Data from: Evaluating the performance of selection scans to detect selective sweeps in domestic dogs ...

• Main Authors: Schlamp, Florencia, Van Der Made, Julian, Stambler, Rebecca, Chesebrough, Lewis, Boyko, Adam R., Messer, Philipp W.
• Format: Dataset
• Language: English
• Published: Dryad 2015
• Subjects: Canis lupus familiaris; Canis lupus; Contemporary Evolution
• Online Access: https://dx.doi.org/10.5061/dryad.hf46s; https://datadryad.org/stash/dataset/doi:10.5061/dryad.hf46s

Selective breeding of dogs has resulted in repeated artificial selection on breed-specific morphological phenotypes. A number of quantitative trait loci associated with these phenotypes have been identified in genetic mapping studies. We analyzed the population genomic signatures observed around the causal mutations for 12 of these loci in 25 dog breeds, for which we genotyped 25 individuals in each breed. By measuring the population frequencies of the causal mutations in each breed, we identified those breeds in which specific mutations most likely experienced positive selection. These instances were then used as positive controls for assessing the performance of popular statistics to detect selection from population genomic data. We found that artificial selection during dog domestication has left characteristic signatures in the haplotype and nucleotide polymorphism patterns around selected loci that can be detected in the genotype data from a single population sample. However, the sensitivity and ... : Raw Genotyping DataData from: Shannon et al. (2015) Genetic structure in village dogs reveals a Central Asian domestication origin. Dryad Digital Repository. http://dx.doi.org/10.5061/dryad.v9t5hImputed Data (.tfam)chr_1_to_38.imputed.tfamImputed Data (.tped)chr_1_to_38.imputed.tpedHapFLK ResultsHapFLK genome-wide results, chromosomes 1 to 38chr_1_to_38.hapflkiHS ResultsNormalized iHS results for chromosomes 1, 3, 4, 5, 10, 11, 15, 27, and 32iHS_results.zipnSL ResultsNormalized nSL results for chromosomes 1, 3, 4, 5, 10, 11, 15, 27, and 32nSL_results.zipH ResultsH results for chromosomes 1, 3, 4, 5, 10, 11, 15, 27, and 32H_results.zippi, Tajima's D, and H12 Resultspi, Tajima's D, and H12 results for chromosomes 1, 3, 4, 5, 10, 11, 15, 27, and 32, for window sizes of 25, 51, 101, and 201Window_Scans_results.zipCLR ResultsCLR results for chromosomes 1, 3, 4, 5, 10, 11, 15, 27, and 32CLR_results.zipSamples Identifier FileList of all samples used, with their sample codes and breedsamples.txt ...