Data from: The neuroendocrine immunomodulatory axis-like pathway mediated by circulating haemocytes in pacific oyster Crassostrea gigas ...
The neuroendocrine-immune (NEI) regulatory network is a complex system, which plays an indispensable role in the immunity of host. In this study, a neuroendocrine immunomodulatory axis (NIA)-like pathway mediated by the nervous system and haemocytes was characterized in the oyster Crassostrea gigas....
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Online Access: | https://dx.doi.org/10.5061/dryad.7d6c5 https://datadryad.org/stash/dataset/doi:10.5061/dryad.7d6c5 |
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ftdatacite:10.5061/dryad.7d6c5 2024-02-04T09:59:43+01:00 Data from: The neuroendocrine immunomodulatory axis-like pathway mediated by circulating haemocytes in pacific oyster Crassostrea gigas ... Liu, Zhaoqun Zhou, Zhi Jiang, Qiufen Wang, Lingling Yi, Qilin Qiu, Limei Song, Linsheng 2017 https://dx.doi.org/10.5061/dryad.7d6c5 https://datadryad.org/stash/dataset/doi:10.5061/dryad.7d6c5 en eng Dryad https://dx.doi.org/10.1098/rsob.160289 Creative Commons Zero v1.0 Universal https://creativecommons.org/publicdomain/zero/1.0/legalcode cc0-1.0 Circulating haemocyte Membrane receptor Immune regulation Crassostrea gigas Neuroendocrine immunomodulatory axis Dataset dataset 2017 ftdatacite https://doi.org/10.5061/dryad.7d6c510.1098/rsob.160289 2024-01-05T01:14:15Z The neuroendocrine-immune (NEI) regulatory network is a complex system, which plays an indispensable role in the immunity of host. In this study, a neuroendocrine immunomodulatory axis (NIA)-like pathway mediated by the nervous system and haemocytes was characterized in the oyster Crassostrea gigas. Once invaded pathogen was recognized by the host, the nervous system would temporally release neurotransmitters to modulate the immune response. Instead of acting passively, oyster haemocytes were able to mediate neuronal immunomodulation promptly by controlling the expression of specific neurotransmitter receptors on cell surface and modulating their binding sensitivities, thus regulating intracellular concentration of Ca2+. This neural immunomodulation mediated by the nervous system and haemocytes could influence cellular immunity in oyster by affecting mRNA expression level of TNF genes, and humoral immunity by affecting the activities of key immune-related enzymes. In summary, though simple in structure, the ... : Figure and TableFigures & Tables ... Dataset Crassostrea gigas Pacific oyster DataCite Metadata Store (German National Library of Science and Technology) Pacific |
institution |
Open Polar |
collection |
DataCite Metadata Store (German National Library of Science and Technology) |
op_collection_id |
ftdatacite |
language |
English |
topic |
Circulating haemocyte Membrane receptor Immune regulation Crassostrea gigas Neuroendocrine immunomodulatory axis |
spellingShingle |
Circulating haemocyte Membrane receptor Immune regulation Crassostrea gigas Neuroendocrine immunomodulatory axis Liu, Zhaoqun Zhou, Zhi Jiang, Qiufen Wang, Lingling Yi, Qilin Qiu, Limei Song, Linsheng Data from: The neuroendocrine immunomodulatory axis-like pathway mediated by circulating haemocytes in pacific oyster Crassostrea gigas ... |
topic_facet |
Circulating haemocyte Membrane receptor Immune regulation Crassostrea gigas Neuroendocrine immunomodulatory axis |
description |
The neuroendocrine-immune (NEI) regulatory network is a complex system, which plays an indispensable role in the immunity of host. In this study, a neuroendocrine immunomodulatory axis (NIA)-like pathway mediated by the nervous system and haemocytes was characterized in the oyster Crassostrea gigas. Once invaded pathogen was recognized by the host, the nervous system would temporally release neurotransmitters to modulate the immune response. Instead of acting passively, oyster haemocytes were able to mediate neuronal immunomodulation promptly by controlling the expression of specific neurotransmitter receptors on cell surface and modulating their binding sensitivities, thus regulating intracellular concentration of Ca2+. This neural immunomodulation mediated by the nervous system and haemocytes could influence cellular immunity in oyster by affecting mRNA expression level of TNF genes, and humoral immunity by affecting the activities of key immune-related enzymes. In summary, though simple in structure, the ... : Figure and TableFigures & Tables ... |
format |
Dataset |
author |
Liu, Zhaoqun Zhou, Zhi Jiang, Qiufen Wang, Lingling Yi, Qilin Qiu, Limei Song, Linsheng |
author_facet |
Liu, Zhaoqun Zhou, Zhi Jiang, Qiufen Wang, Lingling Yi, Qilin Qiu, Limei Song, Linsheng |
author_sort |
Liu, Zhaoqun |
title |
Data from: The neuroendocrine immunomodulatory axis-like pathway mediated by circulating haemocytes in pacific oyster Crassostrea gigas ... |
title_short |
Data from: The neuroendocrine immunomodulatory axis-like pathway mediated by circulating haemocytes in pacific oyster Crassostrea gigas ... |
title_full |
Data from: The neuroendocrine immunomodulatory axis-like pathway mediated by circulating haemocytes in pacific oyster Crassostrea gigas ... |
title_fullStr |
Data from: The neuroendocrine immunomodulatory axis-like pathway mediated by circulating haemocytes in pacific oyster Crassostrea gigas ... |
title_full_unstemmed |
Data from: The neuroendocrine immunomodulatory axis-like pathway mediated by circulating haemocytes in pacific oyster Crassostrea gigas ... |
title_sort |
data from: the neuroendocrine immunomodulatory axis-like pathway mediated by circulating haemocytes in pacific oyster crassostrea gigas ... |
publisher |
Dryad |
publishDate |
2017 |
url |
https://dx.doi.org/10.5061/dryad.7d6c5 https://datadryad.org/stash/dataset/doi:10.5061/dryad.7d6c5 |
geographic |
Pacific |
geographic_facet |
Pacific |
genre |
Crassostrea gigas Pacific oyster |
genre_facet |
Crassostrea gigas Pacific oyster |
op_relation |
https://dx.doi.org/10.1098/rsob.160289 |
op_rights |
Creative Commons Zero v1.0 Universal https://creativecommons.org/publicdomain/zero/1.0/legalcode cc0-1.0 |
op_doi |
https://doi.org/10.5061/dryad.7d6c510.1098/rsob.160289 |
_version_ |
1789964688786718720 |