Uterine responses to early pre-attachment embryos in the domestic dog and comparisons with other domestic animal species ...
In the dog, there is no luteolysis in the absence of pregnancy. Thus, this species lacks any anti-luteolytic endocrine signal as found in other species that modulate uterine function during the critical period of pregnancy establishment. Nevertheless, in the dog an embryo-maternal communication must...
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ftdatacite:10.3929/ethz-b-000220083 2024-04-28T08:15:23+00:00 Uterine responses to early pre-attachment embryos in the domestic dog and comparisons with other domestic animal species ... Graubner, Felix R. Gram, Aykut Kautz, Ewa Bauersachs, Stefan Aslan, Selim Agaoglu, Ali R. Boos, Alois Kowalewski, Mariusz P. 2017 application/pdf https://dx.doi.org/10.3929/ethz-b-000220083 http://hdl.handle.net/20.500.11850/220083 en eng ETH Zurich info:eu-repo/semantics/openAccess Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 dog Canis lupus familiaris embryo-maternal communication early pregnancy article-journal Text ScholarlyArticle Journal Article 2017 ftdatacite https://doi.org/10.3929/ethz-b-000220083 2024-04-02T12:33:25Z In the dog, there is no luteolysis in the absence of pregnancy. Thus, this species lacks any anti-luteolytic endocrine signal as found in other species that modulate uterine function during the critical period of pregnancy establishment. Nevertheless, in the dog an embryo-maternal communication must occur in order to prevent rejection of embryos. Based on this hypothesis, we performed microarray analysis of canine uterine samples collected during pre-attachment phase (days 10-12) and in corresponding non-pregnant controls, in order to elucidate the embryo attachment signal. An additional goal was to identify differences in uterine responses to pre-attachment embryos between dogs and other mammalian species exhibiting different reproductive patterns with regard to luteolysis, implantation, and preparation for placentation. Therefore, the canine microarray data were compared with gene sets from pigs, cattle, horses, and humans. We found 412 genes differentially regulated between the two experimental groups. ... : Biology of Reproduction, 97 (2) ... Article in Journal/Newspaper Canis lupus DataCite Metadata Store (German National Library of Science and Technology) |
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collection |
DataCite Metadata Store (German National Library of Science and Technology) |
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language |
English |
topic |
dog Canis lupus familiaris embryo-maternal communication early pregnancy |
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dog Canis lupus familiaris embryo-maternal communication early pregnancy Graubner, Felix R. Gram, Aykut Kautz, Ewa Bauersachs, Stefan Aslan, Selim Agaoglu, Ali R. Boos, Alois Kowalewski, Mariusz P. Uterine responses to early pre-attachment embryos in the domestic dog and comparisons with other domestic animal species ... |
topic_facet |
dog Canis lupus familiaris embryo-maternal communication early pregnancy |
description |
In the dog, there is no luteolysis in the absence of pregnancy. Thus, this species lacks any anti-luteolytic endocrine signal as found in other species that modulate uterine function during the critical period of pregnancy establishment. Nevertheless, in the dog an embryo-maternal communication must occur in order to prevent rejection of embryos. Based on this hypothesis, we performed microarray analysis of canine uterine samples collected during pre-attachment phase (days 10-12) and in corresponding non-pregnant controls, in order to elucidate the embryo attachment signal. An additional goal was to identify differences in uterine responses to pre-attachment embryos between dogs and other mammalian species exhibiting different reproductive patterns with regard to luteolysis, implantation, and preparation for placentation. Therefore, the canine microarray data were compared with gene sets from pigs, cattle, horses, and humans. We found 412 genes differentially regulated between the two experimental groups. ... : Biology of Reproduction, 97 (2) ... |
format |
Article in Journal/Newspaper |
author |
Graubner, Felix R. Gram, Aykut Kautz, Ewa Bauersachs, Stefan Aslan, Selim Agaoglu, Ali R. Boos, Alois Kowalewski, Mariusz P. |
author_facet |
Graubner, Felix R. Gram, Aykut Kautz, Ewa Bauersachs, Stefan Aslan, Selim Agaoglu, Ali R. Boos, Alois Kowalewski, Mariusz P. |
author_sort |
Graubner, Felix R. |
title |
Uterine responses to early pre-attachment embryos in the domestic dog and comparisons with other domestic animal species ... |
title_short |
Uterine responses to early pre-attachment embryos in the domestic dog and comparisons with other domestic animal species ... |
title_full |
Uterine responses to early pre-attachment embryos in the domestic dog and comparisons with other domestic animal species ... |
title_fullStr |
Uterine responses to early pre-attachment embryos in the domestic dog and comparisons with other domestic animal species ... |
title_full_unstemmed |
Uterine responses to early pre-attachment embryos in the domestic dog and comparisons with other domestic animal species ... |
title_sort |
uterine responses to early pre-attachment embryos in the domestic dog and comparisons with other domestic animal species ... |
publisher |
ETH Zurich |
publishDate |
2017 |
url |
https://dx.doi.org/10.3929/ethz-b-000220083 http://hdl.handle.net/20.500.11850/220083 |
genre |
Canis lupus |
genre_facet |
Canis lupus |
op_rights |
info:eu-repo/semantics/openAccess Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 |
op_doi |
https://doi.org/10.3929/ethz-b-000220083 |
_version_ |
1797580983671717888 |