The comprehensive immunomodulation of NeurimmiRs in haemocytes of oyster Crassostrea gigas after acetylcholine and norepinephrine stimulation ...
Abstract Background Neural-endocrine-immune (NEI) system is a major modulation network among the nervous, endocrine and immune system and weights greatly in maintaining homeostasis of organisms during stress and infection. Some microRNAs are found interacting with NEI system (designated NeurimmiRs),...
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ftdatacite:10.6084/m9.figshare.c.3605885 2024-04-28T08:16:25+00:00 The comprehensive immunomodulation of NeurimmiRs in haemocytes of oyster Crassostrea gigas after acetylcholine and norepinephrine stimulation ... Chen, Hao Wang, Lingling Zhou, Zhi Hou, Zhanhui Liu, Zhaoqun Wang, Weilin Gao, Dahai Gao, Qiang Wang, Mengqiang Song, Linsheng 2015 https://dx.doi.org/10.6084/m9.figshare.c.3605885 https://springernature.figshare.com/collections/The_comprehensive_immunomodulation_of_NeurimmiRs_in_haemocytes_of_oyster_Crassostrea_gigas_after_acetylcholine_and_norepinephrine_stimulation/3605885 unknown figshare Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 Medicine Genetics FOS Biological sciences Molecular Biology Physiology Immunology FOS Clinical medicine Biological Sciences not elsewhere classified Science Policy Collection article 2015 ftdatacite https://doi.org/10.6084/m9.figshare.c.3605885 2024-04-02T11:53:17Z Abstract Background Neural-endocrine-immune (NEI) system is a major modulation network among the nervous, endocrine and immune system and weights greatly in maintaining homeostasis of organisms during stress and infection. Some microRNAs are found interacting with NEI system (designated NeurimmiRs), addressing swift modulations on immune system. The oyster Crassostrea gigas, as an intertidal bivalve, has evolved a primary NEI system. However, the knowledge about NeurimmiRs in oysters remains largely unknown. Results Six small RNA libraries from haemocytes of oysters stimulated with acetylcholine (ACh) and norepinephrine (NE) were sequenced to identify neurotransmitter-responsive miRNAs and survey their immunomodulation roles. A total of 331 miRNAs (132 identified in the present study plus 199 identified previously) were subjected to expression analysis, and twenty-one and sixteen of them were found ACh- or NE-responsive, respectively (FDR < 0.05). Meanwhile, 21 miRNAs exhibited different expression ... Article in Journal/Newspaper Crassostrea gigas DataCite Metadata Store (German National Library of Science and Technology) |
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collection |
DataCite Metadata Store (German National Library of Science and Technology) |
op_collection_id |
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unknown |
topic |
Medicine Genetics FOS Biological sciences Molecular Biology Physiology Immunology FOS Clinical medicine Biological Sciences not elsewhere classified Science Policy |
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Medicine Genetics FOS Biological sciences Molecular Biology Physiology Immunology FOS Clinical medicine Biological Sciences not elsewhere classified Science Policy Chen, Hao Wang, Lingling Zhou, Zhi Hou, Zhanhui Liu, Zhaoqun Wang, Weilin Gao, Dahai Gao, Qiang Wang, Mengqiang Song, Linsheng The comprehensive immunomodulation of NeurimmiRs in haemocytes of oyster Crassostrea gigas after acetylcholine and norepinephrine stimulation ... |
topic_facet |
Medicine Genetics FOS Biological sciences Molecular Biology Physiology Immunology FOS Clinical medicine Biological Sciences not elsewhere classified Science Policy |
description |
Abstract Background Neural-endocrine-immune (NEI) system is a major modulation network among the nervous, endocrine and immune system and weights greatly in maintaining homeostasis of organisms during stress and infection. Some microRNAs are found interacting with NEI system (designated NeurimmiRs), addressing swift modulations on immune system. The oyster Crassostrea gigas, as an intertidal bivalve, has evolved a primary NEI system. However, the knowledge about NeurimmiRs in oysters remains largely unknown. Results Six small RNA libraries from haemocytes of oysters stimulated with acetylcholine (ACh) and norepinephrine (NE) were sequenced to identify neurotransmitter-responsive miRNAs and survey their immunomodulation roles. A total of 331 miRNAs (132 identified in the present study plus 199 identified previously) were subjected to expression analysis, and twenty-one and sixteen of them were found ACh- or NE-responsive, respectively (FDR < 0.05). Meanwhile, 21 miRNAs exhibited different expression ... |
format |
Article in Journal/Newspaper |
author |
Chen, Hao Wang, Lingling Zhou, Zhi Hou, Zhanhui Liu, Zhaoqun Wang, Weilin Gao, Dahai Gao, Qiang Wang, Mengqiang Song, Linsheng |
author_facet |
Chen, Hao Wang, Lingling Zhou, Zhi Hou, Zhanhui Liu, Zhaoqun Wang, Weilin Gao, Dahai Gao, Qiang Wang, Mengqiang Song, Linsheng |
author_sort |
Chen, Hao |
title |
The comprehensive immunomodulation of NeurimmiRs in haemocytes of oyster Crassostrea gigas after acetylcholine and norepinephrine stimulation ... |
title_short |
The comprehensive immunomodulation of NeurimmiRs in haemocytes of oyster Crassostrea gigas after acetylcholine and norepinephrine stimulation ... |
title_full |
The comprehensive immunomodulation of NeurimmiRs in haemocytes of oyster Crassostrea gigas after acetylcholine and norepinephrine stimulation ... |
title_fullStr |
The comprehensive immunomodulation of NeurimmiRs in haemocytes of oyster Crassostrea gigas after acetylcholine and norepinephrine stimulation ... |
title_full_unstemmed |
The comprehensive immunomodulation of NeurimmiRs in haemocytes of oyster Crassostrea gigas after acetylcholine and norepinephrine stimulation ... |
title_sort |
comprehensive immunomodulation of neurimmirs in haemocytes of oyster crassostrea gigas after acetylcholine and norepinephrine stimulation ... |
publisher |
figshare |
publishDate |
2015 |
url |
https://dx.doi.org/10.6084/m9.figshare.c.3605885 https://springernature.figshare.com/collections/The_comprehensive_immunomodulation_of_NeurimmiRs_in_haemocytes_of_oyster_Crassostrea_gigas_after_acetylcholine_and_norepinephrine_stimulation/3605885 |
genre |
Crassostrea gigas |
genre_facet |
Crassostrea gigas |
op_rights |
Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 |
op_doi |
https://doi.org/10.6084/m9.figshare.c.3605885 |
_version_ |
1797581561026052096 |