Metagenomic analysis of fecal and tissue samples from 18 endemic bat species in Switzerland revealed a diverse virus composition including potentially zoonotic viruses ...
Many recent disease outbreaks in humans had a zoonotic virus etiology. Bats in particular have been recognized as reservoirs to a large variety of viruses with the potential to cross-species transmission. In order to assess the risk of bats in Switzerland for such transmissions, we determined the vi...
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ftdatacite:10.3929/ethz-b-000528481 2024-04-28T08:41:11+00:00 Metagenomic analysis of fecal and tissue samples from 18 endemic bat species in Switzerland revealed a diverse virus composition including potentially zoonotic viruses ... Hardmeier, Isabelle Aeberhard, Nadja Qi, Weihong Schoenbaechler, Katja Kraettli, Hubert Hatt, Jean-Michel Fraefel, Cornel Kubacki, Jakub 2021 application/pdf https://dx.doi.org/10.3929/ethz-b-000528481 http://hdl.handle.net/20.500.11850/528481 en eng ETH Zurich info:eu-repo/semantics/openAccess Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 article-journal Text ScholarlyArticle Journal Article 2021 ftdatacite https://doi.org/10.3929/ethz-b-000528481 2024-04-02T12:34:54Z Many recent disease outbreaks in humans had a zoonotic virus etiology. Bats in particular have been recognized as reservoirs to a large variety of viruses with the potential to cross-species transmission. In order to assess the risk of bats in Switzerland for such transmissions, we determined the virome of tissue and fecal samples of 14 native and 4 migrating bat species. In total, sequences belonging to 39 different virus families, 16 of which are known to infect vertebrates, were detected. Contigs of coronaviruses, adenoviruses, hepeviruses, rotaviruses A and H, and parvoviruses with potential zoonotic risk were characterized in more detail. Most interestingly, in a ground stool sample of a Vespertilio murinus colony an almost complete genome of a Middle East respiratory syndrome-related coronavirus (MERS-CoV) was detected by Next generation sequencing and confirmed by PCR. In conclusion, bats in Switzerland naturally harbour many different viruses. Metagenomic analyses of non-invasive samples like ground ... : PLoS ONE, 16 (6) ... Article in Journal/Newspaper Vespertilio murinus DataCite Metadata Store (German National Library of Science and Technology) |
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DataCite Metadata Store (German National Library of Science and Technology) |
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language |
English |
description |
Many recent disease outbreaks in humans had a zoonotic virus etiology. Bats in particular have been recognized as reservoirs to a large variety of viruses with the potential to cross-species transmission. In order to assess the risk of bats in Switzerland for such transmissions, we determined the virome of tissue and fecal samples of 14 native and 4 migrating bat species. In total, sequences belonging to 39 different virus families, 16 of which are known to infect vertebrates, were detected. Contigs of coronaviruses, adenoviruses, hepeviruses, rotaviruses A and H, and parvoviruses with potential zoonotic risk were characterized in more detail. Most interestingly, in a ground stool sample of a Vespertilio murinus colony an almost complete genome of a Middle East respiratory syndrome-related coronavirus (MERS-CoV) was detected by Next generation sequencing and confirmed by PCR. In conclusion, bats in Switzerland naturally harbour many different viruses. Metagenomic analyses of non-invasive samples like ground ... : PLoS ONE, 16 (6) ... |
format |
Article in Journal/Newspaper |
author |
Hardmeier, Isabelle Aeberhard, Nadja Qi, Weihong Schoenbaechler, Katja Kraettli, Hubert Hatt, Jean-Michel Fraefel, Cornel Kubacki, Jakub |
spellingShingle |
Hardmeier, Isabelle Aeberhard, Nadja Qi, Weihong Schoenbaechler, Katja Kraettli, Hubert Hatt, Jean-Michel Fraefel, Cornel Kubacki, Jakub Metagenomic analysis of fecal and tissue samples from 18 endemic bat species in Switzerland revealed a diverse virus composition including potentially zoonotic viruses ... |
author_facet |
Hardmeier, Isabelle Aeberhard, Nadja Qi, Weihong Schoenbaechler, Katja Kraettli, Hubert Hatt, Jean-Michel Fraefel, Cornel Kubacki, Jakub |
author_sort |
Hardmeier, Isabelle |
title |
Metagenomic analysis of fecal and tissue samples from 18 endemic bat species in Switzerland revealed a diverse virus composition including potentially zoonotic viruses ... |
title_short |
Metagenomic analysis of fecal and tissue samples from 18 endemic bat species in Switzerland revealed a diverse virus composition including potentially zoonotic viruses ... |
title_full |
Metagenomic analysis of fecal and tissue samples from 18 endemic bat species in Switzerland revealed a diverse virus composition including potentially zoonotic viruses ... |
title_fullStr |
Metagenomic analysis of fecal and tissue samples from 18 endemic bat species in Switzerland revealed a diverse virus composition including potentially zoonotic viruses ... |
title_full_unstemmed |
Metagenomic analysis of fecal and tissue samples from 18 endemic bat species in Switzerland revealed a diverse virus composition including potentially zoonotic viruses ... |
title_sort |
metagenomic analysis of fecal and tissue samples from 18 endemic bat species in switzerland revealed a diverse virus composition including potentially zoonotic viruses ... |
publisher |
ETH Zurich |
publishDate |
2021 |
url |
https://dx.doi.org/10.3929/ethz-b-000528481 http://hdl.handle.net/20.500.11850/528481 |
genre |
Vespertilio murinus |
genre_facet |
Vespertilio murinus |
op_rights |
info:eu-repo/semantics/openAccess Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 |
op_doi |
https://doi.org/10.3929/ethz-b-000528481 |
_version_ |
1797571533069090816 |