Wild pedigrees inform mutation rates and historic abundance in baleen whales ...
Phylogeny-based estimates suggesting a low germline mutation rate (μ) in baleen whales have influenced research ranging from assessments of whaling impacts to evolutionary cancer biology. We estimated μ directly from pedigrees in four baleen whale species for both the mitochondrial control region an...
Main Authors: | , , , , , , , , , , , |
---|---|
Format: | Dataset |
Language: | English |
Published: |
Dryad
2023
|
Subjects: | |
Online Access: | https://dx.doi.org/10.5061/dryad.9kd51c5pq https://datadryad.org/stash/dataset/doi:10.5061/dryad.9kd51c5pq |
id |
ftdatacite:10.5061/dryad.9kd51c5pq |
---|---|
record_format |
openpolar |
spelling |
ftdatacite:10.5061/dryad.9kd51c5pq 2024-02-04T09:59:07+01:00 Wild pedigrees inform mutation rates and historic abundance in baleen whales ... Suárez-Menéndez, Marcos Bérubé, Martine Furni, Fabrício Rivera-Leon, Vania Heide-Jørgensen, Mads Peter Larsen, Finn Sears, Richard Ramp, Christian Eriksson, Britas Klemens Etienne, Rampal Robbins, Jooke Palsbøll, Per 2023 https://dx.doi.org/10.5061/dryad.9kd51c5pq https://datadryad.org/stash/dataset/doi:10.5061/dryad.9kd51c5pq en eng Dryad https://dx.doi.org/10.1101/2022.10.06.510775 https://dx.doi.org/10.1126/science.adf2160 Creative Commons Zero v1.0 Universal https://creativecommons.org/publicdomain/zero/1.0/legalcode cc0-1.0 pedigree baleen whales FOS Biological sciences mutation rate Dataset dataset 2023 ftdatacite https://doi.org/10.5061/dryad.9kd51c5pq10.1101/2022.10.06.51077510.1126/science.adf2160 2024-01-05T04:39:59Z Phylogeny-based estimates suggesting a low germline mutation rate (μ) in baleen whales have influenced research ranging from assessments of whaling impacts to evolutionary cancer biology. We estimated μ directly from pedigrees in four baleen whale species for both the mitochondrial control region and nuclear genome. The results suggest values higher than those obtained through phylogeny-based estimates and similar to pedigree-based values for primates and toothed whales. Applying our estimate of μ reduces previous genetic–based estimates of pre-exploitation whale abundance by 86% and suggests that μ cannot explain low cancer rates in gigantic mammals. Our study shows that it is feasible to estimate μ directly from pedigrees in natural populations, with wide-ranging implications for ecological and evolutionary research. ... Dataset baleen whale baleen whales toothed whales DataCite Metadata Store (German National Library of Science and Technology) |
institution |
Open Polar |
collection |
DataCite Metadata Store (German National Library of Science and Technology) |
op_collection_id |
ftdatacite |
language |
English |
topic |
pedigree baleen whales FOS Biological sciences mutation rate |
spellingShingle |
pedigree baleen whales FOS Biological sciences mutation rate Suárez-Menéndez, Marcos Bérubé, Martine Furni, Fabrício Rivera-Leon, Vania Heide-Jørgensen, Mads Peter Larsen, Finn Sears, Richard Ramp, Christian Eriksson, Britas Klemens Etienne, Rampal Robbins, Jooke Palsbøll, Per Wild pedigrees inform mutation rates and historic abundance in baleen whales ... |
topic_facet |
pedigree baleen whales FOS Biological sciences mutation rate |
description |
Phylogeny-based estimates suggesting a low germline mutation rate (μ) in baleen whales have influenced research ranging from assessments of whaling impacts to evolutionary cancer biology. We estimated μ directly from pedigrees in four baleen whale species for both the mitochondrial control region and nuclear genome. The results suggest values higher than those obtained through phylogeny-based estimates and similar to pedigree-based values for primates and toothed whales. Applying our estimate of μ reduces previous genetic–based estimates of pre-exploitation whale abundance by 86% and suggests that μ cannot explain low cancer rates in gigantic mammals. Our study shows that it is feasible to estimate μ directly from pedigrees in natural populations, with wide-ranging implications for ecological and evolutionary research. ... |
format |
Dataset |
author |
Suárez-Menéndez, Marcos Bérubé, Martine Furni, Fabrício Rivera-Leon, Vania Heide-Jørgensen, Mads Peter Larsen, Finn Sears, Richard Ramp, Christian Eriksson, Britas Klemens Etienne, Rampal Robbins, Jooke Palsbøll, Per |
author_facet |
Suárez-Menéndez, Marcos Bérubé, Martine Furni, Fabrício Rivera-Leon, Vania Heide-Jørgensen, Mads Peter Larsen, Finn Sears, Richard Ramp, Christian Eriksson, Britas Klemens Etienne, Rampal Robbins, Jooke Palsbøll, Per |
author_sort |
Suárez-Menéndez, Marcos |
title |
Wild pedigrees inform mutation rates and historic abundance in baleen whales ... |
title_short |
Wild pedigrees inform mutation rates and historic abundance in baleen whales ... |
title_full |
Wild pedigrees inform mutation rates and historic abundance in baleen whales ... |
title_fullStr |
Wild pedigrees inform mutation rates and historic abundance in baleen whales ... |
title_full_unstemmed |
Wild pedigrees inform mutation rates and historic abundance in baleen whales ... |
title_sort |
wild pedigrees inform mutation rates and historic abundance in baleen whales ... |
publisher |
Dryad |
publishDate |
2023 |
url |
https://dx.doi.org/10.5061/dryad.9kd51c5pq https://datadryad.org/stash/dataset/doi:10.5061/dryad.9kd51c5pq |
genre |
baleen whale baleen whales toothed whales |
genre_facet |
baleen whale baleen whales toothed whales |
op_relation |
https://dx.doi.org/10.1101/2022.10.06.510775 https://dx.doi.org/10.1126/science.adf2160 |
op_rights |
Creative Commons Zero v1.0 Universal https://creativecommons.org/publicdomain/zero/1.0/legalcode cc0-1.0 |
op_doi |
https://doi.org/10.5061/dryad.9kd51c5pq10.1101/2022.10.06.51077510.1126/science.adf2160 |
_version_ |
1789963775866044416 |