Dataset for: Human physiological and metabolic responses to an attempted winter crossing of Antarctica: the effects of prolonged hypobaric hypoxia.
An insufficient supply of oxygen to the tissues (hypoxia), as is experienced upon high altitude exposure, elicits physiological acclimatisation mechanisms alongside metabolic remodelling. Details of the integrative adaptive processes in response to chronic hypobaric hypoxic exposure remain to be suf...
Main Authors: | , , , , , , , , , |
---|---|
Format: | Dataset |
Language: | unknown |
Published: |
Wiley
2018
|
Subjects: | |
Online Access: | https://dx.doi.org/10.6084/m9.figshare.5821626 https://wiley.figshare.com/articles/Dataset_for_Human_physiological_and_metabolic_responses_to_an_attempted_winter_crossing_of_Antarctica_the_effects_of_prolonged_hypobaric_hypoxia_/5821626 |
id |
ftdatacite:10.6084/m9.figshare.5821626 |
---|---|
record_format |
openpolar |
spelling |
ftdatacite:10.6084/m9.figshare.5821626 2023-05-15T14:02:56+02:00 Dataset for: Human physiological and metabolic responses to an attempted winter crossing of Antarctica: the effects of prolonged hypobaric hypoxia. O'Brien, Katie A Pollock, Ross D Stroud, Mike A Lambert, Rob J Kumar, Alex Atkinson, Robert A Green, David A Anton-Solanas, Ana Edwards, Lindsay M Harridge, Steve D.R. 2018 https://dx.doi.org/10.6084/m9.figshare.5821626 https://wiley.figshare.com/articles/Dataset_for_Human_physiological_and_metabolic_responses_to_an_attempted_winter_crossing_of_Antarctica_the_effects_of_prolonged_hypobaric_hypoxia_/5821626 unknown Wiley https://dx.doi.org/10.14814/phy2.13613 Creative Commons Zero v1.0 Universal https://creativecommons.org/publicdomain/zero/1.0/legalcode cc0-1.0 CC0 Physiology FOS Biological sciences 60114 Systems Biology dataset Dataset 2018 ftdatacite https://doi.org/10.6084/m9.figshare.5821626 https://doi.org/10.14814/phy2.13613 2021-11-05T12:55:41Z An insufficient supply of oxygen to the tissues (hypoxia), as is experienced upon high altitude exposure, elicits physiological acclimatisation mechanisms alongside metabolic remodelling. Details of the integrative adaptive processes in response to chronic hypobaric hypoxic exposure remain to be sufficiently investigated. In this small applied field study, subjects (n=5, male, age 28-54 yrs) undertook a 40 week Antarctica expedition in the winter months, which included 24 weeks residing above 2500m. Measurements taken pre and post expedition revealed alterations to glucose and fatty acid resonances within the serum metabolic profile, a 7.8 (+ 3.6) % increase in respiratory exchange ratio measured during incremental exercise (area under curve, p>0.01, mean ±SD) and a 2.1(+ 0.8) % decrease in fat tissue (p<0.05) post expedition. This was accompanied by an 11.6 (+1.9) % increase (p>0.001) in VO2 max corrected to % lean mass post expedition. In addition, spine bone mineral density and lung function measures were identified as novel parameters of interest. This study provides, an in-depth characterisation of the responses to chronic hypobaric hypoxic exposure in one of the most hostile environments on Earth. Dataset Antarc* Antarctica DataCite Metadata Store (German National Library of Science and Technology) |
institution |
Open Polar |
collection |
DataCite Metadata Store (German National Library of Science and Technology) |
op_collection_id |
ftdatacite |
language |
unknown |
topic |
Physiology FOS Biological sciences 60114 Systems Biology |
spellingShingle |
Physiology FOS Biological sciences 60114 Systems Biology O'Brien, Katie A Pollock, Ross D Stroud, Mike A Lambert, Rob J Kumar, Alex Atkinson, Robert A Green, David A Anton-Solanas, Ana Edwards, Lindsay M Harridge, Steve D.R. Dataset for: Human physiological and metabolic responses to an attempted winter crossing of Antarctica: the effects of prolonged hypobaric hypoxia. |
topic_facet |
Physiology FOS Biological sciences 60114 Systems Biology |
description |
An insufficient supply of oxygen to the tissues (hypoxia), as is experienced upon high altitude exposure, elicits physiological acclimatisation mechanisms alongside metabolic remodelling. Details of the integrative adaptive processes in response to chronic hypobaric hypoxic exposure remain to be sufficiently investigated. In this small applied field study, subjects (n=5, male, age 28-54 yrs) undertook a 40 week Antarctica expedition in the winter months, which included 24 weeks residing above 2500m. Measurements taken pre and post expedition revealed alterations to glucose and fatty acid resonances within the serum metabolic profile, a 7.8 (+ 3.6) % increase in respiratory exchange ratio measured during incremental exercise (area under curve, p>0.01, mean ±SD) and a 2.1(+ 0.8) % decrease in fat tissue (p<0.05) post expedition. This was accompanied by an 11.6 (+1.9) % increase (p>0.001) in VO2 max corrected to % lean mass post expedition. In addition, spine bone mineral density and lung function measures were identified as novel parameters of interest. This study provides, an in-depth characterisation of the responses to chronic hypobaric hypoxic exposure in one of the most hostile environments on Earth. |
format |
Dataset |
author |
O'Brien, Katie A Pollock, Ross D Stroud, Mike A Lambert, Rob J Kumar, Alex Atkinson, Robert A Green, David A Anton-Solanas, Ana Edwards, Lindsay M Harridge, Steve D.R. |
author_facet |
O'Brien, Katie A Pollock, Ross D Stroud, Mike A Lambert, Rob J Kumar, Alex Atkinson, Robert A Green, David A Anton-Solanas, Ana Edwards, Lindsay M Harridge, Steve D.R. |
author_sort |
O'Brien, Katie A |
title |
Dataset for: Human physiological and metabolic responses to an attempted winter crossing of Antarctica: the effects of prolonged hypobaric hypoxia. |
title_short |
Dataset for: Human physiological and metabolic responses to an attempted winter crossing of Antarctica: the effects of prolonged hypobaric hypoxia. |
title_full |
Dataset for: Human physiological and metabolic responses to an attempted winter crossing of Antarctica: the effects of prolonged hypobaric hypoxia. |
title_fullStr |
Dataset for: Human physiological and metabolic responses to an attempted winter crossing of Antarctica: the effects of prolonged hypobaric hypoxia. |
title_full_unstemmed |
Dataset for: Human physiological and metabolic responses to an attempted winter crossing of Antarctica: the effects of prolonged hypobaric hypoxia. |
title_sort |
dataset for: human physiological and metabolic responses to an attempted winter crossing of antarctica: the effects of prolonged hypobaric hypoxia. |
publisher |
Wiley |
publishDate |
2018 |
url |
https://dx.doi.org/10.6084/m9.figshare.5821626 https://wiley.figshare.com/articles/Dataset_for_Human_physiological_and_metabolic_responses_to_an_attempted_winter_crossing_of_Antarctica_the_effects_of_prolonged_hypobaric_hypoxia_/5821626 |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_relation |
https://dx.doi.org/10.14814/phy2.13613 |
op_rights |
Creative Commons Zero v1.0 Universal https://creativecommons.org/publicdomain/zero/1.0/legalcode cc0-1.0 |
op_rightsnorm |
CC0 |
op_doi |
https://doi.org/10.6084/m9.figshare.5821626 https://doi.org/10.14814/phy2.13613 |
_version_ |
1766273396717387776 |