Evolution, characterization, and expression profile of Egl-9 family hypoxia-inducible factor ( egln ) in rainbow trout ( Oncorhynchus mykiss ) under hypoxia stress ...
Egl-9 family hypoxia-inducible factor ( egln ), an oxygen-sensing enzyme family, has been thoroughly characterized in mammals and certain fishes, but there is few research on its involvement in reproductive development and hypoxic stress in rainbow trout. In this study, we investigated the gene stru...
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Taylor & Francis
2022
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Online Access: | https://dx.doi.org/10.6084/m9.figshare.19361887 https://tandf.figshare.com/articles/dataset/Evolution_characterization_and_expression_profile_of_Egl-9_family_hypoxia-inducible_factor_i_egln_i_in_rainbow_trout_i_Oncorhynchus_mykiss_i_under_hypoxia_stress/19361887 |
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ftdatacite:10.6084/m9.figshare.19361887 2023-12-03T10:19:39+01:00 Evolution, characterization, and expression profile of Egl-9 family hypoxia-inducible factor ( egln ) in rainbow trout ( Oncorhynchus mykiss ) under hypoxia stress ... Ma, Fang Zou, Yali Chen, Xin Ma, Lanfang Ma, Ruilin 2022 https://dx.doi.org/10.6084/m9.figshare.19361887 https://tandf.figshare.com/articles/dataset/Evolution_characterization_and_expression_profile_of_Egl-9_family_hypoxia-inducible_factor_i_egln_i_in_rainbow_trout_i_Oncorhynchus_mykiss_i_under_hypoxia_stress/19361887 unknown Taylor & Francis https://dx.doi.org/10.1080/10495398.2022.2047994 Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 Biochemistry Cell Biology Genetics FOS Biological sciences Molecular Biology Evolutionary Biology Immunology FOS Clinical medicine Biological Sciences not elsewhere classified Cancer Inorganic Chemistry FOS Chemical sciences Computational Biology dataset Dataset 2022 ftdatacite https://doi.org/10.6084/m9.figshare.1936188710.1080/10495398.2022.2047994 2023-11-03T10:53:49Z Egl-9 family hypoxia-inducible factor ( egln ), an oxygen-sensing enzyme family, has been thoroughly characterized in mammals and certain fishes, but there is few research on its involvement in reproductive development and hypoxic stress in rainbow trout. In this study, we investigated the gene structure, physicochemical properties, and evolutionary connection of the egln gene family. The expression profile of egln gene family and their regulatory mechanism were explored using bioinformatics analysis and hypoxia treatment experiments. Five egln genes were discovered in the rainbow trout genome in this investigation ( egln1 , egln2a , egln2b , egln3a , and egln3b ). Domain prediction revealed that all egln proteins have p4hc conserved domains, and phylogenetic analysis revealed that rainbow trout egln2 and egln3 were closely related to Atlantic salmon . The results of real-time quantitative PCR (RT-qPCR) showed that egln genes were generally expressed in all detected tissues, and higher in the ovary, testis, ... Dataset Atlantic salmon DataCite Metadata Store (German National Library of Science and Technology) |
institution |
Open Polar |
collection |
DataCite Metadata Store (German National Library of Science and Technology) |
op_collection_id |
ftdatacite |
language |
unknown |
topic |
Biochemistry Cell Biology Genetics FOS Biological sciences Molecular Biology Evolutionary Biology Immunology FOS Clinical medicine Biological Sciences not elsewhere classified Cancer Inorganic Chemistry FOS Chemical sciences Computational Biology |
spellingShingle |
Biochemistry Cell Biology Genetics FOS Biological sciences Molecular Biology Evolutionary Biology Immunology FOS Clinical medicine Biological Sciences not elsewhere classified Cancer Inorganic Chemistry FOS Chemical sciences Computational Biology Ma, Fang Zou, Yali Chen, Xin Ma, Lanfang Ma, Ruilin Evolution, characterization, and expression profile of Egl-9 family hypoxia-inducible factor ( egln ) in rainbow trout ( Oncorhynchus mykiss ) under hypoxia stress ... |
topic_facet |
Biochemistry Cell Biology Genetics FOS Biological sciences Molecular Biology Evolutionary Biology Immunology FOS Clinical medicine Biological Sciences not elsewhere classified Cancer Inorganic Chemistry FOS Chemical sciences Computational Biology |
description |
Egl-9 family hypoxia-inducible factor ( egln ), an oxygen-sensing enzyme family, has been thoroughly characterized in mammals and certain fishes, but there is few research on its involvement in reproductive development and hypoxic stress in rainbow trout. In this study, we investigated the gene structure, physicochemical properties, and evolutionary connection of the egln gene family. The expression profile of egln gene family and their regulatory mechanism were explored using bioinformatics analysis and hypoxia treatment experiments. Five egln genes were discovered in the rainbow trout genome in this investigation ( egln1 , egln2a , egln2b , egln3a , and egln3b ). Domain prediction revealed that all egln proteins have p4hc conserved domains, and phylogenetic analysis revealed that rainbow trout egln2 and egln3 were closely related to Atlantic salmon . The results of real-time quantitative PCR (RT-qPCR) showed that egln genes were generally expressed in all detected tissues, and higher in the ovary, testis, ... |
format |
Dataset |
author |
Ma, Fang Zou, Yali Chen, Xin Ma, Lanfang Ma, Ruilin |
author_facet |
Ma, Fang Zou, Yali Chen, Xin Ma, Lanfang Ma, Ruilin |
author_sort |
Ma, Fang |
title |
Evolution, characterization, and expression profile of Egl-9 family hypoxia-inducible factor ( egln ) in rainbow trout ( Oncorhynchus mykiss ) under hypoxia stress ... |
title_short |
Evolution, characterization, and expression profile of Egl-9 family hypoxia-inducible factor ( egln ) in rainbow trout ( Oncorhynchus mykiss ) under hypoxia stress ... |
title_full |
Evolution, characterization, and expression profile of Egl-9 family hypoxia-inducible factor ( egln ) in rainbow trout ( Oncorhynchus mykiss ) under hypoxia stress ... |
title_fullStr |
Evolution, characterization, and expression profile of Egl-9 family hypoxia-inducible factor ( egln ) in rainbow trout ( Oncorhynchus mykiss ) under hypoxia stress ... |
title_full_unstemmed |
Evolution, characterization, and expression profile of Egl-9 family hypoxia-inducible factor ( egln ) in rainbow trout ( Oncorhynchus mykiss ) under hypoxia stress ... |
title_sort |
evolution, characterization, and expression profile of egl-9 family hypoxia-inducible factor ( egln ) in rainbow trout ( oncorhynchus mykiss ) under hypoxia stress ... |
publisher |
Taylor & Francis |
publishDate |
2022 |
url |
https://dx.doi.org/10.6084/m9.figshare.19361887 https://tandf.figshare.com/articles/dataset/Evolution_characterization_and_expression_profile_of_Egl-9_family_hypoxia-inducible_factor_i_egln_i_in_rainbow_trout_i_Oncorhynchus_mykiss_i_under_hypoxia_stress/19361887 |
genre |
Atlantic salmon |
genre_facet |
Atlantic salmon |
op_relation |
https://dx.doi.org/10.1080/10495398.2022.2047994 |
op_rights |
Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 |
op_doi |
https://doi.org/10.6084/m9.figshare.1936188710.1080/10495398.2022.2047994 |
_version_ |
1784267008208011264 |