Supplementary material from "How the European eel ( Anguilla anguilla ) loses its skeletal framework across lifetime"
European eels ( Anguilla anguilla ) undertake an impressive 5000 km long migration from European fresh waters through the North Atlantic Ocean to the Sargasso Sea. Along with the sexual maturation, eel skeleton undergoes a remarkable morphological transformation during migration, where a hitherto co...
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ftdatacite:10.6084/m9.figshare.c.3500430 2023-05-15T13:27:11+02:00 Supplementary material from "How the European eel ( Anguilla anguilla ) loses its skeletal framework across lifetime" Rolvien, Tim Nagel, Florian Milovanovic, Petar Wuertz, Sven Marshall, Robert Percy Jeschke, Anke Schmidt, Felix N. Hahn, Michael P. Eckhard Witten Amling, Michael Busse, Björn 2016 https://dx.doi.org/10.6084/m9.figshare.c.3500430 https://figshare.com/collections/Supplementary_material_from_How_the_European_eel_i_Anguilla_anguilla_i_loses_its_skeletal_framework_across_lifetime_/3500430 unknown Figshare https://dx.doi.org/10.1098/rspb.2016.1550 CC-BY https://creativecommons.org/licenses/by/4.0 CC-BY Cell Biology Biological Engineering 110601 Biomechanics FOS Health sciences Collection article 2016 ftdatacite https://doi.org/10.6084/m9.figshare.c.3500430 https://doi.org/10.1098/rspb.2016.1550 2021-11-05T12:55:41Z European eels ( Anguilla anguilla ) undertake an impressive 5000 km long migration from European fresh waters through the North Atlantic Ocean to the Sargasso Sea. Along with the sexual maturation, eel skeleton undergoes a remarkable morphological transformation during migration, where a hitherto completely obscure bone loss phenomenon occurs. To unravel mechanisms of the maturation-related decay of the skeleton, we performed a multiscale assessment of eels' bones at different life-cycle stages. Accordingly, eel skeleton reflects extensive bone loss that is mediated via multinucleated bone-resorbing osteoclasts, while other resorption mechanisms such as osteocytic osteolysis or matrix demineralization were not observed. Preserving mechanical stability and releasing minerals for energy metabolism are two mutually exclusive functions of the skeleton that are orchestrated in eels through the presence of two spatially segregated hard tissues: cellular bone and acellular notochord. The cellular bone serves for mineral release following osteoclastic resorption, whereas the mineralized notochord sheath, that is inaccessible for resorption processes due to an unmineralized cover layer, ensures sufficient mechanical stability as a part of the notochord sheath. Clearly, eels' skeleton is structurally optimized to meet the metabolic challenge of fasting and simultaneous sexual development during an exhausting journey to the spawning areas, while the function of the vertebral column is maintained to achieve this goal. Article in Journal/Newspaper Anguilla anguilla North Atlantic DataCite Metadata Store (German National Library of Science and Technology) |
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DataCite Metadata Store (German National Library of Science and Technology) |
op_collection_id |
ftdatacite |
language |
unknown |
topic |
Cell Biology Biological Engineering 110601 Biomechanics FOS Health sciences |
spellingShingle |
Cell Biology Biological Engineering 110601 Biomechanics FOS Health sciences Rolvien, Tim Nagel, Florian Milovanovic, Petar Wuertz, Sven Marshall, Robert Percy Jeschke, Anke Schmidt, Felix N. Hahn, Michael P. Eckhard Witten Amling, Michael Busse, Björn Supplementary material from "How the European eel ( Anguilla anguilla ) loses its skeletal framework across lifetime" |
topic_facet |
Cell Biology Biological Engineering 110601 Biomechanics FOS Health sciences |
description |
European eels ( Anguilla anguilla ) undertake an impressive 5000 km long migration from European fresh waters through the North Atlantic Ocean to the Sargasso Sea. Along with the sexual maturation, eel skeleton undergoes a remarkable morphological transformation during migration, where a hitherto completely obscure bone loss phenomenon occurs. To unravel mechanisms of the maturation-related decay of the skeleton, we performed a multiscale assessment of eels' bones at different life-cycle stages. Accordingly, eel skeleton reflects extensive bone loss that is mediated via multinucleated bone-resorbing osteoclasts, while other resorption mechanisms such as osteocytic osteolysis or matrix demineralization were not observed. Preserving mechanical stability and releasing minerals for energy metabolism are two mutually exclusive functions of the skeleton that are orchestrated in eels through the presence of two spatially segregated hard tissues: cellular bone and acellular notochord. The cellular bone serves for mineral release following osteoclastic resorption, whereas the mineralized notochord sheath, that is inaccessible for resorption processes due to an unmineralized cover layer, ensures sufficient mechanical stability as a part of the notochord sheath. Clearly, eels' skeleton is structurally optimized to meet the metabolic challenge of fasting and simultaneous sexual development during an exhausting journey to the spawning areas, while the function of the vertebral column is maintained to achieve this goal. |
format |
Article in Journal/Newspaper |
author |
Rolvien, Tim Nagel, Florian Milovanovic, Petar Wuertz, Sven Marshall, Robert Percy Jeschke, Anke Schmidt, Felix N. Hahn, Michael P. Eckhard Witten Amling, Michael Busse, Björn |
author_facet |
Rolvien, Tim Nagel, Florian Milovanovic, Petar Wuertz, Sven Marshall, Robert Percy Jeschke, Anke Schmidt, Felix N. Hahn, Michael P. Eckhard Witten Amling, Michael Busse, Björn |
author_sort |
Rolvien, Tim |
title |
Supplementary material from "How the European eel ( Anguilla anguilla ) loses its skeletal framework across lifetime" |
title_short |
Supplementary material from "How the European eel ( Anguilla anguilla ) loses its skeletal framework across lifetime" |
title_full |
Supplementary material from "How the European eel ( Anguilla anguilla ) loses its skeletal framework across lifetime" |
title_fullStr |
Supplementary material from "How the European eel ( Anguilla anguilla ) loses its skeletal framework across lifetime" |
title_full_unstemmed |
Supplementary material from "How the European eel ( Anguilla anguilla ) loses its skeletal framework across lifetime" |
title_sort |
supplementary material from "how the european eel ( anguilla anguilla ) loses its skeletal framework across lifetime" |
publisher |
Figshare |
publishDate |
2016 |
url |
https://dx.doi.org/10.6084/m9.figshare.c.3500430 https://figshare.com/collections/Supplementary_material_from_How_the_European_eel_i_Anguilla_anguilla_i_loses_its_skeletal_framework_across_lifetime_/3500430 |
genre |
Anguilla anguilla North Atlantic |
genre_facet |
Anguilla anguilla North Atlantic |
op_relation |
https://dx.doi.org/10.1098/rspb.2016.1550 |
op_rights |
CC-BY https://creativecommons.org/licenses/by/4.0 |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.6084/m9.figshare.c.3500430 https://doi.org/10.1098/rspb.2016.1550 |
_version_ |
1766396927446876160 |