Studies of markers of vasculature and immunological systems in eyes of lumpfish, a North Atlantic Teleost ...

• Main Author: Hyde, Tatiana
• Format: Text
• Language: English
• Published: Memorial University of Newfoundland 2022
• Subjects: The Louse; Atlantic salmon; North Atlantic; Salmo salar
• Online Access: https://dx.doi.org/10.48336/np9w-v946; https://research.library.mun.ca/15888/

Lumpfish (Cyclopterus lumpus), a North Atlantic teleost, is used as a cleaner fish to delouse salmon in the commercial Atlantic Salmon (Salmo salar) farming industry. Lumpfish require high visual acuity to observe and consume prey, such as the louse on salmon skin. Hematopoiesis, a process in which stem and progenitor cells differentiate to form blood cellular components occurs primarily in the bone marrow, but during fetal development it can in rare cases occur in “extramedullary” structures such as the ocular choroid vasculature of the eye. The choroid vasculature is a specialized vasculature that services the posterior retina and accounts for the majority of the blood flow to the eye. The comparable vasculature structures between lumpfish and human provide a new opportunity for a new model system for studying vasculature biology. I propose that the development of the posterior vasculature and hematopoiesis system of the lumpfish eye involves unique expression markers that exaggerate and support natural ...