Origins and evolutionary genomics of the novel 2013 avian-origin H7N9 influenza A virus in China: Early findings
In March and early April 2013, a new avian-origin influenza A (H7N9) virus (A-OIV) emerged in the eastern China. During the first week of April, the 18 infection cases have been confirmed and 6 people have died since March. This virus has caused global concern as a potential pandemic threat. Here we...
Main Authors: | , , |
---|---|
Format: | Report |
Language: | unknown |
Published: |
arXiv
2013
|
Subjects: | |
Online Access: | https://dx.doi.org/10.48550/arxiv.1304.1985 https://arxiv.org/abs/1304.1985 |
id |
ftdatacite:10.48550/arxiv.1304.1985 |
---|---|
record_format |
openpolar |
spelling |
ftdatacite:10.48550/arxiv.1304.1985 2023-05-15T15:34:22+02:00 Origins and evolutionary genomics of the novel 2013 avian-origin H7N9 influenza A virus in China: Early findings He, Jiankui Ning, Luwen Tong, Yin 2013 https://dx.doi.org/10.48550/arxiv.1304.1985 https://arxiv.org/abs/1304.1985 unknown arXiv arXiv.org perpetual, non-exclusive license http://arxiv.org/licenses/nonexclusive-distrib/1.0/ Populations and Evolution q-bio.PE Genomics q-bio.GN FOS Biological sciences Preprint Article article CreativeWork 2013 ftdatacite https://doi.org/10.48550/arxiv.1304.1985 2022-04-01T13:24:33Z In March and early April 2013, a new avian-origin influenza A (H7N9) virus (A-OIV) emerged in the eastern China. During the first week of April, the 18 infection cases have been confirmed and 6 people have died since March. This virus has caused global concern as a potential pandemic threat. Here we use evolutionary analysis to reconstruct the origins and early development of the A-OIV viruses. We found that A-OIV was derived from a reassortment of three avian flu virus strains, and substantial mutations have been detected. Our results highlight the need for systematic surveillance of influenza in birds, and provide evidence that the mixing of new genetic elements in avian can result in the emergence of viruses with pandemic potential in humans. : 8 pages, 5 figures, 2 table Report Avian flu DataCite Metadata Store (German National Library of Science and Technology) |
institution |
Open Polar |
collection |
DataCite Metadata Store (German National Library of Science and Technology) |
op_collection_id |
ftdatacite |
language |
unknown |
topic |
Populations and Evolution q-bio.PE Genomics q-bio.GN FOS Biological sciences |
spellingShingle |
Populations and Evolution q-bio.PE Genomics q-bio.GN FOS Biological sciences He, Jiankui Ning, Luwen Tong, Yin Origins and evolutionary genomics of the novel 2013 avian-origin H7N9 influenza A virus in China: Early findings |
topic_facet |
Populations and Evolution q-bio.PE Genomics q-bio.GN FOS Biological sciences |
description |
In March and early April 2013, a new avian-origin influenza A (H7N9) virus (A-OIV) emerged in the eastern China. During the first week of April, the 18 infection cases have been confirmed and 6 people have died since March. This virus has caused global concern as a potential pandemic threat. Here we use evolutionary analysis to reconstruct the origins and early development of the A-OIV viruses. We found that A-OIV was derived from a reassortment of three avian flu virus strains, and substantial mutations have been detected. Our results highlight the need for systematic surveillance of influenza in birds, and provide evidence that the mixing of new genetic elements in avian can result in the emergence of viruses with pandemic potential in humans. : 8 pages, 5 figures, 2 table |
format |
Report |
author |
He, Jiankui Ning, Luwen Tong, Yin |
author_facet |
He, Jiankui Ning, Luwen Tong, Yin |
author_sort |
He, Jiankui |
title |
Origins and evolutionary genomics of the novel 2013 avian-origin H7N9 influenza A virus in China: Early findings |
title_short |
Origins and evolutionary genomics of the novel 2013 avian-origin H7N9 influenza A virus in China: Early findings |
title_full |
Origins and evolutionary genomics of the novel 2013 avian-origin H7N9 influenza A virus in China: Early findings |
title_fullStr |
Origins and evolutionary genomics of the novel 2013 avian-origin H7N9 influenza A virus in China: Early findings |
title_full_unstemmed |
Origins and evolutionary genomics of the novel 2013 avian-origin H7N9 influenza A virus in China: Early findings |
title_sort |
origins and evolutionary genomics of the novel 2013 avian-origin h7n9 influenza a virus in china: early findings |
publisher |
arXiv |
publishDate |
2013 |
url |
https://dx.doi.org/10.48550/arxiv.1304.1985 https://arxiv.org/abs/1304.1985 |
genre |
Avian flu |
genre_facet |
Avian flu |
op_rights |
arXiv.org perpetual, non-exclusive license http://arxiv.org/licenses/nonexclusive-distrib/1.0/ |
op_doi |
https://doi.org/10.48550/arxiv.1304.1985 |
_version_ |
1766364795527757824 |