Data from: The loss of hemoglobin and myoglobin does not minimize oxidative stress in Antarctic icefishes ...
The unusual pattern of expression of hemoglobin (Hb) and myoglobin (Mb) among Antarctic notothenioid fishes provides an exceptional model system for assessing the impact of these proteins on oxidative stress. We tested the hypothesis that the lack of oxygen-binding proteins may reduce oxidative stre...
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Online Access: | https://dx.doi.org/10.5061/dryad.5228g https://datadryad.org/stash/dataset/doi:10.5061/dryad.5228g |
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ftdatacite:10.5061/dryad.5228g 2024-02-04T09:54:44+01:00 Data from: The loss of hemoglobin and myoglobin does not minimize oxidative stress in Antarctic icefishes ... O'Brien, Kristin M. Crockett, Elizabeth L. Philip, Jacques Oldham, Corey A. Hoffman, Megan Kuhn, Donald E. Barry, Ronald McLaughlin, Jessica 2017 https://dx.doi.org/10.5061/dryad.5228g https://datadryad.org/stash/dataset/doi:10.5061/dryad.5228g en eng Dryad https://dx.doi.org/10.1242/jeb.162503 Creative Commons Zero v1.0 Universal https://creativecommons.org/publicdomain/zero/1.0/legalcode cc0-1.0 Notothenia coriiceps Pseudochaenichthys georgianus Champsocephalus gunnari Chaenocephalus aceratus Antarctic fish Hemoglobin myoglobin Gobionotothen gibberifrons Chionodraco rastrospinosus Dataset dataset 2017 ftdatacite https://doi.org/10.5061/dryad.5228g10.1242/jeb.162503 2024-01-05T01:14:15Z The unusual pattern of expression of hemoglobin (Hb) and myoglobin (Mb) among Antarctic notothenioid fishes provides an exceptional model system for assessing the impact of these proteins on oxidative stress. We tested the hypothesis that the lack of oxygen-binding proteins may reduce oxidative stress. Levels and activity of pro-oxidants, small-molecule and enzymatic antioxidants, and levels of oxidized lipids and proteins in liver, oxidative skeletal muscle, and heart ventricle were quantified in five species of notothenioid fishes differing in the expression of Hb and Mb. Levels of ubiquitinated proteins and rates of protein degradation by the 20S proteasome were also quantified. Although levels of oxidized proteins and lipids, ubiquitinated proteins, and antioxidants are higher in red-blooded fishes than in Hb-less icefishes in some tissues, this pattern does not persist across all tissues. Expression of Mb is not associated with oxidative damage in heart ventricle, whereas the activity of citrate ... : Data Summary JEB O'Brien et al JEXBIO_2017_162503 ... Dataset Antarc* Antarctic DataCite Metadata Store (German National Library of Science and Technology) Antarctic |
institution |
Open Polar |
collection |
DataCite Metadata Store (German National Library of Science and Technology) |
op_collection_id |
ftdatacite |
language |
English |
topic |
Notothenia coriiceps Pseudochaenichthys georgianus Champsocephalus gunnari Chaenocephalus aceratus Antarctic fish Hemoglobin myoglobin Gobionotothen gibberifrons Chionodraco rastrospinosus |
spellingShingle |
Notothenia coriiceps Pseudochaenichthys georgianus Champsocephalus gunnari Chaenocephalus aceratus Antarctic fish Hemoglobin myoglobin Gobionotothen gibberifrons Chionodraco rastrospinosus O'Brien, Kristin M. Crockett, Elizabeth L. Philip, Jacques Oldham, Corey A. Hoffman, Megan Kuhn, Donald E. Barry, Ronald McLaughlin, Jessica Data from: The loss of hemoglobin and myoglobin does not minimize oxidative stress in Antarctic icefishes ... |
topic_facet |
Notothenia coriiceps Pseudochaenichthys georgianus Champsocephalus gunnari Chaenocephalus aceratus Antarctic fish Hemoglobin myoglobin Gobionotothen gibberifrons Chionodraco rastrospinosus |
description |
The unusual pattern of expression of hemoglobin (Hb) and myoglobin (Mb) among Antarctic notothenioid fishes provides an exceptional model system for assessing the impact of these proteins on oxidative stress. We tested the hypothesis that the lack of oxygen-binding proteins may reduce oxidative stress. Levels and activity of pro-oxidants, small-molecule and enzymatic antioxidants, and levels of oxidized lipids and proteins in liver, oxidative skeletal muscle, and heart ventricle were quantified in five species of notothenioid fishes differing in the expression of Hb and Mb. Levels of ubiquitinated proteins and rates of protein degradation by the 20S proteasome were also quantified. Although levels of oxidized proteins and lipids, ubiquitinated proteins, and antioxidants are higher in red-blooded fishes than in Hb-less icefishes in some tissues, this pattern does not persist across all tissues. Expression of Mb is not associated with oxidative damage in heart ventricle, whereas the activity of citrate ... : Data Summary JEB O'Brien et al JEXBIO_2017_162503 ... |
format |
Dataset |
author |
O'Brien, Kristin M. Crockett, Elizabeth L. Philip, Jacques Oldham, Corey A. Hoffman, Megan Kuhn, Donald E. Barry, Ronald McLaughlin, Jessica |
author_facet |
O'Brien, Kristin M. Crockett, Elizabeth L. Philip, Jacques Oldham, Corey A. Hoffman, Megan Kuhn, Donald E. Barry, Ronald McLaughlin, Jessica |
author_sort |
O'Brien, Kristin M. |
title |
Data from: The loss of hemoglobin and myoglobin does not minimize oxidative stress in Antarctic icefishes ... |
title_short |
Data from: The loss of hemoglobin and myoglobin does not minimize oxidative stress in Antarctic icefishes ... |
title_full |
Data from: The loss of hemoglobin and myoglobin does not minimize oxidative stress in Antarctic icefishes ... |
title_fullStr |
Data from: The loss of hemoglobin and myoglobin does not minimize oxidative stress in Antarctic icefishes ... |
title_full_unstemmed |
Data from: The loss of hemoglobin and myoglobin does not minimize oxidative stress in Antarctic icefishes ... |
title_sort |
data from: the loss of hemoglobin and myoglobin does not minimize oxidative stress in antarctic icefishes ... |
publisher |
Dryad |
publishDate |
2017 |
url |
https://dx.doi.org/10.5061/dryad.5228g https://datadryad.org/stash/dataset/doi:10.5061/dryad.5228g |
geographic |
Antarctic |
geographic_facet |
Antarctic |
genre |
Antarc* Antarctic |
genre_facet |
Antarc* Antarctic |
op_relation |
https://dx.doi.org/10.1242/jeb.162503 |
op_rights |
Creative Commons Zero v1.0 Universal https://creativecommons.org/publicdomain/zero/1.0/legalcode cc0-1.0 |
op_doi |
https://doi.org/10.5061/dryad.5228g10.1242/jeb.162503 |
_version_ |
1789974713197395968 |