Secondary metabolites from Antarctic marine-derived fungus Penicillium crustosum HDN153086
A new polyene compound ( 1 ) and a new diketopiperazine ( 2 ), as well as three known compounds ( 3 – 5 ), were isolated from the Antarctic marine-derived fungus Penicillium crustosum HDN153086. The structures of 1 – 5 were deduced based on MS, NMR and TD-DFT calculations of specific ECD spectra. Th...
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ftdatacite:10.6084/m9.figshare.6067418.v1 2023-05-15T13:37:52+02:00 Secondary metabolites from Antarctic marine-derived fungus Penicillium crustosum HDN153086 Cong-Cong Liu Zhang, Zhen-Zhen Feng, Yan-Yan Qian-Qun Gu Li, De-Hai Zhu, Tian-Jiao 2018 https://dx.doi.org/10.6084/m9.figshare.6067418.v1 https://tandf.figshare.com/articles/Secondary_metabolites_from_Antarctic_marine-derived_fungus_i_Penicillium_crustosum_i_HDN153086/6067418/1 unknown Taylor & Francis https://dx.doi.org/10.1080/14786419.2018.1455045 https://dx.doi.org/10.6084/m9.figshare.6067418 Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 CC-BY Biochemistry Microbiology FOS Biological sciences Neuroscience Pharmacology 59999 Environmental Sciences not elsewhere classified FOS Earth and related environmental sciences 39999 Chemical Sciences not elsewhere classified FOS Chemical sciences Ecology Inorganic Chemistry Plant Biology 60506 Virology Text article-journal Journal contribution ScholarlyArticle 2018 ftdatacite https://doi.org/10.6084/m9.figshare.6067418.v1 https://doi.org/10.1080/14786419.2018.1455045 https://doi.org/10.6084/m9.figshare.6067418 2021-11-05T12:55:41Z A new polyene compound ( 1 ) and a new diketopiperazine ( 2 ), as well as three known compounds ( 3 – 5 ), were isolated from the Antarctic marine-derived fungus Penicillium crustosum HDN153086. The structures of 1 – 5 were deduced based on MS, NMR and TD-DFT calculations of specific ECD spectra. These compounds were evaluated for their cytotoxic activities against K562 cell line and only compound 2 exhibited cytotoxicity against K562 cell, with IC 50 value of 12.7 μM. Text Antarc* Antarctic DataCite Metadata Store (German National Library of Science and Technology) Antarctic The Antarctic |
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DataCite Metadata Store (German National Library of Science and Technology) |
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unknown |
topic |
Biochemistry Microbiology FOS Biological sciences Neuroscience Pharmacology 59999 Environmental Sciences not elsewhere classified FOS Earth and related environmental sciences 39999 Chemical Sciences not elsewhere classified FOS Chemical sciences Ecology Inorganic Chemistry Plant Biology 60506 Virology |
spellingShingle |
Biochemistry Microbiology FOS Biological sciences Neuroscience Pharmacology 59999 Environmental Sciences not elsewhere classified FOS Earth and related environmental sciences 39999 Chemical Sciences not elsewhere classified FOS Chemical sciences Ecology Inorganic Chemistry Plant Biology 60506 Virology Cong-Cong Liu Zhang, Zhen-Zhen Feng, Yan-Yan Qian-Qun Gu Li, De-Hai Zhu, Tian-Jiao Secondary metabolites from Antarctic marine-derived fungus Penicillium crustosum HDN153086 |
topic_facet |
Biochemistry Microbiology FOS Biological sciences Neuroscience Pharmacology 59999 Environmental Sciences not elsewhere classified FOS Earth and related environmental sciences 39999 Chemical Sciences not elsewhere classified FOS Chemical sciences Ecology Inorganic Chemistry Plant Biology 60506 Virology |
description |
A new polyene compound ( 1 ) and a new diketopiperazine ( 2 ), as well as three known compounds ( 3 – 5 ), were isolated from the Antarctic marine-derived fungus Penicillium crustosum HDN153086. The structures of 1 – 5 were deduced based on MS, NMR and TD-DFT calculations of specific ECD spectra. These compounds were evaluated for their cytotoxic activities against K562 cell line and only compound 2 exhibited cytotoxicity against K562 cell, with IC 50 value of 12.7 μM. |
format |
Text |
author |
Cong-Cong Liu Zhang, Zhen-Zhen Feng, Yan-Yan Qian-Qun Gu Li, De-Hai Zhu, Tian-Jiao |
author_facet |
Cong-Cong Liu Zhang, Zhen-Zhen Feng, Yan-Yan Qian-Qun Gu Li, De-Hai Zhu, Tian-Jiao |
author_sort |
Cong-Cong Liu |
title |
Secondary metabolites from Antarctic marine-derived fungus Penicillium crustosum HDN153086 |
title_short |
Secondary metabolites from Antarctic marine-derived fungus Penicillium crustosum HDN153086 |
title_full |
Secondary metabolites from Antarctic marine-derived fungus Penicillium crustosum HDN153086 |
title_fullStr |
Secondary metabolites from Antarctic marine-derived fungus Penicillium crustosum HDN153086 |
title_full_unstemmed |
Secondary metabolites from Antarctic marine-derived fungus Penicillium crustosum HDN153086 |
title_sort |
secondary metabolites from antarctic marine-derived fungus penicillium crustosum hdn153086 |
publisher |
Taylor & Francis |
publishDate |
2018 |
url |
https://dx.doi.org/10.6084/m9.figshare.6067418.v1 https://tandf.figshare.com/articles/Secondary_metabolites_from_Antarctic_marine-derived_fungus_i_Penicillium_crustosum_i_HDN153086/6067418/1 |
geographic |
Antarctic The Antarctic |
geographic_facet |
Antarctic The Antarctic |
genre |
Antarc* Antarctic |
genre_facet |
Antarc* Antarctic |
op_relation |
https://dx.doi.org/10.1080/14786419.2018.1455045 https://dx.doi.org/10.6084/m9.figshare.6067418 |
op_rights |
Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.6084/m9.figshare.6067418.v1 https://doi.org/10.1080/14786419.2018.1455045 https://doi.org/10.6084/m9.figshare.6067418 |
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