Data from: Direct-to-consumer DNA testing of 6,000 dogs reveals 98.6-kb duplication associated with blue eyes and heterochromia in Siberian Huskies ...
Consumer genomics enables genetic discovery on an unprecedented scale by linking very large databases of personal genomic data with phenotype information voluntarily submitted via web-based surveys. These databases are having a transformative effect on human genomics research, yielding insights on i...
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ftdatacite:10.5061/dryad.h305b15 2024-10-13T14:06:33+00:00 Data from: Direct-to-consumer DNA testing of 6,000 dogs reveals 98.6-kb duplication associated with blue eyes and heterochromia in Siberian Huskies ... Deane-Coe, Petra E. Chu, Erin T. Slavney, Andrea Boyko, Adam R. Sams, Aaron J. 2019 https://dx.doi.org/10.5061/dryad.h305b15 https://datadryad.org/stash/dataset/doi:10.5061/dryad.h305b15 en eng Dryad https://dx.doi.org/10.1371/journal.pgen.1007648 Creative Commons Zero v1.0 Universal https://creativecommons.org/publicdomain/zero/1.0/legalcode cc0-1.0 Canis lupus familiaris Dataset dataset 2019 ftdatacite https://doi.org/10.5061/dryad.h305b1510.1371/journal.pgen.1007648 2024-10-01T11:13:55Z Consumer genomics enables genetic discovery on an unprecedented scale by linking very large databases of personal genomic data with phenotype information voluntarily submitted via web-based surveys. These databases are having a transformative effect on human genomics research, yielding insights on increasingly complex traits, behaviors, and disease by including many thousands of individuals in genome-wide association studies (GWAS). The promise of consumer genomic data is not limited to human research, however. Genomic tools for dogs are readily available, with hundreds of causal Mendelian variants already characterized, because selection and breeding have led to dramatic phenotypic diversity underlain by a simple genetic structure. Here, we report the results of the first consumer genomics study ever conducted in a non-human model: a GWAS of blue eyes based on more than 3,000 customer dogs with validation panels including nearly 3,000 more, the largest canine GWAS to date. We discovered a novel association ... : deane-coe_etal_canine_eye_color_GWASSupplemental data archive for Deane-Coe et al. "Direct-To-Consumer DNA testing of 6,000 dogs reveals 98.6-kb duplication causing blue eyes and heterochromia in Siberian Huskies." ... Dataset Canis lupus Huskies DataCite |
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Open Polar |
collection |
DataCite |
op_collection_id |
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English |
topic |
Canis lupus familiaris |
spellingShingle |
Canis lupus familiaris Deane-Coe, Petra E. Chu, Erin T. Slavney, Andrea Boyko, Adam R. Sams, Aaron J. Data from: Direct-to-consumer DNA testing of 6,000 dogs reveals 98.6-kb duplication associated with blue eyes and heterochromia in Siberian Huskies ... |
topic_facet |
Canis lupus familiaris |
description |
Consumer genomics enables genetic discovery on an unprecedented scale by linking very large databases of personal genomic data with phenotype information voluntarily submitted via web-based surveys. These databases are having a transformative effect on human genomics research, yielding insights on increasingly complex traits, behaviors, and disease by including many thousands of individuals in genome-wide association studies (GWAS). The promise of consumer genomic data is not limited to human research, however. Genomic tools for dogs are readily available, with hundreds of causal Mendelian variants already characterized, because selection and breeding have led to dramatic phenotypic diversity underlain by a simple genetic structure. Here, we report the results of the first consumer genomics study ever conducted in a non-human model: a GWAS of blue eyes based on more than 3,000 customer dogs with validation panels including nearly 3,000 more, the largest canine GWAS to date. We discovered a novel association ... : deane-coe_etal_canine_eye_color_GWASSupplemental data archive for Deane-Coe et al. "Direct-To-Consumer DNA testing of 6,000 dogs reveals 98.6-kb duplication causing blue eyes and heterochromia in Siberian Huskies." ... |
format |
Dataset |
author |
Deane-Coe, Petra E. Chu, Erin T. Slavney, Andrea Boyko, Adam R. Sams, Aaron J. |
author_facet |
Deane-Coe, Petra E. Chu, Erin T. Slavney, Andrea Boyko, Adam R. Sams, Aaron J. |
author_sort |
Deane-Coe, Petra E. |
title |
Data from: Direct-to-consumer DNA testing of 6,000 dogs reveals 98.6-kb duplication associated with blue eyes and heterochromia in Siberian Huskies ... |
title_short |
Data from: Direct-to-consumer DNA testing of 6,000 dogs reveals 98.6-kb duplication associated with blue eyes and heterochromia in Siberian Huskies ... |
title_full |
Data from: Direct-to-consumer DNA testing of 6,000 dogs reveals 98.6-kb duplication associated with blue eyes and heterochromia in Siberian Huskies ... |
title_fullStr |
Data from: Direct-to-consumer DNA testing of 6,000 dogs reveals 98.6-kb duplication associated with blue eyes and heterochromia in Siberian Huskies ... |
title_full_unstemmed |
Data from: Direct-to-consumer DNA testing of 6,000 dogs reveals 98.6-kb duplication associated with blue eyes and heterochromia in Siberian Huskies ... |
title_sort |
data from: direct-to-consumer dna testing of 6,000 dogs reveals 98.6-kb duplication associated with blue eyes and heterochromia in siberian huskies ... |
publisher |
Dryad |
publishDate |
2019 |
url |
https://dx.doi.org/10.5061/dryad.h305b15 https://datadryad.org/stash/dataset/doi:10.5061/dryad.h305b15 |
genre |
Canis lupus Huskies |
genre_facet |
Canis lupus Huskies |
op_relation |
https://dx.doi.org/10.1371/journal.pgen.1007648 |
op_rights |
Creative Commons Zero v1.0 Universal https://creativecommons.org/publicdomain/zero/1.0/legalcode cc0-1.0 |
op_doi |
https://doi.org/10.5061/dryad.h305b1510.1371/journal.pgen.1007648 |
_version_ |
1812812745090793472 |