Blue Light and Temperature Actigraphy Measures Predicting Metabolic Health Are Linked to Melatonin Receptor Polymorphism ...

• Main Authors: Gubin, Denis, Danilenko, Konstantin, Stefani, Oliver, Kolomeichuk, Sergey, Markov, Alexander, Petrov, Ivan, Voronin, Kirill, Mezhakova, Marina, Borisenkov, Mikhail, Shigabaeva, Aislu, Yuzhakova, Natalya, Lobkina, Svetlana, Weinert, Dietmar, Cornelissen, Germaine
• Format: Article in Journal/Newspaper
• Language: unknown
• Published: Zenodo 2023
• Subjects: Light; Arctic; Metabolism
• Online Access: https://dx.doi.org/10.5281/zenodo.12748919; https://zenodo.org/doi/10.5281/zenodo.12748919

This study explores the relationship between the light features of the Arctic spring equinox and circadian rhythms, sleep and metabolic health. Residents (N = 62) provided week-long actigraphy measures, including light exposure, which were related to body mass index (BMI), leptin and cortisol. Lower wrist temperature (wT) and higher evening blue light exposure (BLE), expressed as a novel index, the nocturnal excess index (NEIbl), were the most sensitive actigraphy measures associated with BMI. A higher BMI was linked to nocturnal BLE within distinct time windows. These associations were present specifically in carriers of the MTNR1B rs10830963 G-allele. A larger wake-after-sleep onset (WASO), smaller 24 h amplitude and earlier phase of the activity rhythm were associated with higher leptin. Higher cortisol was associated with an earlier M10 onset of BLE and with our other novel index, the Daylight Deficit Index of blue light, DDIbl. We also found sex-, age- and population-dependent differences in the ... : + ID der Publikation: hslu_107556 + Art des Beitrages: Wissenschaftliche Medien + Sprache: Englisch + Letzte Aktualisierung: 2024-07-16 10:46:29 ...