NQO1 Enzyme and its Role in Cellular Protection; an Insight

• Main Authors: Atia, Ahmed, Azman Abdullah
• Format: Text
• Language: English
• Published: Zenodo 2020
• Subjects: Gene expression; NQO1; Keap1; ARE; Indian; Hayes; Burgess; Finley; Bolton; Bingham; McIntosh; Stephenson; Goodwin; Boland; McMahon; Colombo; O'Connor; Pickett; Barrios; Sherratt; inuit
• Online Access: https://dx.doi.org/10.5281/zenodo.3877527; https://zenodo.org/record/3877527

NAD(P)H:quinone oxidoreductase 1 (NQO1) is considered as one of the most significant enzyme in cellular defense due to its ability to detoxify reactive quinones and quinone imines to their less toxic hydroquinones forms. NQO1 is a xenobiotic metabolizing cytosolic enzyme that catalyzes the reduction...