences Collection article 2015 ftdatacite https://doi.org/10.6084/m9.figshare.c.3619766 https://doi.org/10.1186/s12864-015-1754-3 2021-11-05T12:55:41Z Abstract Background Species showing complex life cycles provide excellent opportunities to study the genetic associations between life cycle stages, as selective pressures may differ before and after metamorphosis. The European eel presents a complex life cycle with two metamorphoses, a first metamorphosis from larvae into glass eels (juvenile stage) and a second metamorphosis into silver eels (adult stage). We tested the hypothesis that different genes and gene pathways will be under selection at different life stages when comparing the genetic associations between glass eels and silver eels. Results We used two sets of markers to test for selection: first, we genotyped individuals using a panel of 80 coding-gene single nucleotide polymorphisms (SNPs) developed in American eel; second, we investigated selection at the genome level using a total of 153,423 RAD-sequencing generated SNPs widely distributed across the genome. Using the RAD approach, outlier tests identified a total of 2413 (1.57 %) potentially selected SNPs. Functional annotation analysis identified signal transduction pathways as the most over-represented group of genes, including MAPK/Erk signalling, calcium signalling and GnRH (gonadotropin-releasing hormone) signalling. Many of the over-represented pathways were related to growth, while others could result from the different conditions that eels inhabit during their life cycle. Conclusions The observation of different genes and gene pathways under selection when comparing glass eels vs. silver eels supports the adaptive decoupling hypothesis for the benefits of metamorphosis. Partitioning the life cycle into discrete morphological phases may be overall beneficial since it allows the different life stages to respond independently to their unique selection pressures. This might translate into a more effective use of food and niche resources and/or performance of phase-specific tasks (e.g. feeding in the case of glass eels, migrating and reproducing in the case of silver eels). Article in Journal/Newspaper European eel DataCite Metadata Store (German National Library of Science and Technology) |
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Open Polar |
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DataCite Metadata Store (German National Library of Science and Technology) |
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language |
unknown |
topic |
Genetics FOS Biological sciences Molecular Biology Evolutionary Biology 69999 Biological Sciences not elsewhere classified Developmental Biology Inorganic Chemistry FOS Chemical sciences |
spellingShingle |
Genetics FOS Biological sciences Molecular Biology Evolutionary Biology 69999 Biological Sciences not elsewhere classified Developmental Biology Inorganic Chemistry FOS Chemical sciences J. Pujolar M. Jacobsen D. Bekkevold J. Lobón-Cervià B. Jónsson L. Bernatchez M. Hansen Signatures of natural selection between life cycle stages separated by metamorphosis in European eel |
topic_facet |
Genetics FOS Biological sciences Molecular Biology Evolutionary Biology 69999 Biological Sciences not elsewhere classified Developmental Biology Inorganic Chemistry FOS Chemical sciences |
description |
Abstract Background Species showing complex life cycles provide excellent opportunities to study the genetic associations between life cycle stages, as selective pressures may differ before and after metamorphosis. The European eel presents a complex life cycle with two metamorphoses, a first metamorphosis from larvae into glass eels (juvenile stage) and a second metamorphosis into silver eels (adult stage). We tested the hypothesis that different genes and gene pathways will be under selection at different life stages when comparing the genetic associations between glass eels and silver eels. Results We used two sets of markers to test for selection: first, we genotyped individuals using a panel of 80 coding-gene single nucleotide polymorphisms (SNPs) developed in American eel; second, we investigated selection at the genome level using a total of 153,423 RAD-sequencing generated SNPs widely distributed across the genome. Using the RAD approach, outlier tests identified a total of 2413 (1.57 %) potentially selected SNPs. Functional annotation analysis identified signal transduction pathways as the most over-represented group of genes, including MAPK/Erk signalling, calcium signalling and GnRH (gonadotropin-releasing hormone) signalling. Many of the over-represented pathways were related to growth, while others could result from the different conditions that eels inhabit during their life cycle. Conclusions The observation of different genes and gene pathways under selection when comparing glass eels vs. silver eels supports the adaptive decoupling hypothesis for the benefits of metamorphosis. Partitioning the life cycle into discrete morphological phases may be overall beneficial since it allows the different life stages to respond independently to their unique selection pressures. This might translate into a more effective use of food and niche resources and/or performance of phase-specific tasks (e.g. feeding in the case of glass eels, migrating and reproducing in the case of silver eels). |
format |
Article in Journal/Newspaper |
author |
J. Pujolar M. Jacobsen D. Bekkevold J. Lobón-Cervià B. Jónsson L. Bernatchez M. Hansen |
author_facet |
J. Pujolar M. Jacobsen D. Bekkevold J. Lobón-Cervià B. Jónsson L. Bernatchez M. Hansen |
author_sort |
J. Pujolar |
title |
Signatures of natural selection between life cycle stages separated by metamorphosis in European eel |
title_short |
Signatures of natural selection between life cycle stages separated by metamorphosis in European eel |
title_full |
Signatures of natural selection between life cycle stages separated by metamorphosis in European eel |
title_fullStr |
Signatures of natural selection between life cycle stages separated by metamorphosis in European eel |
title_full_unstemmed |
Signatures of natural selection between life cycle stages separated by metamorphosis in European eel |
title_sort |
signatures of natural selection between life cycle stages separated by metamorphosis in european eel |
publisher |
Figshare |
publishDate |
2015 |
url |
https://dx.doi.org/10.6084/m9.figshare.c.3619766 https://figshare.com/collections/Signatures_of_natural_selection_between_life_cycle_stages_separated_by_metamorphosis_in_European_eel/3619766 |
genre |
European eel |
genre_facet |
European eel |
op_relation |
https://dx.doi.org/10.1186/s12864-015-1754-3 |
op_rights |
CC BY 4.0 https://creativecommons.org/licenses/by/4.0 |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.6084/m9.figshare.c.3619766 https://doi.org/10.1186/s12864-015-1754-3 |
_version_ |
1766404678002671616 |