The effect of allostatic load on hypothalamic-pituitary-interrenal (HPI) axis before and after secondary vaccination in Atlantic salmon postsmolts (Salmo salar L.) ...

• Main Authors: Iversen, Martin H., Eliassen, Robert A.
• Format: Article in Journal/Newspaper
• Language: unknown
• Published: Zenodo 2014
• Subjects: Allostatic load; Animal welfare; Chronic stress; HPI axis; Vaccination; carp cyprinus-carpio; common carp; cortisol response; dexamethasone suppression test; immune-system; plasma-cortisol; rainbow-trout; seabream sparus-aurata; stress-response; trout oncorhynchus-mykiss; Biodiversity; Mammalia; Chiroptera; Chordata; Animalia; bats; bat; Atlantic salmon; Salmo salar
• Online Access: https://dx.doi.org/10.5281/zenodo.13532827; https://zenodo.org/doi/10.5281/zenodo.13532827

(Uploaded by Plazi for the Bat Literature Project) The experiment consisted of three experimental groups: (1) "vaccine and stress", (2) "stress and vaccine" and (3) control. All groups have previously been vaccinated 6 months prior to the start of the experiment. At the start of the experiment, the "vaccine and stress" group was vaccinated with Pentium Forte Plus for the second time (25.02.2008) and then given a daily stressor (confinement stressor 267 kg m-3 in 15 min) for a period of 4 weeks. The "stress and vaccine" group was given a similar daily stressor for 4 weeks and then vaccinated for the second time. The control group was neither stressed nor vaccinated a second time. The results indicates that fish in the "stress and vaccine" group may have entered an allostatic overload type 2 due to oversensitivity to ACTH, a reduced efficient negative feedback system with elevated baseline levels of plasma cortisol and reduced immune response with pronounced effects on the well-being of the animal. The ...