Additional file 1 of Hypoxia exposure blunts angiogenic signaling and upregulates the antioxidant system in endothelial cells derived from elephant seals ...
Additional file 1: Supplementary Figures S1-S6. Figure S1. Representative images for mitochondrial staining after 0, 1, or 6 h hypoxia exposure followed by 30 min reoxygenation. Upper: seal. Lower: human. MitoTracker Red CMXRos (red). Hoescht (blue). Scale bar is 50 µm. Figure S2. Uncropped western...
| Main Authors: | , , , , , |
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| Format: | Text |
| Language: | unknown |
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figshare
2024
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| Subjects: | |
| Online Access: | https://dx.doi.org/10.6084/m9.figshare.25678610.v1 https://springernature.figshare.com/articles/journal_contribution/Additional_file_1_of_Hypoxia_exposure_blunts_angiogenic_signaling_and_upregulates_the_antioxidant_system_in_endothelial_cells_derived_from_elephant_seals/25678610/1 |
| Summary: | Additional file 1: Supplementary Figures S1-S6. Figure S1. Representative images for mitochondrial staining after 0, 1, or 6 h hypoxia exposure followed by 30 min reoxygenation. Upper: seal. Lower: human. MitoTracker Red CMXRos (red). Hoescht (blue). Scale bar is 50 µm. Figure S2. Uncropped western blots. (A) HIF-1α. (B) β-actin. Figure S3. Raw gap area for all species and conditions during scratch assay. Figure S4. Total within cluster sum of squares for clustering results from k=1...30). Upper: seal. Lower: human. Diminishing returns were observed after 6 clusters thus k=6 (pink) was selected as the optimal clustering. Figure S5. k-means clustering and KEGG pathway enrichment for human cells. k-means clustering of gene expression data for human cells exposed to 1% O2 for up to 6 h. (B) KEGG pathway enrichment for human clusters. Numbers on the right axis correspond to human cluster numbers. Figure S6. Long-term hypoxia exposure modulates transcription and translation in human cells. (A) Reactome pathway ... |
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