Data from: Mapping and validation of a major QTL affecting resistance to pancreas disease (salmonid alphavirus) in Atlantic salmon (Salmo salar) ...

• Main Authors: Gonen, Serap, Baranski, Matthew, Thorland, Ingunn, Norris, Ashie, Grove, Harald, Arnesen, Petter, Bakke, Håvard, Lien, Sigbjørn, Bishop, Stephen C., Houston, Ross D.
• Format: Dataset
• Language: English
• Published: Dryad 2015
• Subjects: Salmonid alphavirus; disease resistance; Salmo salar; Pancreas disease; QTL mapping; Sav’; Atlantic salmon
• Online Access: https://dx.doi.org/10.5061/dryad.5241h; https://datadryad.org/stash/dataset/doi:10.5061/dryad.5241h

Pancreas disease (PD), caused by a salmonid alphavirus (SAV), has a large negative economic and animal welfare impact on Atlantic salmon aquaculture. Evidence for genetic variation in host resistance to this disease has been reported, suggesting that selective breeding may potentially form an important component of disease control. The aim of this study was to explore the genetic architecture of resistance to PD, using survival data collected from two unrelated populations of Atlantic salmon; one challenged with SAV as fry in freshwater (POP 1) and one challenged with SAV as post-smolts in sea water (POP 2). Analyses of the binary survival data revealed a moderate-to-high heritability for host resistance to PD in both populations (fry POP 1 h2~0.5; post-smolt POP 2 h2~0.4). Subsets of both populations were genotyped for single nucleotide polymorphism markers, and six putative resistance quantitative trait loci (QTL) were identified. One of these QTL was mapped to the same location on chromosome 3 in both ... : Pancreas disease variance estimation and QTL mapping filesGenotype, phenotype and pedigree files for POP1 (fry) and POP2 (post-smolt)Pancreas_disease_data.zip ...