Data from: Genetic subdivision and candidate genes under selection in North American gray wolves ...

• Main Authors: Schweizer, Rena M., VonHoldt, Bridgett M., Harrigan, Ryan, Knowles, James C., Musiani, Marco, Coltman, David, Novembre, John, Wayne, Robert K.
• Format: Dataset
• Language: English
• Published: Dryad 2015
• Subjects: Genomics/Proteomics; Holocene; Canis lupus; Arctic; gray wolf
• Online Access: https://dx.doi.org/10.5061/dryad.c9b25; https://datadryad.org/stash/dataset/doi:10.5061/dryad.c9b25

Previous genetic studies of the highly mobile gray wolf (Canis lupus) found population structure that coincides with habitat and phenotype differences. We hypothesized that these ecologically distinct populations (ecotypes) should exhibit signatures of selection in genes related to morphology, coat color, and metabolism. To test these predictions, we quantified population structure related to habitat using a genotyping array to assess variation in 42,036 SNPs in 111 North American gray wolves. Using these SNP data and individual-level measurements of 12 environmental variables, we identified six ecotypes: West Forest, Boreal Forest, Arctic, High Arctic, British Columbia, and Atlantic Forest. Next, we explored signals of selection across these wolf ecotypes through the use of three complementary methods to detect selection: FST/haplotype homozygosity bivariate percentile, BayeScan, and environmentally correlated directional selection with Bayenv. Across all methods, we found consistent signals of selection on ... : Environmental Data for 94 wolves in 6 populationsThese data represent latitude and longitude coordinates for the 94 wolves used in this study for selection tests. The 12 environmental variables for each coordinate were downloaded within ArcGIS from various WORLDCLIM databases (http://www.worldclim.org/). Please see descriptions on website for information on what each variable measures. From the website: "Please note that the temperature data are in °C * 10. This means that a value of 231 represents 23.1 °C. This does lead to some confusion, but it allows for much reduced file sizes which is important as for many downloading large files remains difficult. The unit used for the precipitation data is mm (millimeter)."EnvironmentalData_6pops_94indiv.xlsxnacanids_111indiv_unrel_noYNP_42Ksnps.tpedThe set of all 42,587 SNPs for 111 unrelated wolves, in PLINK .tped format. (http://pngu.mgh.harvard.edu/~purcell/plink/)nacanids_111indiv_unrel_noYNP_42Ksnps.tfamThe .tfam file, in PLINK format, that corresponds to ...