Genomic data from an extinct Palaeo-Eskimo

• Main Authors: Rasmussen, M, Li, Y, Lindgreen, S, Pedersen, JS, Albrechtsen, A, Moltke, I, Metspalu, M, Metspalu, E, Kivisild, T, Gupta, R, Bertalan, M, Nielsen, K, Gilbert, MT, Wang, Y, Raghavan, M, Campos, PF, Kamp, HM, Wilson, AS, Gledhill, A, Tridico, S, Bunce, M, Lorenzen, ED, Binladen, J, Guo, X, Zhao, J, Zhang, X, Zhang, H, Li, Z, Chen, M, Orlando, L, Kristiansen, K, Bak, M, Tommerup, N, Bendixen, C, Pierre, TL, Gronnow, B, Meldgaard, M, Andreasen, C, Fedorova, SA, Osipova, LP, Higham, TF, Ramsey, CB, Hansen, TV, Nielsen, FC, Crawford, MH, Brunak, S, Sicheritz-Ponten, T, Villems, R, Nielsen, R, Krogh, A, Wang, J, Willerslev, E
• Format: Dataset
• Language: English
• Published: GigaScience 2011
• Subjects: Genomic; Greenland; eskimo*; permafrost
• Online Access: https://dx.doi.org/10.5524/100026; http://gigadb.org/dataset/100026

Available here is the genome of a male individual from an extinct Palaeo-Eskimo culture, the first known group of Homo sapiens to settle in Greenland. The DNA sample was obtained from ~4,000-year-old permafrost-preserved hair, and was shown to have very low modern DNA contamination. The diploid genome was sequenced to an average depth of 20x using Illumina GAII sequencing platforms, with 79% recovery. Correct indexed reads were mapped to the human genome (hg18) with a suffix array-based method that allows for residual primer trimming. Sequencing yielded a total of 3.5 billion reads.